KEGG   PATHWAY: tge00330
Entry
tge00330                    Pathway                                
Name
Arginine and proline metabolism - Theropithecus gelada (gelada)
Class
Metabolism; Amino acid metabolism
Pathway map
tge00330  Arginine and proline metabolism
tge00330

Module
tge_M00015  Proline biosynthesis, glutamate => proline [PATH:tge00330]
tge_M00047  Creatine pathway [PATH:tge00330]
tge_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:tge00330]
tge_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:tge00330]
tge_M00970  Proline degradation, proline => glutamate [PATH:tge00330]
tge_M00972  Proline metabolism [PATH:tge00330]
Other DBs
GO: 0006525 0006560
Organism
Theropithecus gelada (gelada) [GN:tge]
Gene
112604674  ODC1; ornithine decarboxylase isoform X1 [KO:K01581] [EC:4.1.1.17]
112606506  AGMAT; agmatinase, mitochondrial [KO:K27001]
112606990  CARNS1; carnosine synthase 1 isoform X1 [KO:K14755] [EC:6.3.2.11]
112607185  P4HA3; prolyl 4-hydroxylase subunit alpha-3 isoform X1 [KO:K00472] [EC:1.14.11.2]
112608057  ALDH1B1; aldehyde dehydrogenase X, mitochondrial isoform X1 [KO:K00128] [EC:1.2.1.3]
112608179  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase isoform X1 [KO:K00149] [EC:1.2.1.47 1.2.1.3]
112609421  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [KO:K00286] [EC:1.5.1.2]
112609836  SAT2; diamine acetyltransferase 2 isoform X1 [KO:K00657] [EC:2.3.1.57]
112609860  ALDH3A2; fatty aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
112609895  NOS2; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
112611594  CNDP2; cytosolic non-specific dipeptidase isoform X1 [KO:K08660] [EC:3.4.13.18]
112611596  CNDP1; beta-Ala-His dipeptidase [KO:K05604] [EC:3.4.13.20]
112611985  PRODH2; hydroxyproline dehydrogenase [KO:K11394] [EC:1.5.5.3]
112612271  CKM; creatine kinase M-type [KO:K27382]
112613537  GAMT; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
112614332  GOT2; aspartate aminotransferase, mitochondrial isoform X1 [KO:K14455] [EC:2.6.1.1]
112615444  MAOA; amine oxidase [flavin-containing] A isoform X1 [KO:K00274] [EC:1.4.3.4]
112615671  SMS; spermine synthase isoform X1 [KO:K00802] [EC:2.5.1.22]
112616093  MAOB; amine oxidase [flavin-containing] B isoform X1 [KO:K00274] [EC:1.4.3.4]
112616252  SAT1; diamine acetyltransferase 1 isoform X1 [KO:K00657] [EC:2.3.1.57]
112617023  [KO:K00797] [EC:2.5.1.16]
112617030  [KO:K00797] [EC:2.5.1.16]
112620088  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
112620359  NOS3; nitric oxide synthase, endothelial isoform X1 [KO:K13242] [EC:1.14.13.39]
112622258  AMD1; S-adenosylmethionine decarboxylase proenzyme isoform X1 [KO:K01611] [EC:4.1.1.50]
112622497  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial isoform X1 [KO:K00294] [EC:1.2.1.88]
112622749  ARG1; arginase-1 [KO:K01476] [EC:3.5.3.1]
112624275  LAP3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
112624979  [KO:K01581] [EC:4.1.1.17]
112625716  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
112625911  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
112626208  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase isoform X1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
112627371  [KO:K00933] [EC:2.7.3.2]
112627528  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
112628280  AZIN2; antizyme inhibitor 2 isoform X1 [KO:K01583] [EC:4.1.1.19]
112628447  CKB; creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
112628556  L3HYPDH; trans-3-hydroxy-L-proline dehydratase isoform X1 [KO:K18384] [EC:4.2.1.77]
112628711  PYCR2; pyrroline-5-carboxylate reductase 2 isoform X1 [KO:K00286] [EC:1.5.1.2]
112629215  ARG2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
112630527  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
112630620  PYCR3; pyrroline-5-carboxylate reductase 3 isoform X1 [KO:K00286] [EC:1.5.1.2]
112631109  OAT; ornithine aminotransferase, mitochondrial isoform X1 [KO:K00819] [EC:2.6.1.13]
112631144  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
112631251  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
112631561  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
112631946  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
112633096  PRODH; proline dehydrogenase 1, mitochondrial isoform X1 [KO:K00318] [EC:1.5.5.2]
112633500  SMOX; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
112634095  ALDH2; aldehyde dehydrogenase, mitochondrial isoform X1 [KO:K00128] [EC:1.2.1.3]
112634438  DAO; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
112634545  NOS1; nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
tge00020  Citrate cycle (TCA cycle)
tge00220  Arginine biosynthesis
tge00250  Alanine, aspartate and glutamate metabolism
tge00260  Glycine, serine and threonine metabolism
tge00270  Cysteine and methionine metabolism
tge00310  Lysine degradation
tge00410  beta-Alanine metabolism
tge00470  D-Amino acid metabolism
tge00480  Glutathione metabolism
tge00630  Glyoxylate and dicarboxylate metabolism
tge00650  Butanoate metabolism
tge00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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