KEGG   PATHWAY: pviv00564
Entry
pviv00564                   Pathway                                
Name
Glycerophospholipid metabolism - Prionailurus viverrinus (fishing cat)
Class
Metabolism; Lipid metabolism
Pathway map
pviv00564  Glycerophospholipid metabolism
pviv00564

Module
pviv_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:pviv00564]
pviv_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:pviv00564]
pviv_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:pviv00564]
Other DBs
GO: 0006650
Organism
Prionailurus viverrinus (fishing cat) [GN:pviv]
Gene
125174908  GPD1L; glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
125169949  GPD1; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic isoform X1 [KO:K00006] [EC:1.1.1.8]
125172538  GPD2; glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
125162575  GPAT2; glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
125148134  GPAM; glycerol-3-phosphate acyltransferase 1, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
125164015  GPAT4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
125164346  GPAT3; glycerol-3-phosphate acyltransferase 3 isoform X1 [KO:K13506] [EC:2.3.1.15]
125150217  AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X1 [KO:K13509] [EC:2.3.1.51]
125165849  AGPAT1; 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha [KO:K13509] [EC:2.3.1.51]
125159076  AGPAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
125165222  AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
125163640  AGPAT5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon isoform X1 [KO:K19007] [EC:2.3.1.51]
125162199  LCLAT1; lysocardiolipin acyltransferase 1 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
125165394  MBOAT1; lysophospholipid acyltransferase 1 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
125158320  MBOAT2; lysophospholipid acyltransferase 2 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
125147763  GNPAT; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
125151528  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X1 [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
125159747  PLPP2; phospholipid phosphatase 2 isoform X1 [KO:K01080] [EC:3.1.3.4]
125163374  PLPP1; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
125172547  PLPP3; phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
125162221  LPIN1; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
125162586  LPIN3; phosphatidate phosphatase LPIN3 isoform X1 [KO:K15728] [EC:3.1.3.4]
125149063  LPIN2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
125148018  PLPP4; phospholipid phosphatase 4 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
125163886  PLPP5; phospholipid phosphatase 5 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
125151436  DGKE; diacylglycerol kinase epsilon isoform X1 [KO:K00901] [EC:2.7.1.107]
125159157  DGKQ; diacylglycerol kinase theta isoform X1 [KO:K00901] [EC:2.7.1.107]
125166379  DGKH; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
125160099  DGKB; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
125160819  DGKI; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
125175682  DGKG; diacylglycerol kinase gamma [KO:K00901] [EC:2.7.1.107]
125176299  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
125170845  DGKA; diacylglycerol kinase alpha isoform X1 [KO:K00901] [EC:2.7.1.107]
125157283  DGKK; diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
125172836  DGKD; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
125171034  CHPT1; cholinephosphotransferase 1 isoform X1 [KO:K00994] [EC:2.7.8.2]
125173009  CEPT1; choline/ethanolaminephosphotransferase 1 isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
125151242  PLD2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
125174683  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
125152912  PLD3; 5'-3' exonuclease PLD3 [KO:K16860] [EC:3.1.4.4]
125168555  PLD4; 5'-3' exonuclease PLD4 isoform X1 [KO:K16860] [EC:3.1.4.4]
125153395  LCAT; phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
125173848  PLA2G2F; group IIF secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
125154454  group 10 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
125148430  PLA2G12B; group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
125148862  PLA2G3; group 3 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
125163576  PLA2G12A; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
125149347  PLA2G1B; phospholipase A2 [KO:K01047] [EC:3.1.1.4]
125171810  PLA2G2C; putative inactive group IIC secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
125172728  group IID secretory phospholipase A2-like isoform X1 [KO:K01047] [EC:3.1.1.4]
125172812  group IIE secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
125173197  phospholipase A2 group V isoform X1 [KO:K01047] [EC:3.1.1.4]
125167867  PLA2G4E; cytosolic phospholipase A2 epsilon [KO:K16342] [EC:3.1.1.4]
125168236  PLA2G4F; cytosolic phospholipase A2 zeta [KO:K16342] [EC:3.1.1.4]
125168350  PLA2G4D; cytosolic phospholipase A2 delta [KO:K16342] [EC:3.1.1.4]
125155750  PLA2G4A; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
125169896  PLA2G6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
125162342  PLB1; phospholipase B1, membrane-associated isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
125176962  phospholipase A and acyltransferase 3 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
125153279  LPCAT2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
125162205  LPCAT1; lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
125169009  LPCAT4; lysophospholipid acyltransferase LPCAT4 isoform X1 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
125170246  LPCAT3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
125156593  LYPLA1; acyl-protein thioesterase 1 [KO:K06128] [EC:3.1.1.5]
125152710  PLA2G15; phospholipase A2 group XV isoform X1 [KO:K06129] [EC:3.1.1.5]
125173656  LYPLA2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
125156605  PNPLA6; patatin-like phospholipase domain-containing protein 6 isoform X1 [KO:K14676] [EC:3.1.1.5]
125150549  PNPLA7; patatin-like phospholipase domain-containing protein 7 isoform X1 [KO:K14676] [EC:3.1.1.5]
125161832  GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
125148128  CHAT; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
125154577  ACHE; acetylcholinesterase isoform X1 [KO:K01049] [EC:3.1.1.7]
125176260  CHKA; choline kinase alpha isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
125170237  CHKB; choline/ethanolamine kinase [KO:K14156] [EC:2.7.1.32 2.7.1.82]
125158486  PHOSPHO1; phosphoethanolamine/phosphocholine phosphatase isoform X1 [KO:K06124] [EC:3.1.3.75]
125174947  PCYT1A; choline-phosphate cytidylyltransferase A isoform X1 [KO:K00968] [EC:2.7.7.15]
125157211  PCYT1B; choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
125163086  SELENOI; ethanolaminephosphotransferase 1 isoform X1 [KO:K00993] [EC:2.7.8.1]
125169964  ETNK1; ethanolamine kinase 1 isoform X1 [KO:K00894] [EC:2.7.1.82]
125155142  ETNK2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
125151631  PCYT2; ethanolamine-phosphate cytidylyltransferase isoform X1 [KO:K00967] [EC:2.7.7.14]
125163977  ETNPPL; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
125151447  PEMT; phosphatidylethanolamine N-methyltransferase isoform X1 [KO:K00551] [EC:2.1.1.17 2.1.1.71]
125162536  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
125164231  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
125175425  phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
125156144  PTDSS1; phosphatidylserine synthase 1 isoform X1 [KO:K08729] [EC:2.7.8.-]
125146780  PTDSS2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
125148738  PISD; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
125152013  PGS1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial isoform X1 [KO:K00995] [EC:2.7.8.5]
125162368  CRLS1; cardiolipin synthase (CMP-forming) isoform X1 [KO:K08744] [EC:2.7.8.41]
125159358  TAFAZZIN; tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
125155118  LPGAT1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform X1 [KO:K13514] [EC:2.3.1.-]
125154739  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X1 [KO:K00999] [EC:2.7.8.11]
125153381  MBOAT7; lysophospholipid acyltransferase 7 isoform X1 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
pviv00010  Glycolysis / Gluconeogenesis
pviv00260  Glycine, serine and threonine metabolism
pviv00561  Glycerolipid metabolism
pviv00562  Inositol phosphate metabolism
pviv00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
pviv00565  Ether lipid metabolism
pviv00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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