KEGG   PATHWAY: sem00230
Entry
sem00230                    Pathway                                
Name
Purine metabolism - Salmonella enterica subsp. enterica serovar Typhimurium T000240
Class
Metabolism; Nucleotide metabolism
Pathway map
sem00230  Purine metabolism
sem00230

Module
sem_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sem00230]
sem_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sem00230]
sem_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sem00230]
sem_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sem00230]
sem_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sem00230]
Other DBs
GO: 0006163 0042278
Organism
Salmonella enterica subsp. enterica serovar Typhimurium T000240 [GN:sem]
Gene
STMDT12_C32410  nudF; ADP-ribose pyrophosphatase NudF [KO:K01515] [EC:3.6.1.13 3.6.1.-]
STMDT12_C35490  nudE; ADP-ribose diphosphatase NudE [KO:K08312] [EC:3.6.1.-]
STMDT12_C46940  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
STMDT12_C07540  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
STMDT12_C18010  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
STMDT12_C23840  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
STMDT12_C43120  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
STMDT12_C25190  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
STMDT12_C19070  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
STMDT12_C25850  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
STMDT12_C25180  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
STMDT12_C05970  phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
STMDT12_C05980  phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
STMDT12_C25060  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
STMDT12_C12510  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
STMDT12_C43130  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
STMDT12_C05460  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
STMDT12_C05580  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
STMDT12_C29760  surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
STMDT12_C07370  UMP phosphatase [KO:K02566] [EC:3.1.3.5]
STMDT12_C35510  putative hydrolase [KO:K20881] [EC:3.1.3.-]
STMDT12_C05540  inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
STMDT12_C24400  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
STMDT12_C46950  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
STMDT12_C04530  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
STMDT12_C26820  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
STMDT12_C01710  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
STMDT12_C25280  inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
STMDT12_C25440  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
STMDT12_C47090  NTPase [KO:K01529] [EC:3.6.1.73]
STMDT12_C31560  putative deoxyribonucleotide triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
STMDT12_C03180  xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
STMDT12_C24560  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
STMDT12_C25270  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
STMDT12_C01420  guanosine 5'-monophosphate oxidoreductase [KO:K00364] [EC:1.7.1.7]
STMDT12_C37970  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
STMDT12_C22980  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
STMDT12_C28610  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
STMDT12_C22990  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
STMDT12_C28620  nrdF; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
STMDT12_C45790  anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
STMDT12_C02090  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
STMDT12_C23530  hypothetical protein [KO:K08722] [EC:3.1.3.89]
STMDT12_C37990  spoT; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
STMDT12_C25210  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
STMDT12_C40680  guanosine pentaphosphate phosphohydrolase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
STMDT12_C30090  relA; GDP/GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
STMDT12_C40890  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
STMDT12_C44950  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
STMDT12_C14770  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
STMDT12_C20340  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
STMDT12_C30210  lysine decarboxylase family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
STMDT12_C45310  cpdB; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
STMDT12_C05510  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
STMDT12_C30060  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
STMDT12_C32390  cyclic 3',5'-adenosine monophosphate phosphodiesterase [KO:K03651] [EC:3.1.4.53]
STMDT12_C38870  protein icc [KO:K03651] [EC:3.1.4.53]
STMDT12_C00890  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
STMDT12_C29820  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
STMDT12_C29830  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
STMDT12_C29840  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
STMDT12_C11160  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
STMDT12_C05870  allantoinase [KO:K01466] [EC:3.5.2.5]
STMDT12_C05910  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
STMDT12_C05900  hypothetical protein [KO:K14977] [EC:3.5.3.26]
STMDT12_C05800  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
STMDT12_C05920  ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
STMDT12_C05960  carbamate kinase [KO:K00926] [EC:2.7.2.2]
STMDT12_C45940  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sem00030  Pentose phosphate pathway
sem00220  Arginine biosynthesis
sem00250  Alanine, aspartate and glutamate metabolism
sem00260  Glycine, serine and threonine metabolism
sem00340  Histidine metabolism
sem00630  Glyoxylate and dicarboxylate metabolism
sem00730  Thiamine metabolism
sem00740  Riboflavin metabolism
sem00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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