| Entry |
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| Name |
Glyoxylate and dicarboxylate metabolism |
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| Class |
Metabolism; Carbohydrate metabolism
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| Pathway map |
| rn00630 | Glyoxylate and dicarboxylate metabolism |
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| Module |
| M00741 | Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:rn00630] |
| M00968 | Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:rn00630] |
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| Other DBs |
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| Reaction |
| R00009 | hydrogen-peroxide:hydrogen-peroxide oxidoreductase |
| R00013 | glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming) |
| R00021 | L-glutamate:ferredoxin oxidoreductase (transaminating) |
| R00235 | acetate:CoA ligase (AMP-forming) |
| R00238 | acetyl-CoA:acetyl-CoA C-acetyltransferase |
| R00253 | L-glutamate:ammonia ligase (ADP-forming) |
| R00262 | L-threo-3-methylaspartate carboxy-aminomethylmutase |
| R00273 | oxalate:oxygen oxidoreductase |
| R00339 | (R,R)-tartrate hydro-lyase (oxaloacetate-forming) |
| R00342 | (S)-malate:NAD+ oxidoreductase |
| R00351 | acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing) |
| R00369 | L-alanine:glyoxylate aminotransferase |
| R00372 | glycine:2-oxoglutarate aminotransferase |
| R00373 | glycine:oxaloacetate aminotransferase |
| R00465 | glycolate:NADP+ oxidoreductase |
| R00466 | glyoxylate:oxygen oxidoreductase |
| R00468 | glyoxylate:NADP+ oxidoreductase (CoA-oxalylating) |
| R00470 | 4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming) |
| R00472 | acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming); L-malate glyoxylate-lyase (CoA-acetylating) |
| R00473 | L-malyl-CoA glyoxylate-lyase (acetyl-CoA-forming) |
| R00474 | 2-oxoglutarate:glyoxylate succinaldehydetransferase (decarboxylating); 2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating) |
| R00475 | glycolate:oxygen 2-oxidoreductase |
| R00476 | glycolate:acceptor 2-oxidoreductase |
| R00477 | 3-oxalomalate glyoxylate-lyase (oxaloacetate-forming) |
| R00479 | isocitrate glyoxylate-lyase (succinate-forming) |
| R00518 | ATP:formate phosphotransferase |
| R00519 | formate:NAD+ oxidoreductase |
| R00524 | formamide amidohydrolase |
| R00525 | N-formyl-L-glutamate amidohydrolase |
| R00526 | N-formyl-L-aspartate amidohydrolase |
| R00588 | L-serine:glyoxylate aminotransferase |
| R00653 | N-formyl-L-methionine amidohydrolase |
| R00717 | glycolate:NAD+ oxidoreductase |
| R00833 | (R)-methylmalonyl-CoA CoA-carbonylmutase |
| R00934 | L-erythro-3-methylmalyl-CoA glyoxylate-lyase (propanoyl-CoA-forming) |
| R00944 | 10-formyltetrahydrofolate amidohydrolase |
| R00945 | 5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase |
| R01180 | butanoyl-CoA:glyoxylate C-butanoyltransferase (thioester-hydrolysing, 1-carboxypropyl-forming); 3-ethylmalate glyoxylate-lyase (CoA-butanoylating) |
| R01221 | glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system |
| R01256 | (S)-malate:CoA ligase (ADP-forming) |
| R01325 | citrate hydro-lyase (cis-aconitate-forming) |
| R01333 | glycolaldehyde:NAD+ oxidoreductase |
| R01334 | 2-phosphoglycolate phosphohydrolase |
| R01388 | D-glycerate:NAD+ 2-oxidoreductase |
| R01392 | D-glycerate:NADP+ 2-oxidoreductase |
| R01393 | hydroxypyruvate carboxy-lyase (glycolaldehyde-forming) |
| R01394 | hydroxypyruvate aldose-ketose-isomerase |
| R01514 | ATP:(R)-glycerate 3-phosphotransferase |
| R01558 | oxalate:CoA ligase (AMP-forming) |
| R01559 | succinyl-CoA:oxalate CoA-transferase |
| R01745 | (R)-glycerate:NAD+ oxidoreductase |
| R01747 | (R)-glycerate:NADP+ oxidoreductase |
| R01749 | D-glycerate:NAD+ oxidoreductase (carboxylating) |
| R01750 | D-glycerate:NADP+ oxidoreductase (carboxylating) |
| R01781 | 1,2-ethanediol:NAD+ oxidoreductase |
| R01859 | propanoyl-CoA:carbon-dioxide ligase (ADP-forming) |
| R01900 | isocitrate hydro-lyase (cis-aconitate-forming) |
| R01908 | oxalyl-CoA carboxy-lyase (formyl-CoA-forming) |
| R01959 | N-formyl-L-kynurenine amidohydrolase |
| R01977 | (R)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase |
| R02509 | N,N-dimethylformamide amidohydrolase |
| R02544 | meso-tartrate:NAD+ oxidoreductase |
| R02545 | meso-tartaric acid:NAD+ oxidoreductase |
| R02546 | (R,R)-tartrate epimerase |
| R02547 | trans-2,3-epoxysuccinate hydrolase |
| R02765 | methylmalonyl-CoA epimerase |
| R03027 | (3R)-3-hydroxybutanoyl-CoA hydro-lyase |
| R03040 | 3-propylmalate glyoxylate-lyase (CoA-pentanoylating) |
| R03127 | dihydroxyfumarate carboxy-lyase |
| R03140 | D-ribulose 1,5-bisphosphate oxygenase |
| R03146 | formate:ferricytochrome-b1 oxidoreductase |
| R03696 | L-threo-3-methylaspartate ammonia-lyase |
| R05076 | (2R,3S)-2-methylmalyl-CoA hydro-lyase (2-methylfumaryl-CoA-forming) |
| R07290 | formyl-CoA:oxalate CoA-transferase |
| R07410 | L-aspartate:NAD+ oxidoreductase (deaminating) |
| R08572 | ATP:(R)-glycerate 2-phosphotransferase |
| R09291 | ethylmalonyl-CoA:NADP+ oxidoreductase (decarboxylating) |
| R09292 | (2R)-ethylmalonyl-CoA CoA-carbonylmutase |
| R09293 | (2S)-methylsuccinyl-CoA:electron-transfer flavoprotein oxidoreductase |
| R09718 | D-erythro-3-hydroxyaspartate glyoxylate-lyase (glycine-forming) |
| R09979 | (2S)-ethylmalonyl-CoA epimerase |
| R10612 | (S)-malyl-CoA hydrolase |
| R10904 | succinyl-CoA:mesaconate CoA-transferase |
| R12696 | D-ribulose 1-phosphate glycolaldehyde-lyase (glycerone-phosphate-forming) |
| R13090 | D-ribulose-1,5-bisphosphate 5-phosphohydrolase |
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| Compound |
| C01127 | 4-Hydroxy-2-oxoglutarate |
| C01146 | 2-Hydroxy-3-oxopropanoate |
| C01182 | D-Ribulose 1,5-bisphosphate |
| C03459 | 2-Hydroxy-3-oxosuccinate |
| C03548 | trans-2,3-Epoxysuccinate |
| C03561 | (R)-3-Hydroxybutanoyl-CoA |
| C03618 | L-threo-3-Methylaspartate |
| C06027 | L-erythro-3-Methylmalyl-CoA |
| C18324 | (2S)-Methylsuccinyl-CoA |
| C19838 | D-erythro-3-Hydroxyaspartate |
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| Reference |
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| Authors |
Njau RK, Herndon CA, Hawes JW. |
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| Title |
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae. |
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| Journal |
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| Reference |
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| Authors |
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G |
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| Title |
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria. |
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| Journal |
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| Reference |
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| Authors |
Erb TJ, Retey J, Fuchs G, Alber BE |
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| Title |
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases. |
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| Journal |
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| Reference |
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| Authors |
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM |
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| Title |
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation. |
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| Journal |
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| Reference |
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| Authors |
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A |
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| Title |
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco. |
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| Journal |
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| Reference |
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| Authors |
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA |
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| Title |
A methylaspartate cycle in haloarchaea. |
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| Journal |
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| Reference |
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| Authors |
Serrano JA, Bonete MJ |
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| Title |
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii. |
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| Journal |
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Related
pathway |
| rn00010 | Glycolysis / Gluconeogenesis |
| rn00053 | Ascorbate and aldarate metabolism |
| rn00250 | Alanine, aspartate and glutamate metabolism |
| rn00260 | Glycine, serine and threonine metabolism |
| rn00270 | Cysteine and methionine metabolism |
| rn00710 | Carbon fixation by Calvin cycle |
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| KO pathway |
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