KEGG   PATHWAY: pic00230
Entry
pic00230                    Pathway                                
Name
Purine metabolism - Scheffersomyces stipitis
Class
Metabolism; Nucleotide metabolism
Pathway map
pic00230  Purine metabolism
pic00230

Module
pic_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:pic00230]
pic_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pic00230]
pic_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pic00230]
pic_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pic00230]
pic_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pic00230]
Other DBs
GO: 0006163 0042278
Organism
Scheffersomyces stipitis [GN:pic]
Gene
PICST_29461  APT1; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
PICST_29856  RNR1.1; ribonucleoside-diphosphate reductase alpha subunit [KO:K10807] [EC:1.17.4.1]
PICST_31509  [KO:K07127] [EC:3.5.2.17]
PICST_32593  PHO3; acid phosphatase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
PICST_34307  KPR4; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
PICST_34864  PUR3; Phosphoribosylglycinamide formyltransferase (GART) (GAR transformylase) (5'-phosphoribosylglycinamide transformylase) [KO:K00601] [EC:2.1.2.2]
PICST_34891  ALN1; Allantoinase [KO:K01466] [EC:3.5.2.5]
PICST_36448  GAH1; guanine deaminase (Guanase) (Guanine aminase) (Guanine aminohydrolase) (GAH) [KO:K01487] [EC:3.5.4.3]
PICST_38342  ISN1; IMP 5'-nucleotidase [KO:K18550] [EC:3.1.3.99 3.1.3.-]
PICST_39137  FAP7; Predicted nucleotide kinase/nuclear protein involved oxidative stress response [KO:K18532] [EC:2.7.4.3]
PICST_40781  URO1; peroxisomal urate oxidase [KO:K00365] [EC:1.7.3.3]
PICST_40926  AMD1; AMP deaminase [KO:K01490] [EC:3.5.4.6]
PICST_42834  [KO:K07023] [EC:3.1.3.89]
PICST_43701  DAL3; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
PICST_47650  PHO3.2; acid phosphatase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
PICST_48616  APA2; 5',5'''-P-1,P-4-tetraphosphate phosphorylase II (Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase) (AP-4-A phosphorylase) (AP,A phosphorylase) (ATP adenylyltransferase) [KO:K00988] [EC:2.7.7.5 2.7.7.53]
PICST_49451  PUR7; Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase) [KO:K01923] [EC:6.3.2.6]
PICST_53805  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
PICST_55822  DAL2; allantoinase [KO:K01477] [EC:3.5.3.4]
PICST_56209  HNT2; diadenosine polyphosphate hydrolase [KO:K01522] [EC:3.6.1.29]
PICST_57331  ADO1; adenosine kinase [KO:K00856] [EC:2.7.1.20]
PICST_59156  AAH1; adenine aminohydrolase (adenine deaminase) [KO:K21053] [EC:3.5.4.2]
PICST_63834  ADK2; Adenylate kinase 2 (mitochondrial GTP:AMP phosphotransferase) [KO:K00944] [EC:2.7.4.10]
PICST_65580  PRS1; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
PICST_65737  ADK1; Adenylate kinase (ATP-AMP transphosphorylase) [KO:K00939] [EC:2.7.4.3]
PICST_65804  [KO:K00088] [EC:1.1.1.205]
PICST_66107  PRS2; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
PICST_66841  HPT1; hypoxanthine guanine phosphoribosyltransferase [KO:K19836] [EC:2.4.2.8]
PICST_67440  CDC35; adenylate cyclase (ATP pyrophosphate-lyase) (Adenylyl cyclase) [KO:K01768] [EC:4.6.1.1]
PICST_67856  YNK1; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
PICST_68505  PUR92; Bifunctional purine biosynthesis protein ADE17 Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) IMP cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC) [KO:K00602] [EC:2.1.2.3 3.5.4.10]
PICST_70121  GUA1; GMP synthase [KO:K01951] [EC:6.3.5.2]
PICST_70259  RNR2; small subunit of ribonucleotide reductase [KO:K10808] [EC:1.17.4.1]
PICST_72675  GUK1; guanylate kinase (GUK1) [KO:K00942] [EC:2.7.4.8]
PICST_72696  HAM1; inosine triphosphate pyrophosphatase, putative / HAM1 family protein [KO:K01519] [EC:3.6.1.66]
PICST_75213  YND1; Yeast Nucleoside Diphosphatase [KO:K14642] [EC:3.6.1.5]
PICST_75451  MET3; Sulfate adenylyltransferase (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase) [KO:K00958] [EC:2.7.7.4]
PICST_75569  ADE6; 5'-phosphoribosylformyl glycinamidine synthetase [KO:K01952] [EC:6.3.5.3]
PICST_75662  RNR1.2; Ribonucleoside-diphosphate reductase large chain 1 [KO:K10807] [EC:1.17.4.1]
PICST_77218  PGM2; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
PICST_78248  PRS5; phosphoribosylpyrophosphate synthetase [KO:K00948] [EC:2.7.6.1]
PICST_78524  PPX1; exopolyphosphatase (ExopolyPase) (Metaphosphatase) [KO:K01514] [EC:3.6.1.11]
PICST_78660  [KO:K11788] [EC:6.3.4.13 6.3.3.1]
PICST_78788  ADE4; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
PICST_81265  ADE2; Phosphoribosylamidoimidazole-succinocarboxamide synthase [KO:K11808] [EC:4.1.1.21]
PICST_84281  CNA1; 3',5'-cyclic-nucleotide phosphodiesterase (PDEase) (3':5'-CNP) [KO:K01120] [EC:3.1.4.17]
PICST_84718  ADE13; 3-isopropylmalate dehydratase [KO:K01756] [EC:4.3.2.2]
PICST_85387  [KO:K01939] [EC:6.3.4.4]
PICST_85565  YND2; Yeast Nucleoside Diphosphatase [KO:K14642] [EC:3.6.1.5]
PICST_90976  KAP1; Adenylyl-sulfate kinase (APS kinase) (Adenosine-5'phosphosulfate kinase) (ATP adenosine-5'-phosphosulfate 3'-phosphotransferase) [KO:K00860] [EC:2.7.1.25]
PICST_91072  PGM3; Phosphoglucomutase/phosphomannomutase [KO:K01835] [EC:5.4.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pic00030  Pentose phosphate pathway
pic00220  Arginine biosynthesis
pic00250  Alanine, aspartate and glutamate metabolism
pic00260  Glycine, serine and threonine metabolism
pic00340  Histidine metabolism
pic00630  Glyoxylate and dicarboxylate metabolism
pic00730  Thiamine metabolism
pic00740  Riboflavin metabolism
pic00790  Folate biosynthesis
KO pathway
ko00230   

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