KEGG   PATHWAY: vle00230
Entry
vle00230                    Pathway                                
Name
Purine metabolism - Vibrio lentus
Class
Metabolism; Nucleotide metabolism
Pathway map
vle00230  Purine metabolism
vle00230

Module
vle_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:vle00230]
vle_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:vle00230]
vle_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:vle00230]
vle_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:vle00230]
vle_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:vle00230]
vle_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:vle00230]
vle_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:vle00230]
Other DBs
GO: 0006163 0042278
Organism
Vibrio lentus [GN:vle]
Gene
ISX51_18395  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
ISX51_09150  nudF; ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
ISX51_00850  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
ISX51_04505  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
ISX51_05645  pgm; phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [KO:K01835] [EC:5.4.2.2]
ISX51_10770  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ISX51_05930  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
ISX51_02985  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
ISX51_05305  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
ISX51_13965  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
ISX51_10360  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
ISX51_05310  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
ISX51_01655  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
ISX51_01660  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
ISX51_07665  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
ISX51_12525  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
ISX51_02980  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
ISX51_05955  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
ISX51_19160  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
ISX51_10815  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA [KO:K11751] [EC:3.1.3.5 3.6.1.45]
ISX51_03840  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
ISX51_19270  inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
ISX51_12545  inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
ISX51_04510  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
ISX51_13690  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
ISX51_16355  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
ISX51_23435  pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
ISX51_09785  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
ISX51_04110  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
ISX51_10140  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
ISX51_10015  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
ISX51_09750  yjjX; inosine/xanthosine triphosphatase [KO:K01529] [EC:3.6.1.73]
ISX51_03530  XTP/dITP diphosphatase [KO:K01519] [EC:3.6.1.66]
ISX51_04825  tet(34); oxytetracycline resistance phosphoribosyltransferase domain-containing protein Tet(34) [KO:K00769] [EC:2.4.2.22]
ISX51_16020  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
ISX51_16015  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
ISX51_10145  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
ISX51_17405  GMP reductase [KO:K00364] [EC:1.7.1.7]
ISX51_16005  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
ISX51_00790  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
ISX51_07365  nrdA; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
ISX51_07360  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
ISX51_18650  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
ISX51_11550  deoxyguanosinetriphosphate triphosphohydrolase family protein [KO:K01129] [EC:3.1.5.1]
ISX51_11555  yfbR; 5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
ISX51_00800  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
ISX51_01860  gppA; guanosine-5'-triphosphate,3'-diphosphate diphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ISX51_09865  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ISX51_03800  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
ISX51_03155  class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
ISX51_00120  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
ISX51_14390  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
ISX51_22365  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
ISX51_04955  ppnN; nucleotide 5'-monophosphate nucleosidase PpnN [KO:K06966] [EC:3.2.2.10 3.2.2.-]
ISX51_19660  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
ISX51_04795  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
ISX51_02215  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
ISX51_16580  5'-nucleotidase C-terminal domain-containing protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
ISX51_05565  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
ISX51_03805  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
ISX51_09160  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
ISX51_13725  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
ISX51_08895  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
ISX51_02195  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
ISX51_02205  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
ISX51_02210  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
ISX51_15930  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
ISX51_15940  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
ISX51_15935  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
ISX51_15945  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
ISX51_15950  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
ISX51_10110  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
ISX51_10105  urease subunit beta [KO:K01429] [EC:3.5.1.5]
ISX51_10100  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
ISX51_22100  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
ISX51_22980  carbamate kinase [KO:K00926] [EC:2.7.2.2]
ISX51_02860  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
vle00030  Pentose phosphate pathway
vle00220  Arginine biosynthesis
vle00250  Alanine, aspartate and glutamate metabolism
vle00260  Glycine, serine and threonine metabolism
vle00340  Histidine metabolism
vle00630  Glyoxylate and dicarboxylate metabolism
vle00730  Thiamine metabolism
vle00740  Riboflavin metabolism
vle00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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