KEGG   PATHWAY: stm00230
Entry
stm00230                    Pathway                                
Name
Purine metabolism - Salmonella enterica subsp. enterica serovar Typhimurium LT2
Class
Metabolism; Nucleotide metabolism
Pathway map
stm00230  Purine metabolism
stm00230

Module
stm_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:stm00230]
stm_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:stm00230]
stm_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:stm00230]
stm_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:stm00230]
stm_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:stm00230]
Other DBs
GO: 0006163 0042278
Organism
Salmonella enterica subsp. enterica serovar Typhimurium LT2 [GN:stm]
Gene
STM3185  yqiE; ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
STM3494  yrfE; putative NTP pyrophosphohydrolase [KO:K08312] [EC:3.6.1.-]
STM4569  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
STM0698  pgm; phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
STM1780  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
STM2362  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
STM4175  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
STM2500  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
STM1883  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
STM2565  purG; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
STM2499  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
STM0533  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
STM0534  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
STM2487  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
STM1232  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
STM4176  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
STM0483  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
STM0494  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
STM2927  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
STM0681  nagD; UMP phosphatase [KO:K02566] [EC:3.1.3.5]
STM3496  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
STM0491  gsk; inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
STM2422  xapA; purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
STM4570  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
STM0391  yaiE; hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
STM2661  yfiH; hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
STM0170  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
STM2511  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
STM2526  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
STM4584  yjjX; inosine/xanthosine triphosphatase [KO:K01529] [EC:3.6.1.73]
STM3103  yggV; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
STM0317  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
STM2510  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
STM2437  yfeJ; putative GMP synthase [KO:K01951] [EC:6.3.5.2]
STM0141  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
STM3740  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
STM2277  nrdA; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
STM2807  nrdE; ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
STM2278  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
STM2808  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
STM4452  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
STM0208  dgt; dGTPase [KO:K01129] [EC:3.1.5.1]
STM2332  5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
STM3742  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
STM3913  gppA; guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
STM2502  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
STM2956  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
STM3939  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
STM4366  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
STM1463  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
STM2009  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
STM2969  ygdH; LOG family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
STM4403  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
STM0488  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
STM2954  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
STM3183  icc; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
STM0088  apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [KO:K01525] [EC:3.6.1.41]
STM2933  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
STM2934  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
STM2935  cysD; sulfate adenylyltransferase small subunit [KO:K00957] [EC:2.7.7.4]
STM1097  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
STM0523  allB; allantoinase [KO:K01466] [EC:3.5.2.5]
STM0527  allC; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
STM0526  ylbA; (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
STM0515  allA; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
STM0528  allD; ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
STM0532  arcC; putative carbamate kinase [KO:K00926] [EC:2.7.2.2]
STM4466  putative carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
stm00030  Pentose phosphate pathway
stm00220  Arginine biosynthesis
stm00250  Alanine, aspartate and glutamate metabolism
stm00260  Glycine, serine and threonine metabolism
stm00340  Histidine metabolism
stm00630  Glyoxylate and dicarboxylate metabolism
stm00730  Thiamine metabolism
stm00740  Riboflavin metabolism
stm00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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