KEGG   PATHWAY: tcc00564
Entry
tcc00564                    Pathway                                
Name
Glycerophospholipid metabolism - Theobroma cacao (cacao)
Class
Metabolism; Lipid metabolism
Pathway map
tcc00564  Glycerophospholipid metabolism
tcc00564

Module
tcc_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:tcc00564]
Other DBs
GO: 0006650
Organism
Theobroma cacao (cacao) [GN:tcc]
Gene
18600884  glycerol-3-phosphate dehydrogenase [NAD(+)] [KO:K00006] [EC:1.1.1.8]
18598912  glycerol-3-phosphate dehydrogenase [NAD(+)] GPDHC1, cytosolic [KO:K00006] [EC:1.1.1.8]
18585727  probable glycerol-3-phosphate dehydrogenase [NAD(+)] 1, cytosolic [KO:K00006] [EC:1.1.1.8]
18587434  glycerol-3-phosphate dehydrogenase [NAD(+)] 2, chloroplastic [KO:K00006] [EC:1.1.1.8]
18586480  glycerol-3-phosphate dehydrogenase SDP6, mitochondrial [KO:K00111] [EC:1.1.5.3]
18607419  glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
18606823  glycerol-3-phosphate acyltransferase, chloroplastic [KO:K00630] [EC:2.3.1.15]
18600590  probable glycerol-3-phosphate acyltransferase 3 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
18614127  probable glycerol-3-phosphate acyltransferase 8 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
18613735  probable glycerol-3-phosphate acyltransferase 3 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
18612163  glycerol-3-phosphate acyltransferase 1 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
18597581  glycerol-3-phosphate 2-O-acyltransferase 6 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
18592227  probable glycerol-3-phosphate acyltransferase 3 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
18586046  glycerol-3-phosphate acyltransferase 5 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
18587833  1-acyl-sn-glycerol-3-phosphate acyltransferase 1, chloroplastic [KO:K00655] [EC:2.3.1.51]
18589822  1-acyl-sn-glycerol-3-phosphate acyltransferase PLS1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
18589824  1-acyl-sn-glycerol-3-phosphate acyltransferase 3 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
18599016  1-acyl-sn-glycerol-3-phosphate acyltransferase 2 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
18608138  probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 5 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
18591334  probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 4 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
18595203  lysophospholipid acyltransferase 1 [KO:K13519] [EC:2.3.1.51 2.3.1.23 2.3.1.-]
18598820  triacylglycerol lipase SDP1 [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
18604977  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
18597842  phosphatidate phosphatase PAH1 [KO:K15728] [EC:3.1.3.4]
18591223  phosphatidate phosphatase PAH2 [KO:K15728] [EC:3.1.3.4]
18604210  lipid phosphate phosphatase 2 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
18609146  lipid phosphate phosphatase 2 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
18609147  lipid phosphate phosphatase 2 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
18601991  putative lipid phosphate phosphatase 3, chloroplastic [KO:K18693] [EC:3.6.1.75 3.1.3.4]
18589123  diacylglycerol kinase 4 [KO:K00901] [EC:2.7.1.107]
18608614  diacylglycerol kinase 5 [KO:K00901] [EC:2.7.1.107]
18604795  diacylglycerol kinase 1 [KO:K00901] [EC:2.7.1.107]
18593804  diacylglycerol kinase 5 [KO:K00901] [EC:2.7.1.107]
18605118  non-specific phospholipase C6 [KO:K01114] [EC:3.1.4.3]
18590507  non-specific phospholipase C1 [KO:K01114] [EC:3.1.4.3]
18589982  non-specific phospholipase C2 [KO:K01114] [EC:3.1.4.3]
18599684  non-specific phospholipase C4 [KO:K01114] [EC:3.1.4.3]
18599683  non-specific phospholipase C3 [KO:K01114] [EC:3.1.4.3]
18587797  phospholipase D alpha 1 [KO:K01115] [EC:3.1.4.4]
18588766  phospholipase D alpha 1 [KO:K01115] [EC:3.1.4.4]
18587798  phospholipase D alpha 1 [KO:K01115] [EC:3.1.4.4]
18610699  phospholipase D delta [KO:K01115] [EC:3.1.4.4]
18614242  phospholipase D beta 2 [KO:K01115] [EC:3.1.4.4]
18607832  phospholipase D delta [KO:K01115] [EC:3.1.4.4]
18606428  phospholipase D gamma 1 [KO:K01115] [EC:3.1.4.4]
18603558  phospholipase D zeta 1 [KO:K01115] [EC:3.1.4.4]
18600515  phospholipase D zeta 2 [KO:K01115] [EC:3.1.4.4]
18591630  phospholipase D delta [KO:K01115] [EC:3.1.4.4]
18595246  phospholipase D alpha 1 [KO:K01115] [EC:3.1.4.4]
18596120  phospholipase D alpha 4 [KO:K01115] [EC:3.1.4.4]
18587705  phospholipase D Z [KO:K16860] [EC:3.1.4.4]
18589439  phospholipase A2-alpha [KO:K01047] [EC:3.1.1.4]
18614249  lysophospholipid acyltransferase LPEAT2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
18591346  lysophospholipid acyltransferase LPEAT1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
18614479  phospholipase A(1) DAD1, chloroplastic [KO:K16818] [EC:3.1.1.32]
18614477  phospholipase A(1) DAD1, chloroplastic [KO:K16818] [EC:3.1.1.32]
18599259  phospholipase A(1) LCAT3 [KO:K22389] [EC:3.1.1.32]
18596419  lecithin-cholesterol acyltransferase-like 4 [KO:K22389] [EC:3.1.1.32]
18588984  acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
18588707  acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
18595774  acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
18601075  glycerophosphodiester phosphodiesterase GDPD1, chloroplastic [KO:K18696] [EC:3.1.4.46]
18610246  glycerophosphodiester phosphodiesterase GDPD6 [KO:K01126] [EC:3.1.4.46]
18604844  glycerophosphodiester phosphodiesterase GDPD6 [KO:K01126] [EC:3.1.4.46]
18592708  probable choline kinase 1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
18587073  probable choline kinase 2 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
18612268  choline-phosphate cytidylyltransferase 2 [KO:K00968] [EC:2.7.7.15]
18610102  choline/ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
18592588  serine decarboxylase [KO:K25193] [EC:4.1.1.-]
18588734  probable ethanolamine kinase [KO:K00894] [EC:2.7.1.82]
18589429  ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
18604331  phosphoethanolamine N-methyltransferase 1 [KO:K05929] [EC:2.1.1.103]
18595435  phosphatidyl-N-methylethanolamine N-methyltransferase [KO:K00550] [EC:2.1.1.71]
18614356  phosphatidate cytidylyltransferase 4, chloroplastic [KO:K00981] [EC:2.7.7.41]
18597264  phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
18593422  phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
18609079  CDP-diacylglycerol--serine O-phosphatidyltransferase 1 [KO:K08730] [EC:2.7.8.29]
18608344  phosphatidylserine decarboxylase proenzyme 2 [KO:K01613] [EC:4.1.1.65]
18606237  phosphatidylserine decarboxylase proenzyme 1, mitochondrial [KO:K01613] [EC:4.1.1.65]
18586302  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2 [KO:K00995] [EC:2.7.8.5]
18612152  uncharacterized LOC18612152 [KO:K01094] [EC:3.1.3.27]
18597124  cardiolipin synthase (CMP-forming), mitochondrial [KO:K08744] [EC:2.7.8.41]
18600475  uncharacterized LOC18600475 [KO:K13511] [EC:2.3.1.-]
18610616  N-acylphosphatidylethanolamine synthase [KO:K13511] [EC:2.3.1.-]
18607542  CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1 [KO:K00999] [EC:2.7.8.11]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
tcc00010  Glycolysis / Gluconeogenesis
tcc00260  Glycine, serine and threonine metabolism
tcc00561  Glycerolipid metabolism
tcc00562  Inositol phosphate metabolism
tcc00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
tcc00565  Ether lipid metabolism
tcc00620  Pyruvate metabolism
KO pathway
ko00564   
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