KEGG   PATHWAY: roa00630
Entry
roa00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Rhodococcus opacus PD630
Class
Metabolism; Carbohydrate metabolism
Pathway map
roa00630  Glyoxylate and dicarboxylate metabolism
roa00630

Module
roa_M00012  Glyoxylate cycle [PATH:roa00630]
roa_M00621  Glycine cleavage system [PATH:roa00630]
roa_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:roa00630]
Other DBs
GO: 0046487 0043648
Organism
Rhodococcus opacus PD630 [GN:roa]
Gene
Pd630_LPD06301  Isocitrate lyase [KO:K01637] [EC:4.1.3.1]
Pd630_LPD03255  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Pd630_LPD00778  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Pd630_LPD05758  putative acyl--CoA ligase YtcI [KO:K01895] [EC:6.2.1.1]
Pd630_LPD07439  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Pd630_LPD06940  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Pd630_LPD04984  Malate synthase G [KO:K01638] [EC:2.3.3.9]
Pd630_LPD06792  Malate synthase G [KO:K01638] [EC:2.3.3.9]
Pd630_LPD02895  Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Pd630_LPD01510  Putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
Pd630_LPD01514  Citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
Pd630_LPD05750  Citrate synthase [KO:K01647] [EC:2.3.3.1]
Pd630_LPD04444  Putative citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
Pd630_LPD03957  Aconitate hydratase [KO:K01681] [EC:4.2.1.3]
Pd630_LPD06597  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
Pd630_LPD16138  Uncharacterized protein [KO:K00626] [EC:2.3.1.9]
Pd630_LPD05582  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD02292  Uncharacterized protein [KO:K00626] [EC:2.3.1.9]
Pd630_LPD00605  Putative acyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD02440  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD01777  Putative acetyl-CoA C-acetyltransferase vraB [KO:K00626] [EC:2.3.1.9]
Pd630_LPD04346  Uncharacterized protein [KO:K00626] [EC:2.3.1.9]
Pd630_LPD06041  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD13043  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD07367  3-ketoacyl-CoA thiolase B, peroxisomal [KO:K00626] [EC:2.3.1.9]
Pd630_LPD07266  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD07268  putative acetyl-CoA acyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD06744  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD01724  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD01189  Non-specific lipid-transfer protein [KO:K00626] [EC:2.3.1.9]
Pd630_LPD05455  putative acetyl-CoA acyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD02467  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD00692  Uncharacterized protein [KO:K00626] [EC:2.3.1.9]
Pd630_LPD04796  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD05762  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD07706  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD01184  Putative acyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD01076  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD01906  Uncharacterized protein [KO:K00626] [EC:2.3.1.9]
Pd630_LPD02755  Putative acyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD03584  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD00243  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD04501  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD07839  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
Pd630_LPD06943  hypothetical protein [KO:K17865] [EC:4.2.1.55]
Pd630_LPD05583  Uncharacterized protein yqjC [KO:K05606] [EC:5.1.99.1]
Pd630_LPD00081  Acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Pd630_LPD17024  Acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Pd630_LPD07106  Acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Pd630_LPD02942  Acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Pd630_LPD02955  putative propionyl-CoA carboxylase beta chain 5 [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
Pd630_LPD00083  putative propionyl-CoA carboxylase beta chain 5 [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
Pd630_LPD02954  hypothetical protein [KO:K27095]
Pd630_LPD05303  Propionyl-CoA carboxylase beta chain [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
Pd630_LPD03979  putative methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
Pd630_LPD03980  putative methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
Pd630_LPD04350  Glycolate oxidase subunit glcD [KO:K00104] [EC:1.1.99.14]
Pd630_LPD05729  Glycolate oxidase subunit glcD [KO:K00104] [EC:1.1.99.14]
Pd630_LPD07702  Glycolate oxidase subunit glcD [KO:K00104] [EC:1.1.99.14]
Pd630_LPD04559  Glycolate oxidase subunit glcD [KO:K00104] [EC:1.1.99.14]
Pd630_LPD00753  Catalase [KO:K03781] [EC:1.11.1.6]
Pd630_LPD07752  Catalase HPII [KO:K03781] [EC:1.11.1.6]
Pd630_LPD02570  Catalase [KO:K03781] [EC:1.11.1.6]
Pd630_LPD02461  Catalase [KO:K03781] [EC:1.11.1.6]
Pd630_LPD04819  Protein SrpA [KO:K03781] [EC:1.11.1.6]
Pd630_LPD04548  Catalase [KO:K03781] [EC:1.11.1.6]
Pd630_LPD01435  Glyoxylate reductase [KO:K00015] [EC:1.1.1.26]
Pd630_LPD01862  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Pd630_LPD05283  Uncharacterized protein [KO:K01091] [EC:3.1.3.18]
Pd630_LPD05884  Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Pd630_LPD04277  Type-1 glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
Pd630_LPD05254  Glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
Pd630_LPD05264  putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
Pd630_LPD06980  Glutamine synthetase 3 [KO:K01915] [EC:6.3.1.2]
Pd630_LPD05981  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Pd630_LPD02486  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Pd630_LPD07166  Serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
Pd630_LPD04987  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
Pd630_LPD07163  Glycine dehydrogenase [decarboxylating] [KO:K00281] [EC:1.4.4.2]
Pd630_LPD05245  Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
Pd630_LPD07164  Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
Pd630_LPD01804  Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
Pd630_LPD07578  Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
Pd630_LPD16176  Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
Pd630_LPD07696  Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
Pd630_LPD06320  Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
Pd630_LPD07161  Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
Pd630_LPD04992  Glycine cleavage system H protein [KO:K02437]
Pd630_LPD07165  Glycine cleavage system H protein [KO:K02437]
Pd630_LPD05988  putative glycine cleavage system H protein [KO:K02437]
Pd630_LPD06801  Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
Pd630_LPD01789  Putative hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
Pd630_LPD06803  Uncharacterized protein [KO:K01816] [EC:5.3.1.22]
Pd630_LPD06802  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
Pd630_LPD06800  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
Pd630_LPD05238  Uncharacterized protein [KO:K00865] [EC:2.7.1.165]
Pd630_LPD01313  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
Pd630_LPD01434  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
Pd630_LPD06613  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
Pd630_LPD07678  Glycerate kinase 2 [KO:K00865] [EC:2.7.1.165]
Pd630_LPD01919  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
Pd630_LPD03633  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
Pd630_LPD07833  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
Pd630_LPD01315  putative tartrate dehydrogenase/decarboxylase ttuC' [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Pd630_LPD06882  KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Pd630_LPD06562  KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Pd630_LPD06691  Putative KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Pd630_LPD02650  2-oxoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Pd630_LPD05979  Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Pd630_LPD06275  Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Pd630_LPD06304  Acetamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
roa00010  Glycolysis / Gluconeogenesis
roa00020  Citrate cycle (TCA cycle)
roa00030  Pentose phosphate pathway
roa00053  Ascorbate and aldarate metabolism
roa00071  Fatty acid degradation
roa00230  Purine metabolism
roa00250  Alanine, aspartate and glutamate metabolism
roa00260  Glycine, serine and threonine metabolism
roa00620  Pyruvate metabolism
roa00710  Carbon fixation by Calvin cycle
roa00750  Vitamin B6 metabolism
roa00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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