 | | PATHWAY: rn00400 | |
Entry |
|
Name |
Phenylalanine, tyrosine and tryptophan biosynthesis |
Class |
Metabolism; Amino acid metabolism
|
Pathway map |
rn00400 | Phenylalanine, tyrosine and tryptophan biosynthesis |

|
Module |
M00022 | Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:rn00400] |
M00023 | Tryptophan biosynthesis, chorismate => tryptophan [PATH:rn00400] |
M00024 | Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:rn00400] |
M00025 | Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:rn00400] |
M00040 | Tyrosine biosynthesis, chorismate => arogenate => tyrosine [PATH:rn00400] |
M00910 | Phenylalanine biosynthesis, chorismate => arogenate => phenylalanine [PATH:rn00400] |
|
Other DBs |
|
Reaction |
R00674 | L-serine hydro-lyase (adding indole; L-tryptophan-forming) |
R00688 | L-phenylalanine:NAD+ oxidoreductase (deaminating) |
R00689 | L-phenylalanine:oxygen oxidoreductase (deaminating) |
R00691 | L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming) |
R00692 | L-phenylalanine:pyruvate aminotransferase |
R00694 | L-phenylalanine:2-oxoglutarate aminotransferase |
R00729 | L-tyrosine:oxygen oxidoreductase (deaminating) |
R00732 | L-arogenate:NAD+ oxidoreductase |
R00733 | L-arogenate:NADP+ oxidoreductase |
R00734 | L-tyrosine:2-oxoglutarate aminotransferase |
R00985 | chorismate pyruvate-lyase (amino-accepting; anthranilate-forming) |
R00986 | chorismate pyruvate-lyase (amino-accepting) |
R01073 | N-(5-phospho-D-ribosyl)anthranilate:pyrophosphate phosphoribosyl-transferase |
R01373 | prephenate hydro-lyase (decarboxylating; phenylpyruvate-forming) |
R01627 | 3-dehydroshikimate hydro-lyase |
R01714 | 5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate-forming) |
R01715 | chorismate pyruvatemutase |
R01728 | prephenate:NAD+ oxidoreductase(decarboxylating) |
R01730 | prephenate:NADP+ oxidoreductase(decarboxylating) |
R01731 | L-arogenate:2-oxoglutarate aminotransferase |
R01795 | L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating) |
R01826 | phosphoenolpyruvate:D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate hydrolysing, 2-carboxy-2-oxoethyl-forming) |
R01872 | L-quinate:NAD+ 3-oxidoreductase; quinate:NAD+ 5-oxidoreductase |
R01873 | quinate:pyrroloquinoline-quinone 3-oxidoreductase; quinate:pyrroloquinoline-quinone 5-oxidoreductase |
R02340 | (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase |
R02412 | ATP:shikimate 3-phosphotransferase |
R02413 | shikimate:NADP+ 3-oxidoreductase |
R02415 | shikimate:pyrroloquinoline-quinone 3-oxidoreductase |
R02722 | L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming] |
R03083 | 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate phosphate-lyase (cyclyzing) |
R03084 | 3-dehydroquinate hydro-lyase |
R03460 | phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase |
R03508 | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase(cyclizing) |
R03509 | N-(5-phospho-beta-D-ribosyl)anthranilate ketol-isomerase |
R06846 | L-quinate:NADP+ 3-oxidoreductase |
R06847 | shikimate:NAD+ 3-oxidoreductase |
R07276 | L-arogenate:2-oxoglutarate aminotransferase |
R08568 | L-aspartate 4-semialdehyde:1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate methylglyoxaltransferase |
R08569 | 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate:NAD+ oxidoreductase (deaminating) |
R09254 | L-tyrosine:pyruvate aminotransferase |
R09830 | L-tyrosine:NAD+ oxidoreductase (deaminating) |
R10049 | 2-oxopropanal:D-fructose 1,6-bisphosphate glycerone-phosphotransferase |
R10050 | 2-oxopropanal:D-fructose 1-phosphate glycerone-phosphotransferase |
R10500 | acetyl-CoA:phenylpyruvate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming) |
R10501 | 2-benzylmalate hydro-lyase (3-benzylmalate-forming) |
R10502 | 3-benzylmalate:NAD+ oxidoreductase (decarboxylating) |
R10503 | L-amino acid:2-oxo-4-phenylbutyric-acid aminotransferase |
R10583 | chorismate pyruvate-hydrolase |
R10597 | chorismate pyruvate-lyase (3-hydroxybenzoate-forming) |
|
Compound |
C00119 | 5-Phospho-alpha-D-ribose 1-diphosphate |
C00279 | D-Erythrose 4-phosphate |
C00354 | D-Fructose 1,6-bisphosphate |
C00441 | L-Aspartate 4-semialdehyde |
C01179 | 3-(4-Hydroxyphenyl)pyruvate |
C01269 | 5-O-(1-Carboxyvinyl)-3-phosphoshikimate |
C01302 | 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate |
C03506 | Indoleglycerol phosphate |
C04302 | N-(5-Phospho-D-ribosyl)anthranilate |
C04691 | 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate |
C16848 | 6-Deoxy-5-ketofructose 1-phosphate |
C16850 | 2-Amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid |
C20327 | 2-Oxo-4-phenylbutyric acid |
C20710 | (4R,5R)-4,5-Dihydroxycyclohexa-1(6),2-diene-1-carboxylate |
|
Related pathway |
rn00010 | Glycolysis / Gluconeogenesis |
rn00130 | Ubiquinone and other terpenoid-quinone biosynthesis |
rn00403 | Indole diterpene alkaloid biosynthesis |
rn00710 | Carbon fixation by Calvin cycle |
rn00901 | Indole alkaloid biosynthesis |
rn00940 | Phenylpropanoid biosynthesis |
rn00950 | Isoquinoline alkaloid biosynthesis |
rn00960 | Tropane, piperidine and pyridine alkaloid biosynthesis |
rn01053 | Biosynthesis of siderophore group nonribosomal peptides |
rn01059 | Biosynthesis of enediyne antibiotics |
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KO pathway |
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