KEGG   PATHWAY: vsh00230
Entry
vsh00230                    Pathway                                
Name
Purine metabolism - Vibrio mediterranei
Class
Metabolism; Nucleotide metabolism
Pathway map
vsh00230  Purine metabolism
vsh00230

Module
vsh_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:vsh00230]
vsh_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:vsh00230]
vsh_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:vsh00230]
vsh_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:vsh00230]
vsh_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:vsh00230]
vsh_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:vsh00230]
vsh_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:vsh00230]
Other DBs
GO: 0006163 0042278
Organism
Vibrio mediterranei [GN:vsh]
Gene
BSZ05_04075  nudF; ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BSZ05_23365  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BSZ05_18970  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BSZ05_07240  ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
BSZ05_09740  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
BSZ05_09985  phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
BSZ05_10685  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BSZ05_11525  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BSZ05_07290  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BSZ05_02705  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BSZ05_14320  phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
BSZ05_02900  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
BSZ05_02700  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BSZ05_06075  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
BSZ05_06070  5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
BSZ05_15825  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BSZ05_11935  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BSZ05_07295  bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BSZ05_11550  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BSZ05_22185  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
BSZ05_10730  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
BSZ05_03875  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BSZ05_21700  inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
BSZ05_11950  inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
BSZ05_25585  purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
BSZ05_09745  purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
BSZ05_24855  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
BSZ05_03370  multi-copper polyphenol oxidoreductase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BSZ05_04115  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BSZ05_18125  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BSZ05_03085  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
BSZ05_03145  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BSZ05_03405  inosine/xanthosine triphosphatase [KO:K01529] [EC:3.6.1.73]
BSZ05_04285  non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
BSZ05_02340  xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
BSZ05_13555  xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
BSZ05_13550  xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
BSZ05_03080  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
BSZ05_22900  GMP reductase [KO:K00364] [EC:1.7.1.7]
BSZ05_21630  guanine deaminase [KO:K01487] [EC:3.5.4.3]
BSZ05_13540  guanine deaminase [KO:K01487] [EC:3.5.4.3]
BSZ05_05375  guanylate kinase [KO:K00942] [EC:2.7.4.8]
BSZ05_12825  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
BSZ05_12820  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
BSZ05_22370  anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
BSZ05_11065  dGTPase [KO:K01129] [EC:3.1.5.1]
BSZ05_11070  5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
BSZ05_05385  bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BSZ05_03285  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BSZ05_05885  guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BSZ05_08695  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
BSZ05_05790  adenylate cyclase [KO:K05851] [EC:4.6.1.1]
BSZ05_16410  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
BSZ05_07850  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
BSZ05_24930  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
BSZ05_10015  LOG family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
BSZ05_24830  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
BSZ05_08095  2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
BSZ05_02560  adenylate kinase [KO:K00939] [EC:2.7.4.3]
BSZ05_08700  nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
BSZ05_04065  3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
BSZ05_13190  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
BSZ05_09150  bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [KO:K01525] [EC:3.6.1.41]
BSZ05_08120  adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
BSZ05_08110  sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
BSZ05_08105  sulfate adenylyltransferase small subunit [KO:K00957] [EC:2.7.7.4]
BSZ05_13445  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BSZ05_13455  OHCU decarboxylase [KO:K13485] [EC:4.1.1.97]
BSZ05_13450  allantoinase [KO:K16842] [EC:3.5.2.5]
BSZ05_13460  allantoicase [KO:K01477] [EC:3.5.3.4]
BSZ05_20175  Zn-dependent hydrolase [KO:K02083] [EC:3.5.3.9]
BSZ05_13465  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
BSZ05_25075  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
BSZ05_25080  urease subunit beta [KO:K01429] [EC:3.5.1.5]
BSZ05_25085  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
BSZ05_21340  carbamate kinase [KO:K00926] [EC:2.7.2.2]
BSZ05_18620  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
vsh00030  Pentose phosphate pathway
vsh00220  Arginine biosynthesis
vsh00250  Alanine, aspartate and glutamate metabolism
vsh00260  Glycine, serine and threonine metabolism
vsh00340  Histidine metabolism
vsh00630  Glyoxylate and dicarboxylate metabolism
vsh00730  Thiamine metabolism
vsh00740  Riboflavin metabolism
vsh00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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