KEGG   PATHWAY: seb00630
Entry
seb00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Salmonella enterica subsp. enterica serovar Typhimurium ST4/74
Class
Metabolism; Carbohydrate metabolism
Pathway map
seb00630  Glyoxylate and dicarboxylate metabolism
seb00630

Module
seb_M00012  Glyoxylate cycle [PATH:seb00630]
seb_M00621  Glycine cleavage system [PATH:seb00630]
Other DBs
GO: 0046487 0043648
Organism
Salmonella enterica subsp. enterica serovar Typhimurium ST4/74 [GN:seb]
Gene
STM474_0162  lpdA; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
STM474_0167  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
STM474_0384  prpC; methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
STM474_0538  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
STM474_0539  gip; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
STM474_0540  glxR; tartronic semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
STM474_0546  glxK; glycerate kinase II [KO:K00865] [EC:2.7.1.165]
STM474_0753  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
STM474_1130  ycdW; putative oxidoreductase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
STM474_1323  katE; hydroperoxidase II [KO:K03781] [EC:1.11.1.6]
STM474_1727  acnA; aconitate hydratase [KO:K27802]
STM474_1773  purU; formyltetrahydrofolate hydrolase [KO:K01433] [EC:3.5.1.10]
STM474_1916  eda; keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
STM474_2659  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
STM474_3104  [KO:K00865] [EC:2.7.1.165]
STM474_3118  fucO; L-1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
STM474_3166  yqeF; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
STM474_3200  gcvP; glycine cleavage complex protein P, glycine decarboxylase [KO:K00281] [EC:1.4.4.2]
STM474_3201  gcvH; glycine cleavage system protein H [KO:K02437]
STM474_3202  gcvT; glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
STM474_3404  garK; glycerate kinase I [KO:K00865] [EC:2.7.1.165]
STM474_3405  garR; tartronate semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
STM474_3514  [KO:K03780] [EC:4.2.1.32]
STM474_3515  [KO:K03779] [EC:4.2.1.32]
STM474_3519  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
STM474_3649  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
STM474_3818  yiaE; 2-hydroxyacid dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
STM474_4185  [KO:K01915] [EC:6.3.1.2]
STM474_4214  fdoI; formate dehydrogenase-O subunit gamma [KO:K00127]
STM474_4215  fdoH; formate dehydrogenase-O beta subunit [KO:K00124]
STM474_4216  fdoG; formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
STM474_4372  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
STM474_4373  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
STM474_4471  acs; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00049  L-Aspartate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C05840  Iminoaspartate
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C19838  D-erythro-3-Hydroxyaspartate
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
seb00010  Glycolysis / Gluconeogenesis
seb00020  Citrate cycle (TCA cycle)
seb00030  Pentose phosphate pathway
seb00053  Ascorbate and aldarate metabolism
seb00071  Fatty acid degradation
seb00230  Purine metabolism
seb00250  Alanine, aspartate and glutamate metabolism
seb00260  Glycine, serine and threonine metabolism
seb00270  Cysteine and methionine metabolism
seb00620  Pyruvate metabolism
seb00710  Carbon fixation by Calvin cycle
seb00750  Vitamin B6 metabolism
seb00910  Nitrogen metabolism
KO pathway
ko00630   

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