KEGG   PATHWAY: vsi00230
Entry
vsi00230                    Pathway                                
Name
Purine metabolism - Vibrio sinaloensis
Class
Metabolism; Nucleotide metabolism
Pathway map
vsi00230  Purine metabolism
vsi00230

Module
vsi_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:vsi00230]
vsi_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:vsi00230]
vsi_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:vsi00230]
vsi_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:vsi00230]
vsi_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:vsi00230]
vsi_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:vsi00230]
vsi_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:vsi00230]
Other DBs
GO: 0006163 0042278
Organism
Vibrio sinaloensis [GN:vsi]
Gene
MTO69_00200  [KO:K01589] [EC:6.3.4.18]
MTO69_00205  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
MTO69_00275  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
MTO69_00455  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
MTO69_00475  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
MTO69_00485  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
MTO69_00895  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
MTO69_00900  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
MTO69_02285  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
MTO69_02290  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
MTO69_02555  nudF; ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
MTO69_02565  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
MTO69_02845  [KO:K01839] [EC:5.4.2.7]
MTO69_02850  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
MTO69_03035  tet(34); oxytetracycline resistance phosphoribosyltransferase domain-containing protein Tet(34) [KO:K00769] [EC:2.4.2.22]
MTO69_03605  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
MTO69_03875  [KO:K00948] [EC:2.7.6.1]
MTO69_03920  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA [KO:K11751] [EC:3.1.3.5 3.6.1.45]
MTO69_04755  [KO:K21053] [EC:3.5.4.2]
MTO69_04765  [KO:K01129] [EC:3.1.5.1]
MTO69_04770  yfbR; 5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
MTO69_05855  [KO:K01429] [EC:3.5.1.5]
MTO69_06015  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
MTO69_06020  nrdA; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
MTO69_06095  [KO:K01923] [EC:6.3.2.6]
MTO69_07445  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
MTO69_08200  [KO:K00892] [EC:2.7.1.73]
MTO69_08220  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
MTO69_09065  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
MTO69_09290  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
MTO69_09615  ppnN; nucleotide 5'-monophosphate nucleosidase PpnN [KO:K06966] [EC:3.2.2.10 3.2.2.-]
MTO69_09760  pgm; phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [KO:K01835] [EC:5.4.2.2]
MTO69_09865  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
MTO69_09870  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
MTO69_09895  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
MTO69_10195  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
MTO69_10200  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
MTO69_10415  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MTO69_10775  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
MTO69_10875  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
MTO69_10915  yjjX; inosine/xanthosine triphosphatase [KO:K01529]
MTO69_11385  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
MTO69_11535  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
MTO69_11650  apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH [KO:K01525] [EC:3.6.1.41]
MTO69_11850  [KO:K01519] [EC:3.6.1.66]
MTO69_12145  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
MTO69_12155  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
MTO69_12160  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
MTO69_12170  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
MTO69_12360  [KO:K01939] [EC:6.3.4.4]
MTO69_12475  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
MTO69_12950  [KO:K05851] [EC:4.6.1.1]
MTO69_13070  gppA; guanosine-5'-triphosphate,3'-diphosphate diphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MTO69_13755  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
MTO69_14030  [KO:K01081] [EC:3.1.3.5]
MTO69_14310  [KO:K00892] [EC:2.7.1.73]
MTO69_15025  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
MTO69_15730  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
MTO69_16330  [KO:K02083] [EC:3.5.3.9]
MTO69_16335  [KO:K00839] [EC:2.6.1.112]
MTO69_16385  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
MTO69_16390  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
MTO69_16400  [KO:K16840] [EC:4.1.1.97]
MTO69_16405  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
MTO69_16410  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
MTO69_17575  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
MTO69_18500  [KO:K00364] [EC:1.7.1.7]
MTO69_18520  [KO:K00939] [EC:2.7.4.3]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
vsi00030  Pentose phosphate pathway
vsi00220  Arginine biosynthesis
vsi00250  Alanine, aspartate and glutamate metabolism
vsi00260  Glycine, serine and threonine metabolism
vsi00340  Histidine metabolism
vsi00630  Glyoxylate and dicarboxylate metabolism
vsi00730  Thiamine metabolism
vsi00740  Riboflavin metabolism
vsi00790  Folate biosynthesis
KO pathway
ko00230   

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