KEGG   PATHWAY: spad00630
Entry
spad00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces paludis
Class
Metabolism; Carbohydrate metabolism
Pathway map
spad00630  Glyoxylate and dicarboxylate metabolism
spad00630

Module
spad_M00621  Glycine cleavage system [PATH:spad00630]
spad_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:spad00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces paludis [GN:spad]
Gene
DVK44_32190  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
DVK44_13970  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DVK44_29165  malate synthase A [KO:K01638] [EC:2.3.3.9]
DVK44_21545  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DVK44_09870  citrate synthase [KO:K01647] [EC:2.3.3.1]
DVK44_19760  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
DVK44_26820  helix-turn-helix domain-containing protein [KO:K01647] [EC:2.3.3.1]
DVK44_26825  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
DVK44_28315  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
DVK44_30710  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DVK44_21245  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DVK44_24655  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DVK44_24650  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
DVK44_29745  protein meaA [KO:K14447] [EC:5.4.99.63]
DVK44_22315  biotin/lipoyl-binding protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
DVK44_22350  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
DVK44_22345  acyl-CoA carboxylase subunit epsilon [KO:K27095]
DVK44_02350  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
DVK44_02355  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
DVK44_07690  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
DVK44_10620  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
DVK44_22945  catalase [KO:K03781] [EC:1.11.1.6]
DVK44_33705  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DVK44_19455  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
DVK44_27810  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
DVK44_03955  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DVK44_06920  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
DVK44_06990  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DVK44_07105  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DVK44_00570  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DVK44_10270  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DVK44_24490  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DVK44_25285  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DVK44_02835  gcvP; glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
DVK44_25295  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
DVK44_33135  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DVK44_06845  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DVK44_25290  gcvH; glycine cleavage system protein GcvH [KO:K02437]
DVK44_29715  glycerate kinase [KO:K00865] [EC:2.7.1.165]
DVK44_24120  glycerate kinase [KO:K00865] [EC:2.7.1.165]
DVK44_07570  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
DVK44_31630  2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
DVK44_24070  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
DVK44_00500  cyclase family protein [KO:K07130] [EC:3.5.1.9]
DVK44_19875  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
spad00010  Glycolysis / Gluconeogenesis
spad00020  Citrate cycle (TCA cycle)
spad00030  Pentose phosphate pathway
spad00053  Ascorbate and aldarate metabolism
spad00071  Fatty acid degradation
spad00230  Purine metabolism
spad00250  Alanine, aspartate and glutamate metabolism
spad00260  Glycine, serine and threonine metabolism
spad00620  Pyruvate metabolism
spad00710  Carbon fixation by Calvin cycle
spad00750  Vitamin B6 metabolism
spad00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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