KEGG   PATHWAY: sxn00230
Entry
sxn00230                    Pathway                                
Name
Purine metabolism - Streptomyces xanthii
Class
Metabolism; Nucleotide metabolism
Pathway map
sxn00230  Purine metabolism
sxn00230

Module
sxn_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sxn00230]
sxn_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sxn00230]
sxn_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sxn00230]
sxn_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sxn00230]
sxn_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sxn00230]
sxn_M00546  Purine degradation, xanthine => urea [PATH:sxn00230]
sxn_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:sxn00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces xanthii [GN:sxn]
Gene
IAG42_01900  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
IAG42_20685  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
IAG42_16935  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
IAG42_17035  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
IAG42_13670  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
IAG42_16965  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
IAG42_16975  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
IAG42_16970  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
IAG42_16930  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
IAG42_21095  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
IAG42_21100  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
IAG42_17020  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
IAG42_30695  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
IAG42_13665  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
IAG42_29565  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
IAG42_16440  5'-nucleotidase C-terminal domain-containing protein [KO:K01081] [EC:3.1.3.5]
IAG42_36115  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
IAG42_22205  HAD family hydrolase [KO:K02566] [EC:3.1.3.5]
IAG42_13110  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
IAG42_26230  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
IAG42_19580  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
IAG42_13925  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
IAG42_13930  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
IAG42_23625  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
IAG42_21885  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
IAG42_07235  FAD binding domain-containing protein [KO:K13481] [EC:1.17.1.4]
IAG42_07230  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
IAG42_31310  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
IAG42_31305  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
IAG42_31300  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
IAG42_13845  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
IAG42_29790  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
IAG42_29730  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
IAG42_08690  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
IAG42_11615  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
IAG42_11620  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
IAG42_24265  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
IAG42_29570  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
IAG42_08750  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
IAG42_19860  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
IAG42_20890  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
IAG42_13055  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
IAG42_18900  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
IAG42_25850  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
IAG42_36515  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
IAG42_33510  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
IAG42_13205  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
IAG42_14420  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
IAG42_31580  adenine deaminase [KO:K01486] [EC:3.5.4.2]
IAG42_23945  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
IAG42_26770  5'-nucleotidase C-terminal domain-containing protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
IAG42_14185  adenylate kinase [KO:K00939] [EC:2.7.4.3]
IAG42_07890  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
IAG42_29485  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
IAG42_07710  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
IAG42_07720  50S ribosome-binding GTPase [KO:K00956] [EC:2.7.7.4]
IAG42_07715  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
IAG42_33225  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
IAG42_07000  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
IAG42_07005  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
IAG42_22670  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
IAG42_07010  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
IAG42_13410  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
IAG42_31415  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
IAG42_06820  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
IAG42_23415  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
IAG42_30820  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
IAG42_10145  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
IAG42_30815  urease subunit beta [KO:K01429] [EC:3.5.1.5]
IAG42_30810  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
IAG42_10150  ureA; urease subunit gamma [KO:K14048] [EC:3.5.1.5]
IAG42_32865  carbamate kinase [KO:K00926] [EC:2.7.2.2]
IAG42_04910  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sxn00030  Pentose phosphate pathway
sxn00220  Arginine biosynthesis
sxn00250  Alanine, aspartate and glutamate metabolism
sxn00260  Glycine, serine and threonine metabolism
sxn00340  Histidine metabolism
sxn00630  Glyoxylate and dicarboxylate metabolism
sxn00730  Thiamine metabolism
sxn00740  Riboflavin metabolism
sxn00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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