KEGG   PATHWAY: pcoq04612
Entry
pcoq04612                   Pathway                                
Name
Antigen processing and presentation - Propithecus coquereli (Coquerel's sifaka)
Class
Organismal Systems; Immune system
Pathway map
pcoq04612  Antigen processing and presentation
pcoq04612

Other DBs
GO: 0019885 0019886 0042591
Organism
Propithecus coquereli (Coquerel's sifaka) [GN:pcoq]
Gene
105805024  CD4; T-cell surface glycoprotein CD4 [KO:K06454]
105806269  [KO:K08057]
105806470  HSPA6; heat shock 70 kDa protein 6 [KO:K03283]
105806582  HSPA5; 78 kDa glucose-regulated protein [KO:K09490] [EC:3.6.4.10]
105807468  HSP90AB1; heat shock protein HSP 90-beta isoform X1 [KO:K04079]
105807492  NFYA; nuclear transcription factor Y subunit alpha isoform X1 [KO:K08064]
105807890  CALR; calreticulin [KO:K08057]
105808396  IFNG; interferon gamma [KO:K04687]
105808869  [KO:K04079]
105809396  [KO:K07980]
105809486  [KO:K07980]
105809492  [KO:K07980]
105810125  RFXAP; regulatory factor X-associated protein [KO:K08063]
105810148  [KO:K06752]
105810260  CD8B; T-cell surface glycoprotein CD8 beta chain [KO:K06459]
105810265  CD8A; T-cell surface glycoprotein CD8 alpha chain [KO:K06458]
105810840  HSPA8; heat shock cognate 71 kDa protein [KO:K03283]
105811637  CTSB; cathepsin B [KO:K01363] [EC:3.4.22.1]
105812179  [KO:K08065]
105812334  NFYC; nuclear transcription factor Y subunit gamma isoform X1 [KO:K08066]
105812585  HSP90AA1; heat shock protein HSP 90-alpha [KO:K04079]
105812739  PSME2; proteasome activator complex subunit 2 [KO:K06697]
105812740  PSME1; proteasome activator complex subunit 1 [KO:K06696]
105813163  CIITA; MHC class II transactivator isoform X1 [KO:K08060] [EC:2.7.11.1]
105814175  [KO:K10784]
105814384  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
105814533  B2M; beta-2-microglobulin [KO:K08055]
105815115  NFYB; nuclear transcription factor Y subunit beta [KO:K08065]
105815823  [KO:K06541]
105816034  HSPA4; heat shock 70 kDa protein 4 [KO:K09489]
105816430  CTSV; cathepsin L2 [KO:K01365] [EC:3.4.22.15]
105816651  [KO:K24234]
105816652  [KO:K06541]
105816655  [KO:K06516]
105817268  [KO:K06751]
105817288  [KO:K06751]
105817290  [KO:K06751]
105817294  [KO:K06751]
105817835  [KO:K06752]
105817846  [KO:K06751]
105817877  [KO:K03283]
105817878  [KO:K03283]
105817879  HSPA1L; heat shock 70 kDa protein 1-like [KO:K03283]
105817905  TNF; tumor necrosis factor isoform X1 [KO:K03156]
105817910  [KO:K06751]
105817913  [KO:K06752]
105818175  RFXANK; DNA-binding protein RFXANK isoform X1 [KO:K08062]
105818190  IFI30; gamma-interferon-inducible lysosomal thiol reductase [KO:K08059]
105819860  HSPA2; heat shock-related 70 kDa protein 2 [KO:K26598]
105820208  PSME3; proteasome activator complex subunit 3 [KO:K06698]
105820278  LGMN; legumain [KO:K01369] [EC:3.4.22.34]
105821569  CD74; HLA class II histocompatibility antigen gamma chain isoform X1 [KO:K06505]
105821685  TAPBP; tapasin [KO:K08058]
105821894  RFX5; DNA-binding protein RFX5 isoform X1 [KO:K08061]
105821963  CTSS; cathepsin S [KO:K01368] [EC:3.4.22.27]
105822117  [KO:K06541]
105822404  CTSL; cathepsin L1 [KO:K01365] [EC:3.4.22.15]
105823264  CANX; calnexin [KO:K08054]
105823945  CREB1; cyclic AMP-responsive element-binding protein 1 [KO:K05870]
105823953  KLRC4; NKG2-F type II integral membrane protein [KO:K24234]
105824372  [KO:K06752]
105824378  TAP1; antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
105824379  TAP2; antigen peptide transporter 2 isoform X1 [KO:K05654] [EC:7.4.2.14]
105824381  [KO:K06752]
105824383  [KO:K06752]
105824384  [KO:K06752]
105824385  [KO:K06752]
105824386  [KO:K06752]
105824388  [KO:K06752]
105824389  [KO:K06752]
105826384  [KO:K06541]
105826387  [KO:K06541]
105826775  [KO:K24234]
Reference
PMID:15771591
  Authors
Trombetta ES, Mellman I.
  Title
Cell biology of antigen processing in vitro and in vivo.
  Journal
Annu Rev Immunol 23:975-1028 (2005)
DOI:10.1146/annurev.immunol.22.012703.104538
Reference
PMID:15814328
  Authors
Inaba K, Inaba M.
  Title
Antigen recognition and presentation by dendritic cells.
  Journal
Int J Hematol 81:181-7 (2005)
DOI:10.1532/IJH97.04200
Reference
PMID:11905820
  Authors
Heath WR, Carbone FR.
  Title
Cross-presentation in viral immunity and self-tolerance.
  Journal
Nat Rev Immunol 1:126-34 (2001)
DOI:10.1038/35100512
Reference
PMID:15304636
  Authors
Abele R, Tampe R.
  Title
The ABCs of immunology: structure and function of TAP, the transporter associated with antigen processing.
  Journal
Physiology (Bethesda) 19:216-24 (2004)
DOI:10.1152/physiol.00002.2004
Reference
PMID:16200082
  Authors
Reith W, LeibundGut-Landmann S, Waldburger JM.
  Title
Regulation of MHC class II gene expression by the class II transactivator.
  Journal
Nat Rev Immunol 5:793-806 (2005)
DOI:10.1038/nri1708
Reference
PMID:12776207
  Authors
Honey K, Rudensky AY.
  Title
Lysosomal cysteine proteases regulate antigen presentation.
  Journal
Nat Rev Immunol 3:472-82 (2003)
DOI:10.1038/nri1110
Reference
PMID:12974477
  Authors
Sercarz EE, Maverakis E.
  Title
Mhc-guided processing: binding of large antigen fragments.
  Journal
Nat Rev Immunol 3:621-9 (2003)
DOI:10.1038/nri1149
Reference
PMID:15224093
  Authors
Ackerman AL, Cresswell P.
  Title
Cellular mechanisms governing cross-presentation of exogenous antigens.
  Journal
Nat Immunol 5:678-84 (2004)
DOI:10.1038/ni1082
Reference
PMID:16181333
  Authors
Cresswell P, Ackerman AL, Giodini A, Peaper DR, Wearsch PA.
  Title
Mechanisms of MHC class I-restricted antigen processing and cross-presentation.
  Journal
Immunol Rev 207:145-57 (2005)
DOI:10.1111/j.0105-2896.2005.00316.x
Reference
PMID:15653312
  Authors
Zika E, Ting JP.
  Title
Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes.
  Journal
Curr Opin Immunol 17:58-64 (2005)
DOI:10.1016/j.coi.2004.11.008
Reference
PMID:11244040
  Authors
Reith W, Mach B.
  Title
The bare lymphocyte syndrome and the regulation of MHC expression.
  Journal
Annu Rev Immunol 19:331-73 (2001)
DOI:10.1146/annurev.immunol.19.1.331
Reference
PMID:15745856
  Authors
Lizee G, Basha G, Jefferies WA.
  Title
Tails of wonder: endocytic-sorting motifs key for exogenous antigen presentation.
  Journal
Trends Immunol 26:141-9 (2005)
DOI:10.1016/j.it.2005.01.005
Reference
PMID:15224094
  Authors
Watts C.
  Title
The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules.
  Journal
Nat Immunol 5:685-92 (2004)
DOI:10.1038/ni1088
Reference
PMID:15653315
  Authors
Kaufmann SH, Schaible UE.
  Title
Antigen presentation and recognition in bacterial infections.
  Journal
Curr Opin Immunol 17:79-87 (2005)
DOI:10.1016/j.coi.2004.12.004
Reference
PMID:20010787
  Authors
Groettrup M, Kirk CJ, Basler M
  Title
Proteasomes in immune cells: more than peptide producers?
  Journal
Nat Rev Immunol 10:73-8 (2010)
DOI:10.1038/nri2687
Related
pathway
pcoq03050  Proteasome
pcoq04650  Natural killer cell mediated cytotoxicity
pcoq04660  T cell receptor signaling pathway
KO pathway
ko04612   

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