KEGG   PATHWAY: spu00630
Entry
spu00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Strongylocentrotus purpuratus (purple sea urchin)
Class
Metabolism; Carbohydrate metabolism
Pathway map
spu00630  Glyoxylate and dicarboxylate metabolism
spu00630

Module
spu_M00621  Glycine cleavage system [PATH:spu00630]
spu_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:spu00630]
Other DBs
GO: 0046487 0043648
Organism
Strongylocentrotus purpuratus (purple sea urchin) [GN:spu]
Gene
585742  acetyl-coenzyme A synthetase 2-like, mitochondrial [KO:K01895] [EC:6.2.1.1]
592086  acetyl-coenzyme A synthetase, cytoplasmic [KO:K01895] [EC:6.2.1.1]
115918532  acetyl-coenzyme A synthetase, cytoplasmic-like [KO:K01895] [EC:6.2.1.1]
591635  malate dehydrogenase, cytoplasmic [KO:K00025] [EC:1.1.1.37]
587163  malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
115926793  malate dehydrogenase, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
590444  citrate synthase, mitochondrial [KO:K01647] [EC:2.3.3.1]
577783  aconitate hydratase, mitochondrial isoform X1 [KO:K01681] [EC:4.2.1.3]
586198  cytoplasmic aconitate hydratase isoform X1 [KO:K01681] [EC:4.2.1.3]
763037  acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
584928  acetyl-CoA acetyltransferase, mitochondrial [KO:K00626] [EC:2.3.1.9]
115927929  acetyl-CoA acetyltransferase, cytosolic-like [KO:K00626] [EC:2.3.1.9]
579089  acetyl-CoA acetyltransferase, cytosolic-like [KO:K00626] [EC:2.3.1.9]
115928354  acetyl-CoA acetyltransferase, cytosolic-like [KO:K00626] [EC:2.3.1.9]
576505  methylmalonyl-CoA epimerase, mitochondrial [KO:K05606] [EC:5.1.99.1]
582365  propionyl-CoA carboxylase alpha chain, mitochondrial isoform X1 [KO:K01965] [EC:6.4.1.3]
592281  propionyl-CoA carboxylase beta chain, mitochondrial [KO:K01966] [EC:6.4.1.3 2.1.3.15]
576452  methylmalonyl-CoA mutase, mitochondrial isoform X1 [KO:K01847] [EC:5.4.99.2]
594782  hydroxyacid oxidase 1 [KO:K11517] [EC:1.1.3.15]
585244  hydroxyacid oxidase 1 [KO:K11517] [EC:1.1.3.15]
586372  hydroxyacid oxidase 1 [KO:K11517] [EC:1.1.3.15]
115923842  peroxisomal (S)-2-hydroxy-acid oxidase GLO5-like [KO:K11517] [EC:1.1.3.15]
115923843  hydroxyacid oxidase 1-like [KO:K11517] [EC:1.1.3.15]
105439393  hydroxyacid oxidase 1-like [KO:K11517] [EC:1.1.3.15]
115924135  hydroxyacid oxidase 1-like [KO:K11517] [EC:1.1.3.15]
100890229  hydroxyacid oxidase 1 [KO:K11517] [EC:1.1.3.15]
584548  hydroxyacid oxidase 1-like [KO:K11517] [EC:1.1.3.15]
590153  hydroxyacid oxidase 1 [KO:K11517] [EC:1.1.3.15]
578272  hydroxyacid oxidase 2 [KO:K11517] [EC:1.1.3.15]
575110  hydroxyacid oxidase 1 isoform X1 [KO:K11517] [EC:1.1.3.15]
583653  LOW QUALITY PROTEIN: hydroxyacid oxidase 1 [KO:K11517] [EC:1.1.3.15]
105438524  hydroxyacid oxidase 2-like [KO:K11517] [EC:1.1.3.15]
752067  hydroxyacid oxidase 1 [KO:K11517] [EC:1.1.3.15]
115926388  hydroxyacid oxidase 1-like [KO:K11517] [EC:1.1.3.15]
115926389  hydroxyacid oxidase 1-like [KO:K11517] [EC:1.1.3.15]
115918826  hydroxyacid oxidase 1-like [KO:K11517] [EC:1.1.3.15]
592375  LOW QUALITY PROTEIN: hydroxyacid oxidase 1 [KO:K11517] [EC:1.1.3.15]
105446915  hydroxyacid oxidase 1-like [KO:K11517] [EC:1.1.3.15]
584105  hydroxyacid oxidase 1 [KO:K11517] [EC:1.1.3.15]
589061  hydroxyacid oxidase 1-like [KO:K11517] [EC:1.1.3.15]
591284  hydroxyacid oxidase 1-like [KO:K11517] [EC:1.1.3.15]
590358  hydroxyacid oxidase 1 [KO:K11517] [EC:1.1.3.15]
548621  catalase [KO:K03781] [EC:1.11.1.6]
100888042  catalase-like [KO:K03781] [EC:1.11.1.6]
588349  glyoxylate reductase/hydroxypyruvate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
115921758  glyoxylate reductase/hydroxypyruvate reductase-like [KO:K00049] [EC:1.1.1.79 1.1.1.81]
105438914  glyoxylate reductase/hydroxypyruvate reductase-like [KO:K00049] [EC:1.1.1.79 1.1.1.81]
589691  glycerol-3-phosphate phosphatase [KO:K19269] [EC:3.1.3.18 3.1.3.48]
575497  serine--pyruvate aminotransferase, mitochondrial [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
574926  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
593509  serine hydroxymethyltransferase, cytosolic isoform X2 [KO:K00600] [EC:2.1.2.1]
754129  serine hydroxymethyltransferase, mitochondrial [KO:K00600] [EC:2.1.2.1]
578453  glycine dehydrogenase (decarboxylating), mitochondrial isoform X1 [KO:K00281] [EC:1.4.4.2]
579900  aminomethyltransferase, mitochondrial [KO:K00605] [EC:2.1.2.10]
577103  dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
576609  uncharacterized protein LOC576609 [KO:K02437]
100893526  putative hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
585085  glycerate kinase [KO:K11529] [EC:2.7.1.165]
579934  4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
100893038  kynurenine formamidase [KO:K01432] [EC:3.5.1.9]
115929317  kynurenine formamidase-like [KO:K01432] [EC:3.5.1.9]
752252  kynurenine formamidase-like [KO:K01432] [EC:3.5.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
spu00010  Glycolysis / Gluconeogenesis
spu00020  Citrate cycle (TCA cycle)
spu00030  Pentose phosphate pathway
spu00053  Ascorbate and aldarate metabolism
spu00071  Fatty acid degradation
spu00230  Purine metabolism
spu00250  Alanine, aspartate and glutamate metabolism
spu00260  Glycine, serine and threonine metabolism
spu00620  Pyruvate metabolism
spu00750  Vitamin B6 metabolism
spu00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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