KEGG   PATHWAY: sply00230
Entry
sply00230                   Pathway                                
Name
Purine metabolism - Serratia inhibens
Class
Metabolism; Nucleotide metabolism
Pathway map
sply00230  Purine metabolism
sply00230

Module
sply_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sply00230]
sply_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sply00230]
sply_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sply00230]
sply_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sply00230]
sply_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sply00230]
sply_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:sply00230]
sply_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:sply00230]
Other DBs
GO: 0006163 0042278
Organism
Serratia inhibens [GN:sply]
Gene
Q5A_022275  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Q5A_024010  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
Q5A_002825  deoB; Phosphopentomutase [KO:K01839] [EC:5.4.2.7]
Q5A_006230  pgm; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
Q5A_009965  prs; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Q5A_017610  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Q5A_001395  purD_1; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Q5A_018730  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Q5A_014695  purT; Phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
Q5A_019285  purL; Phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
Q5A_018725  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Q5A_005405  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
Q5A_005410  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
Q5A_018625  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Q5A_010135  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Q5A_001400  purH; Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Q5A_005270  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Q5A_005320  mggB; Mannosylglucosyl-3-phosphoglycerate phosphatase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
Q5A_003630  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Q5A_006140  nagD; Ribonucleotide monophosphatase NagD [KO:K02566] [EC:3.1.3.5]
Q5A_024020  yrfG; GMP/IMP nucleotidase YrfG [KO:K20881] [EC:3.1.3.-]
Q5A_005305  gsk; Inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
Q5A_022185  xapA; Purine nucleoside phosphorylase 2 [KO:K03783] [EC:2.4.2.1]
Q5A_002830  deoD; Purine nucleoside phosphorylase DeoD-type [KO:K03784] [EC:2.4.2.1]
Q5A_004665  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
Q5A_003925  yfiH_1; Laccase domain protein YfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Q5A_022895  rihB; Pyrimidine-specific ribonucleoside hydrolase RihB [KO:K25589] [EC:3.2.2.2 3.2.2.3]
Q5A_021180  hpt; Hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Q5A_019025  guaB; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Q5A_019110  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Q5A_002900  yjjX; Non-canonical purine NTP phosphatase [KO:K01529] [EC:3.6.1.73]
Q5A_021330  rdgB; dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
Q5A_004360  gpt; Xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
Q5A_011800  hcrC; 4-hydroxybenzoyl-CoA reductase subunit gamma [KO:K13481] [EC:1.17.1.4]
Q5A_011805  xdhA; Xanthine dehydrogenase molybdenum-binding subunit [KO:K13482] [EC:1.17.1.4]
Q5A_013490  guaA_1; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
Q5A_019020  guaA_2; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
Q5A_022495  ipuF; Gamma-glutamyl-L-1-hydroxyisopropylamide hydrolase [KO:K01951] [EC:6.3.5.2]
Q5A_003370  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
Q5A_011795  guaD; Guanine deaminase [KO:K01487] [EC:3.5.4.3]
Q5A_025225  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
Q5A_019655  nrdE; Ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
Q5A_017295  nrdA; Ribonucleoside-diphosphate reductase 1 subunit alpha [KO:K00525] [EC:1.17.4.1]
Q5A_019660  nrdF; Ribonucleoside-diphosphate reductase 2 subunit beta [KO:K00526] [EC:1.17.4.1]
Q5A_017300  nrdB; Ribonucleoside-diphosphate reductase 1 subunit beta [KO:K00526] [EC:1.17.4.1]
Q5A_002235  nrdD; Anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
Q5A_003430  dgt; Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Q5A_017520  yfbR_1; 5'-deoxynucleotidase YfbR [KO:K08722] [EC:3.1.3.89]
Q5A_025235  spoT; Bifunctional (p)ppGpp synthase/hydrolase SpoT [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Q5A_000660  gppA; Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Q5A_018770  ppx; Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Q5A_003490  relA_2; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
Q5A_000785  cyaA; Adenylate cyclase [KO:K05851] [EC:4.6.1.1]
Q5A_006295  hypothetical protein [KO:K01120] [EC:3.1.4.17]
Q5A_001735  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Q5A_011565  add2; Aminodeoxyfutalosine deaminase [KO:K01488] [EC:3.5.4.4]
Q5A_016350  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
Q5A_020055  ygdH; LOG family protein YgdH [KO:K06966] [EC:3.2.2.10 3.2.2.-]
Q5A_001820  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
Q5A_006385  yfkN; Trifunctional nucleotide phosphoesterase protein YfkN [KO:K01119] [EC:3.1.4.16 3.1.3.6]
Q5A_005295  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
Q5A_003495  mazG; Nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
Q5A_022265  cpdA; 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
Q5A_003105  apaH; Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [KO:K01525] [EC:3.6.1.41]
Q5A_003600  cysC; Adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
Q5A_003595  cysN; Sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
Q5A_003590  cysD; Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
Q5A_011910  hpxO; FAD-dependent urate hydroxylase [KO:K16839] [EC:1.14.13.113]
Q5A_004220  hiuH; 5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
Q5A_004215  hypothetical protein [KO:K16840] [EC:4.1.1.97]
Q5A_004110  hypothetical protein [KO:K16841] [EC:5.1.99.3]
Q5A_004115  pgdA; Peptidoglycan deacetylase [KO:K16842] [EC:3.5.2.5]
Q5A_004210  hyuC; Hydantoin utilization protein C [KO:K02083] [EC:3.5.3.9]
Q5A_004205  pucG; Purine catabolism protein PucG [KO:K00839] [EC:2.6.1.112]
Q5A_004165  atzE; Biuret hydrolase [KO:K22601] [EC:2.1.3.5]
Q5A_004175  ywrD; Putative gamma-glutamyltransferase YwrD [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sply00030  Pentose phosphate pathway
sply00220  Arginine biosynthesis
sply00250  Alanine, aspartate and glutamate metabolism
sply00260  Glycine, serine and threonine metabolism
sply00340  Histidine metabolism
sply00630  Glyoxylate and dicarboxylate metabolism
sply00730  Thiamine metabolism
sply00740  Riboflavin metabolism
sply00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

DBGET integrated database retrieval system