KEGG   PATHWAY: tpul00230
Entry
tpul00230                   Pathway                                
Name
Purine metabolism - Tsukamurella pulmonis
Class
Metabolism; Nucleotide metabolism
Pathway map
tpul00230  Purine metabolism
tpul00230

Module
tpul_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:tpul00230]
tpul_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:tpul00230]
tpul_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:tpul00230]
tpul_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:tpul00230]
tpul_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:tpul00230]
tpul_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:tpul00230]
tpul_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:tpul00230]
Other DBs
GO: 0006163 0042278
Organism
Tsukamurella pulmonis [GN:tpul]
Gene
TPB0596_02280  deoD2; purine nucleoside phosphorylase DeoD-type 2 [KO:K03784] [EC:2.4.2.1]
TPB0596_02900  [KO:K01768] [EC:4.6.1.1]
TPB0596_05450  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
TPB0596_05490  [KO:K08289] [EC:6.3.1.21]
TPB0596_05670  nagD; acid sugar phosphatase [KO:K02566] [EC:3.1.3.5]
TPB0596_05770  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
TPB0596_06660  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
TPB0596_09370  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
TPB0596_09380  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
TPB0596_11170  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
TPB0596_11180  [KO:K00088] [EC:1.1.1.205]
TPB0596_11220  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
TPB0596_11820  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
TPB0596_12730  [KO:K03783] [EC:2.4.2.1]
TPB0596_13290  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
TPB0596_13300  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
TPB0596_14630  pgm; phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
TPB0596_14920  nrdE2; ribonucleoside-diphosphate reductase subunit alpha 2 [KO:K00525] [EC:1.17.4.1]
TPB0596_15290  [KO:K00526] [EC:1.17.4.1]
TPB0596_17000  [KO:K00956] [EC:2.7.7.4]
TPB0596_17010  [KO:K00957] [EC:2.7.7.4]
TPB0596_17330  [KO:K01129] [EC:3.1.5.1]
TPB0596_18140  [KO:K00856] [EC:2.7.1.20]
TPB0596_18490  [KO:K07816] [EC:2.7.6.5]
TPB0596_18780  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
TPB0596_19250  [KO:K00942] [EC:2.7.4.8]
TPB0596_22660  [KO:K26110]
TPB0596_24380  [KO:K01081] [EC:3.1.3.5]
TPB0596_24670  [KO:K01239] [EC:3.2.2.1]
TPB0596_25630  [KO:K13481] [EC:1.17.1.4]
TPB0596_25640  [KO:K13482] [EC:1.17.1.4]
TPB0596_25660  guaD; putative guanine deaminase [KO:K01487] [EC:3.5.4.3]
TPB0596_25680  [KO:K14977] [EC:3.5.3.26]
TPB0596_25690  [KO:K16841] [EC:5.1.99.3]
TPB0596_25710  [KO:K01466] [EC:3.5.2.5]
TPB0596_26480  [KO:K01139] [EC:2.7.6.5 3.1.7.2]
TPB0596_26490  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
TPB0596_26740  [KO:K19710] [EC:2.7.7.53]
TPB0596_29990  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
TPB0596_30000  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
TPB0596_30010  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
TPB0596_30720  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
TPB0596_32880  rdgB; non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
TPB0596_33030  [KO:K16840] [EC:4.1.1.97]
TPB0596_33040  [KO:K07127] [EC:3.5.2.17]
TPB0596_33050  [KO:K00365] [EC:1.7.3.3]
TPB0596_36150  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
TPB0596_36410  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
TPB0596_36500  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
TPB0596_37140  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
TPB0596_38900  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
TPB0596_38910  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
TPB0596_39090  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269]
TPB0596_39100  [KO:K00955] [EC:2.7.7.4 2.7.1.25]
TPB0596_39110  [KO:K00957] [EC:2.7.7.4]
TPB0596_39270  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265]
TPB0596_39280  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264]
TPB0596_39360  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
TPB0596_39380  [KO:K01756] [EC:4.3.2.2]
TPB0596_39400  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
TPB0596_41020  [KO:K01768] [EC:4.6.1.1]
TPB0596_42400  [KO:K01768] [EC:4.6.1.1]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
tpul00030  Pentose phosphate pathway
tpul00220  Arginine biosynthesis
tpul00250  Alanine, aspartate and glutamate metabolism
tpul00260  Glycine, serine and threonine metabolism
tpul00340  Histidine metabolism
tpul00630  Glyoxylate and dicarboxylate metabolism
tpul00730  Thiamine metabolism
tpul00740  Riboflavin metabolism
tpul00790  Folate biosynthesis
KO pathway
ko00230   

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