KEGG   PATHWAY: scan00564
Entry
scan00564                   Pathway                                
Name
Glycerophospholipid metabolism - Serinus canaria (common canary)
Class
Metabolism; Lipid metabolism
Pathway map
scan00564  Glycerophospholipid metabolism
scan00564

Module
scan_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:scan00564]
scan_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:scan00564]
scan_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:scan00564]
Other DBs
GO: 0006650
Organism
Serinus canaria (common canary) [GN:scan]
Gene
103812286  LYPLA1; acyl-protein thioesterase 1 isoform X1 [KO:K06128] [EC:3.1.1.5]
103812467  LPCAT3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
103812852  DGKB; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
103812947  GPD1L; glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
103813604  PLA2G6; 85/88 kDa calcium-independent phospholipase A2 [KO:K16343] [EC:3.1.1.4]
103813786  PLPP4; phospholipid phosphatase 4 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
103813825  GPAM; glycerol-3-phosphate acyltransferase 1, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
103814010  SAMD8; sphingomyelin synthase-related protein 1 [KO:K22697] [EC:2.7.8.48 3.1.4.62]
103814032  CHAT; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
103814070  SGMS1; phosphatidylcholine:ceramide cholinephosphotransferase 1 [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
103814246  GPD2; glycerol-3-phosphate dehydrogenase, mitochondrial isoform X2 [KO:K00111] [EC:1.1.5.3]
103814303  [KO:K00006] [EC:1.1.1.8]
103814801  PLA2G4A; cytosolic phospholipase A2 isoform X1 [KO:K16342] [EC:3.1.1.4]
103815204  PLPP3; phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
103815294  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
103815374  PCYT1A; choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
103815457  DGKD; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
103815508  [KO:K00901] [EC:2.7.1.107]
103815759  AGPAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
103815926  PCYT1B; choline-phosphate cytidylyltransferase B [KO:K00968] [EC:2.7.7.15]
103816296  [KO:K00901] [EC:2.7.1.107]
103816468  PTDSS1; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
103816691  LCAT; phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
103816810  LPCAT2; LOW QUALITY PROTEIN: lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
103816813  PLA2G15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
103817373  AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X2 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
103817601  PEMT; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
103817906  PLA2G10; group 10 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
103818023  PISD; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
103818042  PLA2G1B; phospholipase A2 isoform X2 [KO:K01047] [EC:3.1.1.4]
103818205  PLA2G3; group 3 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
103818552  GNPAT; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
103818791  LPIN3; phosphatidate phosphatase LPIN3 isoform X1 [KO:K15728] [EC:3.1.3.4]
103818954  AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta [KO:K13509] [EC:2.3.1.51]
103819174  PNPLA7; patatin-like phospholipase domain-containing protein 7 isoform X1 [KO:K14676] [EC:3.1.1.5]
103819430  MBOAT1; lysophospholipid acyltransferase 1 isoform X2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
103819619  DGKI; diacylglycerol kinase iota isoform X2 [KO:K00901] [EC:2.7.1.107]
103819647  CHPT1; cholinephosphotransferase 1 isoform X1 [KO:K00994] [EC:2.7.8.2]
103819731  PCYT2; ethanolamine-phosphate cytidylyltransferase isoform X1 [KO:K00967] [EC:2.7.7.14]
103819799  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
103819926  PGS1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
103820037  [KO:K13509] [EC:2.3.1.51]
103820129  AGPAT5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
103820293  PROCA1; protein PROCA1 [KO:K01047] [EC:3.1.1.4]
103820502  ETNK1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
103820625  LPIN1; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
103821097  PLPP1; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
103821257  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
103821321  LCLAT1; lysocardiolipin acyltransferase 1 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
103821340  GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X2 [KO:K18695] [EC:3.1.4.2]
103821386  CRLS1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
103821523  LPGAT1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform X2 [KO:K13514] [EC:2.3.1.-]
103821540  PLB1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
103821673  [KO:K13509] [EC:2.3.1.51]
103821938  PLPP2; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
103822374  CEPT1; choline/ethanolaminephosphotransferase 1 isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
103822684  GPAT4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
103822696  PLPP5; phospholipid phosphatase 5 isoform X2 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
103822730  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
103822898  MBOAT2; lysophospholipid acyltransferase 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
103823561  LYPLA2; acyl-protein thioesterase 2 isoform X1 [KO:K06130] [EC:3.1.1.5]
103823709  PLA2G12B; group XIIB secretory phospholipase A2-like protein [KO:K01047] [EC:3.1.1.4]
103823858  GPD1; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic isoform X1 [KO:K00006] [EC:1.1.1.8]
103823912  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
103824087  CHKA; choline kinase alpha isoform X3 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
103824340  [KO:K01047] [EC:3.1.1.4]
103824355  [KO:K01047] [EC:3.1.1.4]
103824356  [KO:K01047] [EC:3.1.1.4]
103824509  ETNK2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
103824560  SELENOI; ethanolaminephosphotransferase 1 isoform X1 [KO:K00993] [EC:2.7.8.1]
103824958  PNPLA6; LOW QUALITY PROTEIN: neuropathy target esterase [KO:K14676] [EC:3.1.1.5]
103825423  PHOSPHO1; phosphoethanolamine/phosphocholine phosphatase [KO:K06124] [EC:3.1.3.75]
103825973  LPCAT1; lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
103826002  PLA2G12A; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
103826006  ETNPPL; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
103826010  SGMS2; phosphatidylcholine:ceramide cholinephosphotransferase 2 [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
103826083  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
103826085  [KO:K13506] [EC:2.3.1.15]
103826086  [KO:K13506] [EC:2.3.1.15]
103826384  PLD4; phospholipase D4 [KO:K16860] [EC:3.1.4.4]
103826646  PLA2G4F; cytosolic phospholipase A2 zeta isoform X1 [KO:K16342] [EC:3.1.1.4]
103826647  [KO:K16342] [EC:3.1.1.4]
103826648  [KO:K16342] [EC:3.1.1.4]
103826650  [KO:K16342] [EC:3.1.1.4]
103826812  PTDSS2; phosphatidylserine synthase 2 isoform X2 [KO:K08730] [EC:2.7.8.29]
103826873  LPIN2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
103826977  [KO:K16342] [EC:3.1.1.4]
103826978  [KO:K16342] [EC:3.1.1.4]
103826979  [KO:K16342] [EC:3.1.1.4]
103826981  [KO:K16342] [EC:3.1.1.4]
103826983  [KO:K16342] [EC:3.1.1.4]
103826994  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
103827085  [KO:K01047] [EC:3.1.1.4]
103827111  PLA1A; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
103827344  [KO:K00993] [EC:2.7.8.1]
103827432  DGKH; diacylglycerol kinase eta isoform X4 [KO:K00901] [EC:2.7.1.107]
108963187  [KO:K00629] [EC:2.3.1.15]
115484461  [KO:K01047] [EC:3.1.1.4]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
scan00010  Glycolysis / Gluconeogenesis
scan00260  Glycine, serine and threonine metabolism
scan00561  Glycerolipid metabolism
scan00562  Inositol phosphate metabolism
scan00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
scan00565  Ether lipid metabolism
scan00620  Pyruvate metabolism
KO pathway
ko00564   

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