KEGG   PATHWAY: pmam00230
Entry
pmam00230                   Pathway                                
Name
Purine metabolism - Pseudomonas maumuensis
Class
Metabolism; Nucleotide metabolism
Pathway map
pmam00230  Purine metabolism
pmam00230

Module
pmam_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pmam00230]
pmam_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pmam00230]
pmam_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pmam00230]
pmam_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pmam00230]
pmam_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pmam00230]
pmam_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pmam00230]
pmam_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pmam00230]
Other DBs
GO: 0006163 0042278
Organism
Pseudomonas maumuensis [GN:pmam]
Gene
KSS90_22965  NUDIX domain-containing protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
KSS90_24295  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
KSS90_15385  pgm; phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [KO:K01835] [EC:5.4.2.2]
KSS90_24890  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
KSS90_04390  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
KSS90_18145  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
KSS90_22475  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
KSS90_06910  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
KSS90_05825  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
KSS90_05660  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
KSS90_06915  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
KSS90_25135  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
KSS90_25140  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
KSS90_06585  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
KSS90_10205  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
KSS90_22470  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
KSS90_08525  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
KSS90_11445  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
KSS90_06170  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
KSS90_10085  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
KSS90_24300  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
KSS90_08610  pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
KSS90_21970  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
KSS90_04485  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
KSS90_05630  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
KSS90_04950  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
KSS90_23880  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
KSS90_24785  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
KSS90_08400  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
KSS90_08395  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
KSS90_05635  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
KSS90_08385  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
KSS90_24945  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
KSS90_19460  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
KSS90_19465  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
KSS90_17845  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
KSS90_24975  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
KSS90_24515  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
KSS90_19335  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
KSS90_00730  class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
KSS90_22805  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
KSS90_03205  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
KSS90_15280  ppnN; nucleotide 5'-monophosphate nucleosidase PpnN [KO:K06966] [EC:3.2.2.10 3.2.2.-]
KSS90_03770  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
KSS90_06210  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
KSS90_19330  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
KSS90_22955  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
KSS90_02165  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
KSS90_21300  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
KSS90_03405  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
KSS90_21305  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
KSS90_08360  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
KSS90_08350  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
KSS90_08175  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
KSS90_08355  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
KSS90_11975  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
KSS90_08345  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
KSS90_14075  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
KSS90_14080  urease subunit beta [KO:K01429] [EC:3.5.1.5]
KSS90_14085  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
KSS90_05475  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pmam00030  Pentose phosphate pathway
pmam00220  Arginine biosynthesis
pmam00250  Alanine, aspartate and glutamate metabolism
pmam00260  Glycine, serine and threonine metabolism
pmam00340  Histidine metabolism
pmam00630  Glyoxylate and dicarboxylate metabolism
pmam00730  Thiamine metabolism
pmam00740  Riboflavin metabolism
pmam00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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