KEGG   PATHWAY: xma00564
Entry
xma00564                    Pathway                                
Name
Glycerophospholipid metabolism - Xiphophorus maculatus (southern platyfish)
Class
Metabolism; Lipid metabolism
Pathway map
xma00564  Glycerophospholipid metabolism
xma00564

Module
xma_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:xma00564]
xma_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:xma00564]
xma_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:xma00564]
Other DBs
GO: 0006650
Organism
Xiphophorus maculatus (southern platyfish) [GN:xma]
Gene
102231684  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
102222779  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like [KO:K00006] [EC:1.1.1.8]
102228568  gpd1; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
102225536  gpd2; glycerol-3-phosphate dehydrogenase, mitochondrial isoform X2 [KO:K00111] [EC:1.1.5.3]
102223435  gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
102232250  glycerol-3-phosphate acyltransferase 2, mitochondrial-like [KO:K00629] [EC:2.3.1.15]
102224451  glycerol-3-phosphate acyltransferase 4-like [KO:K13506] [EC:2.3.1.15]
102221260  gpat3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
102218245  gpat4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
102232784  glycerol-3-phosphate acyltransferase 3-like [KO:K13506] [EC:2.3.1.15]
102232433  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha-like isoform X2 [KO:K13509] [EC:2.3.1.51]
102237288  agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
102227356  agpat4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
102221155  agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
102232013  lclat1; lysocardiolipin acyltransferase 1 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
102224157  membrane-bound O-acyltransferase domain-containing protein 2-like [KO:K13517] [EC:2.3.1.51 2.3.1.-]
102219669  lysophospholipid acyltransferase 2-like [KO:K13517] [EC:2.3.1.51 2.3.1.-]
102227631  mboat1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
102223376  dihydroxyacetone phosphate acyltransferase-like [KO:K00649] [EC:2.3.1.42]
102217607  gnpat; dihydroxyacetone phosphate acyltransferase isoform X2 [KO:K00649] [EC:2.3.1.42]
102227889  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
102221892  phospholipid phosphatase 2-like [KO:K01080] [EC:3.1.3.4]
102231137  plpp3; phospholipid phosphatase 3 isoform X1 [KO:K01080] [EC:3.1.3.4]
102228703  plpp1; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
102232612  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
102233341  phospholipid phosphatase 3-like isoform X1 [KO:K01080] [EC:3.1.3.4]
102227106  plpp2; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
102228480  phospholipid phosphatase 3-like isoform X2 [KO:K01080] [EC:3.1.3.4]
102219360  phospholipid phosphatase 1-like [KO:K01080] [EC:3.1.3.4]
102221099  phosphatidate phosphatase LPIN1-like isoform X3 [KO:K15728] [EC:3.1.3.4]
102228278  lpin2; phosphatidate phosphatase LPIN2 [KO:K15728] [EC:3.1.3.4]
102223631  lpin1; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
102237852  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
102228807  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
102228001  plpp5; phospholipid phosphatase 5 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
102217276  plpp4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
102235784  dgkz; diacylglycerol kinase zeta isoform X2 [KO:K00901] [EC:2.7.1.107]
102235891  dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
102216842  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
102225104  diacylglycerol kinase alpha isoform X1 [KO:K00901] [EC:2.7.1.107]
102231869  diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
102218911  dgkd; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
102223813  dgkh; diacylglycerol kinase eta isoform X3 [KO:K00901] [EC:2.7.1.107]
102218493  dgkq; diacylglycerol kinase theta isoform X2 [KO:K00901] [EC:2.7.1.107]
102221199  diacylglycerol kinase alpha-like [KO:K00901] [EC:2.7.1.107]
102229867  dgkg; diacylglycerol kinase gamma isoform X1 [KO:K00901] [EC:2.7.1.107]
102220024  diacylglycerol kinase eta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
102235171  chpt1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
102225565  cept1; choline/ethanolaminephosphotransferase 1 isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
102225016  phospholipase D1-like [KO:K01115] [EC:3.1.4.4]
102217553  phospholipase D1-like [KO:K01115] [EC:3.1.4.4]
102220287  pld1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
102223943  phospholipase D3-like isoform X1 [KO:K16860] [EC:3.1.4.4]
102218738  pld3; phospholipase D3 isoform X2 [KO:K16860] [EC:3.1.4.4]
102232210  pld4; phospholipase D4 [KO:K16860] [EC:3.1.4.4]
102230865  phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
102232521  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
102234505  pla2g12a; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
102233490  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
102218967  group XIIB secretory phospholipase A2-like protein [KO:K01047] [EC:3.1.1.4]
102223321  group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
102220693  group 3 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
102219264  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
102219520  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
102235934  group 3 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
111611909  proca1; protein PROCA1 [KO:K01047] [EC:3.1.1.4]
102235312  pla2g4a; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
111611546  pla2g4c; cytosolic phospholipase A2 gamma isoform X1 [KO:K16342] [EC:3.1.1.4]
102230844  pla2g6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
102223452  plb1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
102225455  phospholipase B1, membrane-associated-like isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
111611425  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
102221396  HRAS-like suppressor 3 isoform X1 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
102228999  HRAS-like suppressor 3 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
102230685  retinoic acid receptor responder protein 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
102235351  phospholipid-metabolizing enzyme A-C1-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
102233875  lysophosphatidylcholine acyltransferase 1-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]
102226601  lpcat2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
102224007  lysophosphatidylcholine acyltransferase 1 isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
102224962  lpcat4; lysophospholipid acyltransferase LPCAT4 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
102235292  lpcat3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
102226222  lypla1; acyl-protein thioesterase 1 [KO:K06128] [EC:3.1.1.5]
102219714  group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
102234364  lypla2; acyl-protein thioesterase 2 isoform X2 [KO:K06130] [EC:3.1.1.5]
102217162  patatin-like phospholipase domain-containing protein 7 [KO:K14676] [EC:3.1.1.5]
102219069  pnpla6; neuropathy target esterase isoform X7 [KO:K14676] [EC:3.1.1.5]
102236154  pnpla7; patatin-like phospholipase domain-containing protein 7 isoform X3 [KO:K14676] [EC:3.1.1.5]
102224753  gpcpd1; glycerophosphocholine phosphodiesterase GPCPD1 [KO:K18695] [EC:3.1.4.2]
102218840  choline O-acetyltransferase-like [KO:K00623] [EC:2.3.1.6]
102227259  chat; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
102225183  ache; acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
102223293  cAMP-regulated D2 protein-like [KO:K01049] [EC:3.1.1.7]
102230116  choline/ethanolamine kinase [KO:K14156] [EC:2.7.1.32 2.7.1.82]
102225161  choline kinase alpha isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
102220236  phospho1; phosphoethanolamine/phosphocholine phosphatase isoform X2 [KO:K06124] [EC:3.1.3.75]
102227979  probable phosphatase phospho1 [KO:K06124] [EC:3.1.3.75]
102223556  choline-phosphate cytidylyltransferase B-like [KO:K00968] [EC:2.7.7.15]
102228138  pcyt1b; choline-phosphate cytidylyltransferase B isoform X2 [KO:K00968] [EC:2.7.7.15]
102233739  choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
102223572  selenoi; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
102226641  ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
102217092  etnk1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
102222711  ethanolamine kinase 1-like isoform X1 [KO:K00894] [EC:2.7.1.82]
102220329  ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
102230469  pcyt2; ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
102222707  phosphoethanolamine N-methyltransferase 3-like isoform X1 [KO:K05929] [EC:2.1.1.103]
102219957  etnppl; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
102221066  pemt; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
102225977  phosphatidate cytidylyltransferase 2 isoform X2 [KO:K00981] [EC:2.7.7.41]
102230574  phosphatidate cytidylyltransferase 1-like [KO:K00981] [EC:2.7.7.41]
102232463  pla1a; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
102229605  phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
102225171  phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
102221675  ptdss2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
102235102  pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
102232327  pgs1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial isoform X1 [KO:K00995] [EC:2.7.8.5]
102218243  taz; tafazzin isoform X2 [KO:K13511] [EC:2.3.1.-]
102221120  lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
102230947  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
102226639  mboat7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
xma00010  Glycolysis / Gluconeogenesis
xma00260  Glycine, serine and threonine metabolism
xma00561  Glycerolipid metabolism
xma00562  Inositol phosphate metabolism
xma00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
xma00565  Ether lipid metabolism
xma00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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