KEGG   PATHWAY: spad00230
Entry
spad00230                   Pathway                                
Name
Purine metabolism - Streptomyces paludis
Class
Metabolism; Nucleotide metabolism
Pathway map
spad00230  Purine metabolism
spad00230

Module
spad_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:spad00230]
spad_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:spad00230]
spad_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:spad00230]
spad_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:spad00230]
spad_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:spad00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces paludis [GN:spad]
Gene
DVK44_31425  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
DVK44_20880  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
DVK44_14750  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
DVK44_17125  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
DVK44_21515  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
DVK44_17195  phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
DVK44_17185  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
DVK44_17190  phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
DVK44_14745  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
DVK44_11315  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
DVK44_11310  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
DVK44_17140  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
DVK44_27695  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
DVK44_02155  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
DVK44_21520  bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
DVK44_03400  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
DVK44_14365  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
DVK44_21955  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
DVK44_10300  HAD family hydrolase [KO:K02566] [EC:3.1.3.5]
DVK44_22290  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
DVK44_06355  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
DVK44_13375  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
DVK44_21330  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
DVK44_21335  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
DVK44_09150  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
DVK44_10470  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
DVK44_21390  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
DVK44_03180  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
DVK44_03230  guanylate kinase [KO:K00942] [EC:2.7.4.8]
DVK44_23750  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
DVK44_26700  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
DVK44_23745  ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
DVK44_08410  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
DVK44_03395  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
DVK44_26645  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
DVK44_13105  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
DVK44_21180  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
DVK44_22360  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
DVK44_23705  CYTH domain-containing protein [KO:K05873] [EC:4.6.1.1]
DVK44_18395  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
DVK44_06700  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
DVK44_12175  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
DVK44_22175  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
DVK44_05960  bifunctional metallophosphatase/5'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
DVK44_11875  adenylate kinase [KO:K00939] [EC:2.7.4.3]
DVK44_03475  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
DVK44_28710  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
DVK44_28700  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
DVK44_28705  sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
DVK44_29130  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
DVK44_29125  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
DVK44_21810  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
DVK44_29185  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
DVK44_29190  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
DVK44_02010  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
DVK44_02015  urease subunit beta [KO:K01429] [EC:3.5.1.5]
DVK44_02020  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
DVK44_00495  tyramine oxidase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
spad00030  Pentose phosphate pathway
spad00220  Arginine biosynthesis
spad00250  Alanine, aspartate and glutamate metabolism
spad00260  Glycine, serine and threonine metabolism
spad00340  Histidine metabolism
spad00630  Glyoxylate and dicarboxylate metabolism
spad00730  Thiamine metabolism
spad00740  Riboflavin metabolism
spad00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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