KEGG   PATHWAY: sgoe00230
Entry
sgoe00230                   Pathway                                
Name
Purine metabolism - Scandinavium goeteborgense
Class
Metabolism; Nucleotide metabolism
Pathway map
sgoe00230  Purine metabolism
sgoe00230

Module
sgoe_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sgoe00230]
sgoe_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sgoe00230]
sgoe_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sgoe00230]
sgoe_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sgoe00230]
sgoe_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sgoe00230]
sgoe_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:sgoe00230]
sgoe_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:sgoe00230]
Other DBs
GO: 0006163 0042278
Organism
Scandinavium goeteborgense [GN:sgoe]
Gene
A8O29_011700  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
A8O29_003970  nudF; ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
A8O29_002220  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
A8O29_019625  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
A8O29_016145  pgm; alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
A8O29_009840  prs; ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
A8O29_006940  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
A8O29_021280  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
A8O29_006315  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
A8O29_009255  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
A8O29_006055  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
A8O29_006320  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
A8O29_017255  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
A8O29_017250  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
A8O29_006420  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
A8O29_014035  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
A8O29_021275  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
A8O29_017540  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
A8O29_017475  bifunctional UDP-sugar hydrolase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
A8O29_005080  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
A8O29_016210  nagD; ribonucleotide monophosphatase NagD [KO:K02566] [EC:3.1.3.5]
A8O29_002210  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
A8O29_017490  inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
A8O29_019815  xapA; xanthosine phosphorylase [KO:K03783] [EC:2.4.2.1]
A8O29_019620  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
A8O29_018050  ppnP; pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
A8O29_010380  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
A8O29_005880  pgeF; polyphenol oxidase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
A8O29_018925  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
A8O29_006260  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
A8O29_006205  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
A8O29_019575  yjjX; inosine/xanthosine triphosphatase [KO:K01529] [EC:3.6.1.73]
A8O29_004260  XTP/dITP diphosphatase [KO:K01519] [EC:3.6.1.66]
A8O29_018330  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
A8O29_011280  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
A8O29_011285  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
A8O29_018205  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
A8O29_018200  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
A8O29_018195  paoA; aldehyde dehydrogenase iron-sulfur subunit [KO:K13483]
A8O29_006265  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
A8O29_019085  GMP reductase [KO:K00364] [EC:1.7.1.7]
A8O29_011275  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
A8O29_001025  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
A8O29_005315  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
A8O29_007250  nrdA; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
A8O29_005310  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
A8O29_007245  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
A8O29_020090  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
A8O29_018790  dgt; dGTPase [KO:K01129] [EC:3.1.5.1]
A8O29_007055  yfbR; 5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
A8O29_005480  HD family hydrolase [KO:K06952] [EC:3.1.3.89]
A8O29_001015  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
A8O29_021825  gppA; guanosine-5'-triphosphate,3'-diphosphate diphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
A8O29_006305  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
A8O29_004985  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
A8O29_021680  cyaA; class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
A8O29_020445  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
A8O29_010635  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
A8O29_008335  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
A8O29_004925  LOG family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
A8O29_020290  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
A8O29_017500  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
A8O29_004990  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
A8O29_003980  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
A8O29_019345  apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [KO:K01525] [EC:3.6.1.41]
A8O29_005050  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
A8O29_005045  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
A8O29_005040  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
A8O29_012155  hpxO; FAD-dependent urate hydroxylase HpxO [KO:K16839] [EC:1.14.13.113]
A8O29_010795  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
A8O29_018450  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
A8O29_018495  hpxA; allantoin racemase [KO:K16841] [EC:5.1.99.3]
A8O29_018490  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
A8O29_018455  hpxK; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
A8O29_018460  alanine--glyoxylate aminotransferase family protein [KO:K00839] [EC:2.6.1.112]
A8O29_003865  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
A8O29_003870  urease subunit beta [KO:K01429] [EC:3.5.1.5]
A8O29_003875  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
A8O29_018480  AtzE family amidohydrolase [KO:K22601] [EC:2.1.3.5]
A8O29_018470  gamma-glutamyltransferase family protein [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sgoe00030  Pentose phosphate pathway
sgoe00220  Arginine biosynthesis
sgoe00250  Alanine, aspartate and glutamate metabolism
sgoe00260  Glycine, serine and threonine metabolism
sgoe00340  Histidine metabolism
sgoe00630  Glyoxylate and dicarboxylate metabolism
sgoe00730  Thiamine metabolism
sgoe00740  Riboflavin metabolism
sgoe00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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