KEGG   PATHWAY: vaq00230
Entry
vaq00230                    Pathway                                
Name
Purine metabolism - Vibrio aquimaris
Class
Metabolism; Nucleotide metabolism
Pathway map
vaq00230  Purine metabolism
vaq00230

Module
vaq_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:vaq00230]
vaq_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:vaq00230]
vaq_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:vaq00230]
vaq_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:vaq00230]
vaq_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:vaq00230]
vaq_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:vaq00230]
vaq_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:vaq00230]
Other DBs
GO: 0006163 0042278
Organism
Vibrio aquimaris [GN:vaq]
Gene
FIV01_11935  nudF1; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
FIV01_14760  nudF2; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
FIV01_00620  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
FIV01_10945  pgm; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
FIV01_04000  prs; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
FIV01_10505  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
FIV01_13645  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
FIV01_03435  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
FIV01_03365  purL; Phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
FIV01_03440  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
FIV01_00340  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
FIV01_00345  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
FIV01_07955  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
FIV01_06040  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
FIV01_13640  purH; Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
FIV01_10280  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
FIV01_18625  pyrE2; Orotate phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
FIV01_16160  NAD 5'-nucleotidase precursor [KO:K01081] [EC:3.1.3.5]
FIV01_04045  yfkN; Trifunctional nucleotide phosphoesterase protein YfkN precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
FIV01_12450  surE; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
FIV01_06055  gsk1; Inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
FIV01_15425  gsk2; Inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
FIV01_11530  deoD1; Purine nucleoside phosphorylase DeoD-type 1 [KO:K03784] [EC:2.4.2.1]
FIV01_17735  deoD2; Purine nucleoside phosphorylase DeoD-type 1 [KO:K03784] [EC:2.4.2.1]
FIV01_02770  yfiH; Laccase domain protein YfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
FIV01_12305  hpt; Hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
FIV01_03165  guaB2; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
FIV01_02880  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
FIV01_02735  Non-canonical purine NTP phosphatase [KO:K01529] [EC:3.6.1.73]
FIV01_01935  rdgB; dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
FIV01_11325  gpt; Xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
FIV01_18795  hcrC; 4-hydroxybenzoyl-CoA reductase subunit gamma [KO:K13481] [EC:1.17.1.4]
FIV01_18790  pucD; putative xanthine dehydrogenase subunit D [KO:K13482] [EC:1.17.1.4]
FIV01_03170  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
FIV01_08085  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
FIV01_15080  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
FIV01_18780  guaD; Guanine deaminase [KO:K01487] [EC:3.5.4.3]
FIV01_00650  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
FIV01_08045  nrdA; Ribonucleoside-diphosphate reductase 1 subunit alpha [KO:K00525] [EC:1.17.4.1]
FIV01_08050  nrdB; Ribonucleoside-diphosphate reductase 1 subunit beta [KO:K00526] [EC:1.17.4.1]
FIV01_15395  nrdD; Anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
FIV01_09720  dgt; Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
FIV01_09690  yfbR; 5'-deoxynucleotidase YfbR [KO:K08722] [EC:3.1.3.89]
FIV01_00640  spoT; Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
FIV01_03025  ppx; Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
FIV01_14040  gppA; Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
FIV01_02415  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
FIV01_13945  cyaA; Adenylate cyclase [KO:K05851] [EC:4.6.1.1]
FIV01_13395  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
FIV01_15860  Adenine deaminase [KO:K01488] [EC:3.5.4.4]
FIV01_10795  ygdH; LOG family protein YgdH [KO:K06966] [EC:3.2.2.10 3.2.2.-]
FIV01_09725  Adenine deaminase [KO:K21053] [EC:3.5.4.2]
FIV01_13190  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
FIV01_03745  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
FIV01_02420  mazG; Nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
FIV01_11045  cpdA1; 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
FIV01_11925  cpdA2; 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
FIV01_12560  apaH; Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [KO:K01525] [EC:3.6.1.41]
FIV01_13165  cysC; Adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
FIV01_13175  cysN; Sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
FIV01_13180  cysD; Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
FIV01_18650  pucM; 5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
FIV01_18745  pucL; Uric acid degradation bifunctional protein PucL [KO:K13485] [EC:4.1.1.97]
FIV01_18740  pgdA; Peptidoglycan deacetylase [KO:K16842] [EC:3.5.2.5]
FIV01_18750  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
FIV01_18755  allA; Ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
FIV01_13520  arcC1; Carbamate kinase 1 [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
vaq00030  Pentose phosphate pathway
vaq00220  Arginine biosynthesis
vaq00250  Alanine, aspartate and glutamate metabolism
vaq00260  Glycine, serine and threonine metabolism
vaq00340  Histidine metabolism
vaq00630  Glyoxylate and dicarboxylate metabolism
vaq00730  Thiamine metabolism
vaq00740  Riboflavin metabolism
vaq00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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