KEGG   PATHWAY: ptr00330
Entry
ptr00330                    Pathway                                
Name
Arginine and proline metabolism - Pan troglodytes (chimpanzee)
Class
Metabolism; Amino acid metabolism
Pathway map
ptr00330  Arginine and proline metabolism
ptr00330

Module
ptr_M00015  Proline biosynthesis, glutamate => proline [PATH:ptr00330]
ptr_M00047  Creatine pathway [PATH:ptr00330]
ptr_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:ptr00330]
ptr_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:ptr00330]
ptr_M00970  Proline degradation, proline => glutamate [PATH:ptr00330]
ptr_M00972  Proline metabolism [PATH:ptr00330]
Other DBs
GO: 0006525 0006560
Organism
Pan troglodytes (chimpanzee) [GN:ptr]
Gene
453401  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
749982  GAMT; guanidinoacetate N-methyltransferase isoform X1 [KO:K00542] [EC:2.1.1.2]
461770  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
453185  CKB; creatine kinase B-type isoform X1 [KO:K00933] [EC:2.7.3.2]
100608872  creatine kinase U-type, mitochondrial isoform X1 [KO:K00933] [EC:2.7.3.2]
453384  creatine kinase U-type, mitochondrial isoform X1 [KO:K00933] [EC:2.7.3.2]
744935  CKM; creatine kinase M-type [KO:K27382] [EC:2.7.3.2]
469170  AZIN2; antizyme inhibitor 2 isoform X1 [KO:K01583] [EC:4.1.1.19]
459027  ODC1; ornithine decarboxylase isoform X1 [KO:K01581] [EC:4.1.1.17]
107974880  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
739762  spermine synthase [KO:K00802] [EC:2.5.1.22]
472092  AMD1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
107975990  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
458074  SMOX; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
464931  ALDH1B1; aldehyde dehydrogenase X, mitochondrial isoform X1 [KO:K00128] [EC:1.2.1.3]
107967644  ALDH2; aldehyde dehydrogenase, mitochondrial isoform X1 [KO:K00128] [EC:1.2.1.3]
462033  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
457478  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
455474  CNDP1; beta-Ala-His dipeptidase isoform X5 [KO:K05604] [EC:3.4.13.20]
455473  CNDP2; cytosolic non-specific dipeptidase isoform X1 [KO:K08660] [EC:3.4.13.18]
451368  CARNS1; carnosine synthase 1 isoform X2 [KO:K14755] [EC:6.3.2.11]
455216  SAT2; thialysine N-epsilon-acetyltransferase isoform X2 [KO:K00657] [EC:2.3.1.57]
107971113  SAT1; diamine acetyltransferase 1 isoform X1 [KO:K00657] [EC:2.3.1.57]
465588  MAOB; amine oxidase [flavin-containing] B isoform X1 [KO:K00274] [EC:1.4.3.4]
743285  MAOA; amine oxidase [flavin-containing] A [KO:K00274] [EC:1.4.3.4]
469130  AGMAT; guanidino acid hydrolase, mitochondrial [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
467139  NOS1; nitric oxide synthase 1 isoform X2 [KO:K13240] [EC:1.14.13.39]
455026  NOS2; nitric oxide synthase, inducible isoform X1 [KO:K13241] [EC:1.14.13.39]
463893  NOS3; nitric oxide synthase 3 isoform X2 [KO:K13242] [EC:1.14.13.39]
452985  ARG2; arginase-2, mitochondrial isoform X2 [KO:K01476] [EC:3.5.3.1]
462999  ARG1; arginase-1 [KO:K01476] [EC:3.5.3.1]
450803  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
472886  PYCR3; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
454977  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [KO:K00286] [EC:1.5.1.2]
457779  PYCR2; pyrroline-5-carboxylate reductase 2 isoform X2 [KO:K00286] [EC:1.5.1.2]
107970355  PRODH; proline dehydrogenase 1, mitochondrial isoform X1 [KO:K00318] [EC:1.5.5.2]
456575  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
450629  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
461132  LAP3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
748564  P4HA3; prolyl 4-hydroxylase subunit alpha-3 isoform X2 [KO:K00472] [EC:1.14.11.2]
450891  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
462047  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
469076  PRODH2; hydroxyproline dehydrogenase isoform X1 [KO:K11394] [EC:1.5.5.3]
450664  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
747942  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 isoform X1 [KO:K14454] [EC:2.6.1.1]
467989  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
742884  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
743881  DAO; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
112204140  L3HYPDH; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
ptr00020  Citrate cycle (TCA cycle)
ptr00220  Arginine biosynthesis
ptr00250  Alanine, aspartate and glutamate metabolism
ptr00260  Glycine, serine and threonine metabolism
ptr00270  Cysteine and methionine metabolism
ptr00310  Lysine degradation
ptr00410  beta-Alanine metabolism
ptr00470  D-Amino acid metabolism
ptr00480  Glutathione metabolism
ptr00630  Glyoxylate and dicarboxylate metabolism
ptr00650  Butanoate metabolism
ptr00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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