KEGG   PATHWAY: pez00230
Entry
pez00230                    Pathway                                
Name
Purine metabolism - Pseudomonas eucalypticola
Class
Metabolism; Nucleotide metabolism
Pathway map
pez00230  Purine metabolism
pez00230

Module
pez_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pez00230]
pez_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pez00230]
pez_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pez00230]
pez_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pez00230]
pez_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pez00230]
pez_M00546  Purine degradation, xanthine => urea [PATH:pez00230]
pez_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pez00230]
pez_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pez00230]
Other DBs
GO: 0006163 0042278
Organism
Pseudomonas eucalypticola [GN:pez]
Gene
HWQ56_01155  [KO:K03816] [EC:2.4.2.22]
HWQ56_01290  [KO:K05851] [EC:4.6.1.1]
HWQ56_01415  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
HWQ56_01685  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
HWQ56_01690  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
HWQ56_02570  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
HWQ56_02630  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
HWQ56_02640  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
HWQ56_02815  [KO:K01939] [EC:6.3.4.4]
HWQ56_03025  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
HWQ56_03030  [KO:K01429] [EC:3.5.1.5]
HWQ56_03045  [KO:K01430] [EC:3.5.1.5]
HWQ56_03155  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
HWQ56_03160  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
HWQ56_03440  [KO:K21053] [EC:3.5.4.2]
HWQ56_04510  [KO:K00948] [EC:2.7.6.1]
HWQ56_04645  [KO:K00760] [EC:2.4.2.8]
HWQ56_05655  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
HWQ56_05775  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
HWQ56_05780  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
HWQ56_05835  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
HWQ56_05885  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
HWQ56_06220  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
HWQ56_06820  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
HWQ56_06825  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
HWQ56_07655  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
HWQ56_07840  [KO:K01483] [EC:4.3.2.3]
HWQ56_07845  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
HWQ56_07850  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
HWQ56_07855  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
HWQ56_07860  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
HWQ56_07885  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
HWQ56_07895  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
HWQ56_07900  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
HWQ56_08020  [KO:K00759] [EC:2.4.2.7]
HWQ56_08480  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
HWQ56_08995  [KO:K01129] [EC:3.1.5.1]
HWQ56_09585  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
HWQ56_10910  [KO:K16856] [EC:4.3.2.3]
HWQ56_11695  hpxO; FAD-dependent urate hydroxylase HpxO [KO:K16839] [EC:1.14.13.113]
HWQ56_12150  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
HWQ56_12370  [KO:K01835] [EC:5.4.2.2]
HWQ56_12865  [KO:K13483]
HWQ56_12870  [KO:K11178] [EC:1.17.1.4]
HWQ56_12875  [KO:K11177] [EC:1.17.1.4]
HWQ56_13035  [KO:K06966] [EC:3.2.2.10 3.2.2.-]
HWQ56_16765  [KO:K16841] [EC:5.1.99.3]
HWQ56_17430  [KO:K22879] [EC:1.14.13.113]
HWQ56_18345  [KO:K01081] [EC:3.1.3.5]
HWQ56_22000  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
HWQ56_22510  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
HWQ56_22515  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
HWQ56_22645  [KO:K00525] [EC:1.17.4.1]
HWQ56_22650  [KO:K00526] [EC:1.17.4.1]
HWQ56_23090  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
HWQ56_24145  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
HWQ56_24150  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
HWQ56_24705  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
HWQ56_24915  [KO:K01081] [EC:3.1.3.5]
HWQ56_25050  [KO:K11177] [EC:1.17.1.4]
HWQ56_25055  [KO:K11178] [EC:1.17.1.4]
HWQ56_25060  [KO:K13483]
HWQ56_25270  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
HWQ56_26200  [KO:K01525] [EC:3.6.1.41]
HWQ56_27125  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
HWQ56_27985  [KO:K15778] [EC:5.4.2.8 5.4.2.2]
HWQ56_28020  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
HWQ56_28030  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
HWQ56_28335  [KO:K01589] [EC:6.3.4.18]
HWQ56_28340  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pez00030  Pentose phosphate pathway
pez00220  Arginine biosynthesis
pez00250  Alanine, aspartate and glutamate metabolism
pez00260  Glycine, serine and threonine metabolism
pez00340  Histidine metabolism
pez00630  Glyoxylate and dicarboxylate metabolism
pez00730  Thiamine metabolism
pez00740  Riboflavin metabolism
pez00790  Folate biosynthesis
KO pathway
ko00230   

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