KEGG   PATHWAY: ppeg00230
Entry
ppeg00230                   Pathway                                
Name
Purine metabolism - Pseudomonas pergaminensis
Class
Metabolism; Nucleotide metabolism
Pathway map
ppeg00230  Purine metabolism
ppeg00230

Module
ppeg_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:ppeg00230]
ppeg_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ppeg00230]
ppeg_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ppeg00230]
ppeg_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ppeg00230]
ppeg_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ppeg00230]
ppeg_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:ppeg00230]
ppeg_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:ppeg00230]
Other DBs
GO: 0006163 0042278
Organism
Pseudomonas pergaminensis [GN:ppeg]
Gene
KUA23_01000  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
KUA23_01035  [KO:K01487] [EC:3.5.4.3]
KUA23_01350  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
KUA23_01355  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
KUA23_02470  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
KUA23_02535  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
KUA23_02545  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
KUA23_02680  [KO:K01939] [EC:6.3.4.4]
KUA23_02950  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
KUA23_02955  [KO:K01429] [EC:3.5.1.5]
KUA23_02970  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
KUA23_03050  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
KUA23_03055  [KO:K01429] [EC:3.5.1.5]
KUA23_03070  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
KUA23_03200  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
KUA23_03205  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
KUA23_03475  [KO:K21053] [EC:3.5.4.2]
KUA23_03720  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
KUA23_03875  [KO:K00948] [EC:2.7.6.1]
KUA23_04015  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
KUA23_04020  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
KUA23_04125  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
KUA23_04735  [KO:K00760] [EC:2.4.2.8]
KUA23_06280  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
KUA23_06570  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
KUA23_07420  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
KUA23_08380  ppnN; nucleotide 5'-monophosphate nucleosidase PpnN [KO:K06966] [EC:3.2.2.10 3.2.2.-]
KUA23_08890  [KO:K01081] [EC:3.1.3.5]
KUA23_09050  [KO:K01129] [EC:3.1.5.1]
KUA23_10300  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
KUA23_13075  [KO:K00526] [EC:1.17.4.1]
KUA23_13440  [KO:K01239] [EC:3.2.2.1]
KUA23_14830  pgm; phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [KO:K01835] [EC:5.4.2.2]
KUA23_17425  [KO:K03651] [EC:3.1.4.53]
KUA23_17995  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
KUA23_20280  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
KUA23_21240  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
KUA23_21245  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
KUA23_21250  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
KUA23_21255  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
KUA23_21260  [KO:K01483] [EC:4.3.2.3]
KUA23_21430  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
KUA23_21930  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
KUA23_21935  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
KUA23_21955  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
KUA23_21960  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
KUA23_22275  [KO:K00759] [EC:2.4.2.7]
KUA23_22375  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
KUA23_22380  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
KUA23_22390  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
KUA23_22630  [KO:K16841] [EC:5.1.99.3]
KUA23_23010  [KO:K00525] [EC:1.17.4.1]
KUA23_23330  [KO:K00526] [EC:1.17.4.1]
KUA23_24010  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
KUA23_24615  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
KUA23_24680  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
KUA23_24730  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
KUA23_24735  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
KUA23_24825  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
KUA23_26060  [KO:K11177] [EC:1.17.1.4]
KUA23_26065  [KO:K11178] [EC:1.17.1.4]
KUA23_26070  [KO:K13483]
KUA23_26280  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
KUA23_27285  [KO:K01525] [EC:3.6.1.41]
KUA23_28220  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
KUA23_28925  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
KUA23_29065  [KO:K05851] [EC:4.6.1.1]
KUA23_29175  [KO:K03816] [EC:2.4.2.22]
KUA23_29320  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
KUA23_29330  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
KUA23_29615  [KO:K01589] [EC:6.3.4.18]
KUA23_29620  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ppeg00030  Pentose phosphate pathway
ppeg00220  Arginine biosynthesis
ppeg00250  Alanine, aspartate and glutamate metabolism
ppeg00260  Glycine, serine and threonine metabolism
ppeg00340  Histidine metabolism
ppeg00630  Glyoxylate and dicarboxylate metabolism
ppeg00730  Thiamine metabolism
ppeg00740  Riboflavin metabolism
ppeg00790  Folate biosynthesis
KO pathway
ko00230   

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