KEGG   PATHWAY: sho00230
Entry
sho00230                    Pathway                                
Name
Purine metabolism - Streptomyces hygroscopicus subsp. jinggangensis TL01
Class
Metabolism; Nucleotide metabolism
Pathway map
sho00230  Purine metabolism
sho00230

Module
sho_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sho00230]
sho_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sho00230]
sho_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sho00230]
sho_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sho00230]
sho_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sho00230]
sho_M00546  Purine degradation, xanthine => urea [PATH:sho00230]
sho_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:sho00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces hygroscopicus subsp. jinggangensis TL01 [GN:sho]
Gene
SHJGH_4760  hypothetical protein [KO:K13988] [EC:3.6.1.13]
SHJGH_7046  NTP pyrophosphohydrolase including oxidative damage repair enzyme [KO:K01515] [EC:3.6.1.13 3.6.1.-]
SHJGH_1760  putative phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
SHJGH_4357  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
SHJGH_4774  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
SHJGH_4788  phosphoribosylglycinamide synthetase [KO:K01945] [EC:6.3.4.13]
SHJGH_5677  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
SHJGH_4779  phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
SHJGH_4781  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
SHJGH_4780  phosphoribosylformylglycinamidine synthase subunit I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
SHJGH_4773  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
SHJGH_4287  phosphoribosylaminoimidazole carboxylase ATPase subunit PurK [KO:K01589] [EC:6.3.4.18]
SHJGH_4286  phosphoribosylaminoimidazole carboxylase catalytic subunit PurE [KO:K01588] [EC:5.4.99.18]
SHJGH_4784  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
SHJGH_2456  putative adenylosuccino lyase [KO:K01756] [EC:4.3.2.2]
SHJGH_5678  bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
SHJGH_2702  adenine phosphoribosyltransferase (APRT) [KO:K00759] [EC:2.4.2.7]
SHJGH_4694  secreted 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
SHJGH_4100  N-acetylglucosamine-6-phosphate deacetylase [KO:K02566] [EC:3.1.3.5]
SHJGH_5793  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
SHJGH_3326  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
SHJGH_5295  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
SHJGH_5629  inosine 5' monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
SHJGH_5630  inositol-5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
SHJGH_3869  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
SHJGH_4130  hypothetical protein [KO:K01519] [EC:3.6.1.66]
SHJGH_0508  oxidoreductase [KO:K11177] [EC:1.17.1.4]
SHJGH_7535  oxidoreductase [KO:K11177] [EC:1.17.1.4]
SHJGH_0509  oxidoreductase molybdopterin binding subunit [KO:K11178] [EC:1.17.1.4]
SHJGH_7534  putative oxidoreductase, molybdopterin binding subunit [KO:K11178] [EC:1.17.1.4]
SHJGH_0510  oxidoreductase, iron-sulfur binding subunit [KO:K13483]
SHJGH_7533  putative oxidoreductase, iron-sulfur binding subunit [KO:K13483]
SHJGH_5644  bifunctional GMP synthase/glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
SHJGH_2656  inositol-5-monophosphate dehydrogenase [KO:K26110] [EC:1.7.1.7]
SHJGH_2668  guanylate kinase [KO:K00942] [EC:2.7.4.8]
SHJGH_p1071  putative guanylate kinase [KO:K00942] [EC:2.7.4.8]
SHJGH_3545  ribonucleoside-diphosphate reductase alpha chain [KO:K00525] [EC:1.17.4.1]
SHJGH_6102  ribonucleoside-diphosphate reductase alpha chain [KO:K00525] [EC:1.17.4.1]
SHJGH_6663  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
SHJGH_3546  ribonucleoside-diphosphate reductase beta chain [KO:K00526] [EC:1.17.4.1]
SHJGH_6101  ribonucleoside-diphosphate reductase beta chain [KO:K00526] [EC:1.17.4.1]
SHJGH_3711  deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
SHJGH_2700  (p)ppGpp synthetase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
SHJGH_6652  ppGpp synthetase/hydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
SHJGH_5343  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SHJGH_4324  hydrolase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SHJGH_8002  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SHJGH_5804  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
SHJGH_5161  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
SHJGH_3403  carbohydrate kinase [KO:K00856] [EC:2.7.1.20]
SHJGH_1757  putative adenosine deaminase [KO:K01488] [EC:3.5.4.4]
SHJGH_5534  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
SHJGH_5777  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
SHJGH_1934  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
SHJGH_3800  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
SHJGH_3254  2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
SHJGH_2201  adenylate kinase [KO:K00939] [EC:2.7.4.3]
SHJGH_5580  adenylate kinase [KO:K00939] [EC:2.7.4.3]
SHJGH_2139  putative secreted phosphohydrolase [KO:K03651] [EC:3.1.4.53]
SHJGH_2718  HIT family protein [KO:K19710] [EC:2.7.7.53]
SHJGH_6946  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
SHJGH_6944  sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
SHJGH_6945  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
SHJGH_7031  uricase [KO:K00365] [EC:1.7.3.3]
SHJGH_7030  hypothetical protein [KO:K07127] [EC:3.5.2.17]
SHJGH_7029  hypothetical protein [KO:K16840] [EC:4.1.1.97]
SHJGH_5743  hypothetical protein [KO:K16840] [EC:4.1.1.97]
SHJGH_3220  putative hydantoin racemase [KO:K16841] [EC:5.1.99.3]
SHJGH_7056  allantoinase [KO:K01466] [EC:3.5.2.5]
SHJGH_7057  allantoicase [KO:K01477] [EC:3.5.3.4]
SHJGH_2432  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
SHJGH_6387  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
SHJGH_2433  urease subunit beta [KO:K01429] [EC:3.5.1.5]
SHJGH_2434  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
SHJGH_6386  fusion of urease beta and gamma subunits [KO:K14048] [EC:3.5.1.5]
SHJGH_1327  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sho00030  Pentose phosphate pathway
sho00220  Arginine biosynthesis
sho00250  Alanine, aspartate and glutamate metabolism
sho00260  Glycine, serine and threonine metabolism
sho00340  Histidine metabolism
sho00630  Glyoxylate and dicarboxylate metabolism
sho00730  Thiamine metabolism
sho00740  Riboflavin metabolism
sho00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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