KEGG   PATHWAY: zof00860
Entry
zof00860                    Pathway                                
Name
Porphyrin metabolism - Zingiber officinale (ginger)
Description
Porphyrins are a group of chemical compounds with the backbone ring structure consisting of four linked pyrrole units. Metal complexes of porphyrins, as well as those of corrinoids with the one-carbon shorter ring structure, play important biological roles. They include iron-containing heme, magnesium-containing chlorophyll, nickel-containing coenzyme F430 and cobalt-containing cobamide (such as vitamin B12 coenzyme) as shown in this map.
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
zof00860  Porphyrin metabolism
zof00860

Module
zof_M00121  Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:zof00860]
Other DBs
GO: 0006778
Organism
Zingiber officinale (ginger) [GN:zof]
Gene
121977205  glutamate--tRNA ligase, cytoplasmic-like [KO:K01885] [EC:6.1.1.17]
122008110  glutamate--tRNA ligase, chloroplastic/mitochondrial-like [KO:K01885] [EC:6.1.1.17]
122051270  glutamate--tRNA ligase, cytoplasmic-like [KO:K01885] [EC:6.1.1.17]
122015962  glutamate--tRNA ligase, chloroplastic/mitochondrial-like [KO:K01885] [EC:6.1.1.17]
122055813  glutamate--tRNA ligase, cytoplasmic-like isoform X1 [KO:K01885] [EC:6.1.1.17]
121972186  glutamate--tRNA ligase, cytoplasmic-like [KO:K01885] [EC:6.1.1.17]
121974883  glutamyl-tRNA reductase 2-like [KO:K02492] [EC:1.2.1.70]
121992913  glutamyl-tRNA reductase 2-like [KO:K02492] [EC:1.2.1.70]
121996909  glutamyl-tRNA reductase 2-like [KO:K02492] [EC:1.2.1.70]
121967578  glutamyl-tRNA reductase 2-like isoform X1 [KO:K02492] [EC:1.2.1.70]
122020185  glutamyl-tRNA reductase 2-like isoform X1 [KO:K02492] [EC:1.2.1.70]
121969753  glutamyl-tRNA reductase 2-like isoform X1 [KO:K02492] [EC:1.2.1.70]
122052816  glutamyl-tRNA reductase 2-like isoform X1 [KO:K02492] [EC:1.2.1.70]
122024935  glutamyl-tRNA reductase 2-like [KO:K02492] [EC:1.2.1.70]
122027132  glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic isoform X1 [KO:K01845] [EC:5.4.3.8]
122030057  glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic isoform X1 [KO:K01845] [EC:5.4.3.8]
122031913  glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic-like [KO:K01845] [EC:5.4.3.8]
122034449  glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic-like [KO:K01845] [EC:5.4.3.8]
122031895  delta-aminolevulinic acid dehydratase, chloroplastic-like [KO:K01698] [EC:4.2.1.24]
122034373  delta-aminolevulinic acid dehydratase, chloroplastic-like [KO:K01698] [EC:4.2.1.24]
122012331  porphobilinogen deaminase, chloroplastic-like isoform X1 [KO:K01749] [EC:2.5.1.61]
122021268  porphobilinogen deaminase, chloroplastic-like isoform X1 [KO:K01749] [EC:2.5.1.61]
122015750  porphobilinogen deaminase, chloroplastic-like isoform X1 [KO:K01749] [EC:2.5.1.61]
122024807  porphobilinogen deaminase, chloroplastic-like isoform X1 [KO:K01749] [EC:2.5.1.61]
122051386  uroporphyrinogen-III synthase, chloroplastic-like isoform X1 [KO:K01719] [EC:4.2.1.75]
122055704  uroporphyrinogen-III synthase, chloroplastic-like isoform X1 [KO:K01719] [EC:4.2.1.75]
122027209  uroporphyrinogen decarboxylase [KO:K01599] [EC:4.1.1.37]
122029587  uroporphyrinogen decarboxylase [KO:K01599] [EC:4.1.1.37]
122050966  uroporphyrinogen decarboxylase 1, chloroplastic-like isoform X1 [KO:K01599] [EC:4.1.1.37]
122055540  uroporphyrinogen decarboxylase 1, chloroplastic-like isoform X1 [KO:K01599] [EC:4.1.1.37]
121991972  oxygen-dependent coproporphyrinogen-III oxidase, chloroplastic-like [KO:K00228] [EC:1.3.3.3]
121995881  oxygen-dependent coproporphyrinogen-III oxidase, chloroplastic-like [KO:K00228] [EC:1.3.3.3]
122010073  protoporphyrinogen oxidase, chloroplastic-like isoform X1 [KO:K00231] [EC:1.3.3.4 1.3.3.15]
122020542  protoporphyrinogen oxidase 2-like isoform X1 [KO:K00231] [EC:1.3.3.4 1.3.3.15]
122015956  protoporphyrinogen oxidase, chloroplastic-like [KO:K00231] [EC:1.3.3.4 1.3.3.15]
122024025  protoporphyrinogen oxidase, mitochondrial-like isoform X1 [KO:K00231] [EC:1.3.3.4 1.3.3.15]
121987827  ferrochelatase-1, chloroplastic-like [KO:K01772] [EC:4.98.1.1 4.99.1.9]
121975633  ferrochelatase-1, chloroplastic-like isoform X1 [KO:K01772] [EC:4.98.1.1 4.99.1.9]
121977019  ferrochelatase-2, chloroplastic-like [KO:K01772] [EC:4.98.1.1 4.99.1.9]
121980046  ferrochelatase-1, chloroplastic-like [KO:K01772] [EC:4.98.1.1 4.99.1.9]
122051441  ferrochelatase-2, chloroplastic-like [KO:K01772] [EC:4.98.1.1 4.99.1.9]
121970560  ferrochelatase-1, chloroplastic-like isoform X1 [KO:K01772] [EC:4.98.1.1 4.99.1.9]
121971996  ferrochelatase-2, chloroplastic-like [KO:K01772] [EC:4.98.1.1 4.99.1.9]
122055656  ferrochelatase-2, chloroplastic-like [KO:K01772] [EC:4.98.1.1 4.99.1.9]
121981588  S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase, chloroplastic-like [KO:K02303] [EC:2.1.1.107]
121985466  S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase, chloroplastic-like isoform X1 [KO:K02303] [EC:2.1.1.107]
121997727  sirohydrochlorin ferrochelatase, chloroplastic-like isoform X1 [KO:K03794] [EC:4.99.1.4]
122037501  sirohydrochlorin ferrochelatase, chloroplastic-like isoform X1 [KO:K03794] [EC:4.99.1.4]
122024375  protoheme IX farnesyltransferase, mitochondrial-like [KO:K02257] [EC:2.5.1.141]
122055639  protoheme IX farnesyltransferase, mitochondrial-like [KO:K02257] [EC:2.5.1.141]
122027346  cytochrome c oxidase assembly protein COX15-like isoform X1 [KO:K02259] [EC:1.17.99.9]
122029647  cytochrome c oxidase assembly protein COX15-like isoform X1 [KO:K02259] [EC:1.17.99.9]
122041946  magnesium-chelatase subunit ChlH, chloroplastic [KO:K03403] [EC:6.6.1.1]
122046471  magnesium-chelatase subunit ChlH, chloroplastic-like [KO:K03403] [EC:6.6.1.1]
122019659  magnesium-chelatase subunit ChlD, chloroplastic-like [KO:K03404] [EC:6.6.1.1]
122022699  magnesium-chelatase subunit ChlD, chloroplastic isoform X1 [KO:K03404] [EC:6.6.1.1]
122050968  magnesium-chelatase subunit ChlI, chloroplastic-like isoform X1 [KO:K03405] [EC:6.6.1.1]
122055542  magnesium-chelatase subunit ChlI, chloroplastic-like isoform X1 [KO:K03405] [EC:6.6.1.1]
122008761  magnesium protoporphyrin IX methyltransferase, chloroplastic-like [KO:K03428] [EC:2.1.1.11]
122015774  magnesium protoporphyrin IX methyltransferase, chloroplastic-like [KO:K03428] [EC:2.1.1.11]
122042525  magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, chloroplastic-like [KO:K04035] [EC:1.14.13.81]
122047043  magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, chloroplastic-like [KO:K04035] [EC:1.14.13.81]
122006205  divinyl chlorophyllide a 8-vinyl-reductase, chloroplastic-like [KO:K19073] [EC:1.3.1.75]
122001944  divinyl chlorophyllide a 8-vinyl-reductase, chloroplastic-like [KO:K19073] [EC:1.3.1.75]
121974820  protochlorophyllide reductase-like [KO:K00218] [EC:1.3.1.33]
122043103  protochlorophyllide reductase [KO:K00218] [EC:1.3.1.33]
122047607  protochlorophyllide reductase-like [KO:K00218] [EC:1.3.1.33]
121967647  protochlorophyllide reductase-like [KO:K00218] [EC:1.3.1.33]
121969686  protochlorophyllide reductase-like [KO:K00218] [EC:1.3.1.33]
122052893  protochlorophyllide reductase-like [KO:K00218] [EC:1.3.1.33]
122045407  chlorophyll synthase, chloroplastic-like isoform X1 [KO:K04040] [EC:2.5.1.62 2.5.1.133]
121980436  chlorophyll synthase, chloroplastic-like [KO:K04040] [EC:2.5.1.62 2.5.1.133]
121984344  chlorophyll synthase, chloroplastic-like [KO:K04040] [EC:2.5.1.62 2.5.1.133]
122040898  chlorophyll synthase, chloroplastic-like isoform X1 [KO:K04040] [EC:2.5.1.62 2.5.1.133]
122011636  chlorophyllase-2-like [KO:K08099] [EC:3.1.1.14]
122011637  chlorophyllase-1-like [KO:K08099] [EC:3.1.1.14]
122016014  chlorophyllase-2-like [KO:K08099] [EC:3.1.1.14]
121972176  chlorophyllase-2-like [KO:K08099] [EC:3.1.1.14]
122016437  chlorophyllase-1-like [KO:K08099] [EC:3.1.1.14]
121988946  chlorophyllide a oxygenase, chloroplastic-like [KO:K13600] [EC:1.14.13.122]
121997891  chlorophyllide a oxygenase, chloroplastic-like [KO:K13600] [EC:1.14.13.122]
122027562  chlorophyll(ide) b reductase NOL, chloroplastic-like isoform X1 [KO:K13606] [EC:1.1.1.294]
122029607  chlorophyll(ide) b reductase NOL, chloroplastic-like isoform X1 [KO:K13606] [EC:1.1.1.294]
122038574  probable chlorophyll(ide) b reductase NYC1, chloroplastic [KO:K13606] [EC:1.1.1.294]
121986397  probable chlorophyll(ide) b reductase NYC1, chloroplastic [KO:K13606] [EC:1.1.1.294]
122020626  7-hydroxymethyl chlorophyll a reductase, chloroplastic-like [KO:K18010] [EC:1.17.7.2]
122024322  7-hydroxymethyl chlorophyll a reductase, chloroplastic-like [KO:K18010] [EC:1.17.7.2]
122042644  protein STAY-GREEN, chloroplastic-like [KO:K22013] [EC:4.99.1.10]
122047150  protein STAY-GREEN, chloroplastic-like [KO:K22013] [EC:4.99.1.10]
122049295  magnesium dechelatase SGRL, chloroplastic-like [KO:K22013] [EC:4.99.1.10]
121983394  protein STAY-GREEN, chloroplastic-like [KO:K22013] [EC:4.99.1.10]
121983395  protein STAY-GREEN, chloroplastic-like [KO:K22013] [EC:4.99.1.10]
122039859  magnesium dechelatase SGRL, chloroplastic-like isoform X1 [KO:K22013] [EC:4.99.1.10]
121989308  pheophorbide a oxygenase, chloroplastic-like [KO:K13071] [EC:1.14.15.17]
121998254  pheophorbide a oxygenase, chloroplastic-like [KO:K13071] [EC:1.14.15.17]
121973772  red chlorophyll catabolite reductase-like [KO:K13545] [EC:1.3.7.12]
121976029  red chlorophyll catabolite reductase-like isoform X1 [KO:K13545] [EC:1.3.7.12]
121977835  red chlorophyll catabolite reductase-like [KO:K13545] [EC:1.3.7.12]
121978528  red chlorophyll catabolite reductase-like [KO:K13545] [EC:1.3.7.12]
121971621  red chlorophyll catabolite reductase-like isoform X1 [KO:K13545] [EC:1.3.7.12]
122056583  geranylgeranyl diphosphate reductase-like [KO:K10960] [EC:1.3.1.83 1.3.1.111]
122025374  geranylgeranyl diphosphate reductase-like [KO:K10960] [EC:1.3.1.83 1.3.1.111]
121981453  geranylgeranyl diphosphate reductase, chloroplastic-like [KO:K10960] [EC:1.3.1.83 1.3.1.111]
122038090  geranylgeranyl diphosphate reductase, chloroplastic-like [KO:K10960] [EC:1.3.1.83 1.3.1.111]
121987593  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
122004409  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
122026239  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
122027454  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
122028667  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
122008160  heme oxygenase 1, chloroplastic-like isoform X1 [KO:K21480] [EC:1.14.15.20]
122031149  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
121979463  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
122031360  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
122033555  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
122034561  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
121982802  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
121970063  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
122000063  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
122016136  heme oxygenase 1, chloroplastic-like isoform X1 [KO:K21480] [EC:1.14.15.20]
122039657  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
122040056  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
121986619  heme oxygenase 1, chloroplastic-like [KO:K21480] [EC:1.14.15.20]
122041944  phytochromobilin:ferredoxin oxidoreductase, chloroplastic-like isoform X1 [KO:K08101] [EC:1.3.7.4]
122046470  phytochromobilin:ferredoxin oxidoreductase, chloroplastic-like isoform X1 [KO:K08101] [EC:1.3.7.4]
121976313  frataxin, mitochondrial [KO:K19054] [EC:1.16.3.1]
122004070  ferritin-2, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122004072  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122004073  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122004079  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122005440  ferritin-4, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122019666  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122027551  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122006949  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122006950  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122006951  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122029886  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122031848  ferritin-4, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
121981504  ferritin-4, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122049625  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122011433  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122035194  ferritin-4, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
121999743  ferritin-1, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122022765  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
121985381  ferritin-4, chloroplastic-like isoform X1 [KO:K00522] [EC:1.16.3.1]
122001157  ferritin-4, chloroplastic-like isoform X1 [KO:K00522] [EC:1.16.3.1]
122016133  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122002687  ferritin-3, chloroplastic-like isoform X1 [KO:K00522] [EC:1.16.3.1]
122002688  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122002689  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122002707  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122002708  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122002710  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
122002711  ferritin-3, chloroplastic-like [KO:K00522] [EC:1.16.3.1]
Compound
C00025  L-Glutamate
C00032  Heme
C00037  Glycine
C00188  L-Threonine
C00194  Cobamide coenzyme
C00430  5-Aminolevulinate
C00486  Bilirubin
C00500  Biliverdin
C00524  Cytochrome c
C00541  Cob(II)alamin
C00748  Siroheme
C00853  Cob(I)alamin
C00931  Porphobilinogen
C00992  Aquacob(III)alamin
C01024  Hydroxymethylbilane
C01051  Uroporphyrinogen III
C01079  Protoporphyrinogen IX
C01708  Hemoglobin
C02139  Chlorophyllide
C02191  Protoporphyrin
C02463  Precorrin 2
C02469  Uroporphyrin III
C02800  4,5-Dioxopentanoate
C02823  Cyanocobalamin
C02880  Protochlorophyllide
C02987  L-Glutamyl-tRNA(Glu)
C03029  Transferrin[Fe(II)]2
C03114  Dimethylbenzimidazole
C03179  Transferrin[Fe(III)]2
C03194  (R)-1-Aminopropan-2-ol
C03263  Coproporphyrinogen III
C03373  Aminoimidazole ribotide
C03516  Magnesium protoporphyrin
C03741  (S)-4-Amino-5-oxopentanoate
C04122  D-1-Aminopropan-2-ol O-phosphate
C04536  Magnesium protoporphyrin monomethyl ester
C04778  N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole
C05306  Chlorophyll a
C05307  Chlorophyll b
C05766  Uroporphyrinogen I
C05767  Uroporphyrin I
C05768  Coproporphyrinogen I
C05769  Coproporphyrin I
C05770  Coproporphyrin III
C05772  Precorrin 3A
C05773  Cobyrinate
C05774  Cobinamide
C05775  alpha-Ribazole
C05777  Coenzyme F430
C05778  Sirohydrochlorin
C05779  Apoferritin
C05780  Apotransferrin
C05781  Oxyhemoglobin
C05782  Myoglobin
C05783  Cytochrome a
C05784  Catalase
C05785  Peroxidase
C05786  (3Z)-Phycocyanobilin
C05787  Bilirubin beta-diglucuronide
C05789  L-Urobilinogen
C05790  I-Urobilinogen
C05791  D-Urobilinogen
C05793  L-Urobilin
C05794  Urobilin
C05795  D-Urobilin
C05797  Pheophytin a
C05798  Bacteriopheophytin
C05912  (3Z)-Phycoerythrobilin
C05913  (3Z)-Phytochromobilin
C06319  Precorrin 6Y
C06320  Precorrin 6X
C06399  Hydrogenobyrinate
C06406  Precorrin 3B
C06407  Precorrin 4
C06408  Precorrin 8X
C06416  Precorrin 5
C06503  Hydrogenobyrinate a,c diamide
C06504  Cob(II)yrinate a,c diamide
C06505  Cob(I)yrinate a,c diamide
C06506  Adenosyl cobyrinate a,c diamide
C06507  Adenosyl cobyrinate hexaamide
C06508  Adenosyl cobinamide
C06509  Adenosyl cobinamide phosphate
C06510  Adenosine-GDP-cobinamide
C11242  Bacteriochlorophyll a
C11243  Bacteriochlorophyll b
C11538  Cobalt-sirohydrochlorin
C11540  Cobalt-precorrin 4
C11542  Cobalt-precorrin 6
C11543  Cobalt-dihydro-precorrin 6
C11545  Cobalt-precorrin 8
C11630  15,16-Dihydrobiliverdin
C11829  13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester
C11830  13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester
C11831  Divinylprotochlorophyllide
C11832  Divinyl chlorophyllide a
C11850  Divinylchlorophyll a
C11851  Zn-Bacteriochlorophyll a
C12147  L-Threonine O-3-phosphate
C14818  Fe2+
C14819  Fe3+
C15670  Heme A
C15672  Heme O
C16242  Cobalt-precorrin 5A
C16243  Cobalt-precorrin 5B
C16244  Cobalt-precorrin 7
C16540  7(1)-Hydroxychlorophyllide a
C16541  Chlorophyllide b
C17401  Cobalt-factor III
C18021  Pheophorbide a
C18022  Red chlorophyll catabolite
C18064  Pyropheophorbide a
C18098  Primary fluorescent chlorophyll catabolite
C18151  7(1)-Hydroxychlorophyll a
C18152  3-Vinylbacteriochlorophyllide a
C18153  3-Hydroxyethylbacteriochlorophyllide a
C18154  3-Hydroxyethylchlorophyllide a
C18155  Bacteriochlorophyllide a
C18156  Bacteriochlorophyllide b
C18157  8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d
C18160  Bacteriochlorophyllide d
C18161  Bacteriochlorophyllide c
C18162  Bacteriochlorophyll d
C18163  Bacteriochlorophyll c
C19608  Ferritin
C20666  5-Oxo-delta-bilirubin
C21217  Geranylgeranyl bacteriochlorophyllide a
C21284  Fe-coproporphyrin III
C21427  8,12-Diethyl-3-vinylbacteriochlorophyllide d
C21428  12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d
C21429  12-Ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d
C21431  8-Ethyl-12-methylbacteriochlorophyllide d
C21432  8,12-Diethylbacteriochlorophyllide d
C21433  12-Ethyl-8-propylbacteriochlorophyllide d
C21434  12-Ethyl-8-isobutylbacteriochlorophyllide d
C21435  Geranylgeranyl bacteriochlorophyllide b
C21510  Nickel-sirohydrochlorin
C21511  Nickel-sirohydrochlorin a,c-diamide
C21512  15,17(3)-Seco-F430-17(3)-acid
C21582  Bacteriochlorophyllide e
C21723  Biliverdin-IX-delta
C21724  Biliverdin-IX-beta
C21764  5-Hydroxybenzimidazole
C21835  12,18-Didecarboxysiroheme
C22338  Dihydro-heme d1
C22339  Heme d1
C22450  5-Methoxybenzimidazole
C22451  5-Methoxy-6-methylbenzimidazole
Reference
PMID:9461500
  Authors
Woodcock SC, Raux E, Levillayer F, Thermes C, Rambach A, Warren MJ.
  Title
Effect of mutations in the transmethylase and dehydrogenase/chelatase domains of sirohaem synthase (CysG) on sirohaem and cobalamin biosynthesis.
  Journal
Biochem J 330:121-9 (1998)
DOI:10.1042/bj3300121
Reference
PMID:10217486
  Authors
Johansson P, Hederstedt L
  Title
Organization of genes for tetrapyrrole biosynthesis in gram--positive bacteria.
  Journal
Microbiology 145 ( Pt 3):529-38 (1999)
DOI:10.1099/13500872-145-3-529
Reference
PMID:10518530
  Authors
Maggio-Hall LA, Escalante-Semerena JC.
  Title
In vitro synthesis of the nucleotide loop of cobalamin by Salmonella typhimurium enzymes.
  Journal
Proc Natl Acad Sci USA 96:11798-803 (1999)
DOI:10.1073/pnas.96.21.11798
Reference
PMID:11007789
  Authors
Roper JM, Raux E, Brindley AA, Schubert HL, Gharbia SE, Shah HN, Warren MJ.
  Title
The enigma of cobalamin (Vitamin B12) biosynthesis in Porphyromonas gingivalis. Identification and characterization of a functional corrin pathway.
  Journal
J Biol Chem 275:40316-23 (2000)
DOI:10.1074/jbc.M007146200
Reference
PMID:12196148
  Authors
Scott AI, Roessner CA.
  Title
Biosynthesis of cobalamin (vitamin B(12)).
  Journal
Biochem Soc Trans 30:613-20 (2002)
DOI:10.1042/bst0300613
Reference
PMID:12195810
  Authors
Warren MJ, Raux E, Schubert HL, Escalante-Semerena JC.
  Title
The biosynthesis of adenosylcobalamin (vitamin B12).
  Journal
Nat Prod Rep 19:390-412 (2002)
DOI:10.1039/b108967f
Reference
PMID:12055304
  Authors
Roessner CA, Huang KX, Warren MJ, Raux E, Scott AI.
  Title
Isolation and characterization of 14 additional genes specifying the anaerobic biosynthesis of cobalamin (vitamin B12) in Propionibacterium freudenreichii (P. shermanii).
  Journal
Microbiology 148:1845-53 (2002)
DOI:10.1099/00221287-148-6-1845
Reference
PMID:11283349
  Authors
Frankenberg N, Mukougawa K, Kohchi T, Lagarias JC.
  Title
Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms.
  Journal
Plant Cell 13:965-78 (2001)
DOI:10.1105/tpc.13.4.965
Reference
PMID:17506685
  Authors
Chew AG, Bryant DA
  Title
Chlorophyll biosynthesis in bacteria: the origins of structural and functional diversity.
  Journal
Annu Rev Microbiol 61:113-29 (2007)
DOI:10.1146/annurev.micro.61.080706.093242
Reference
PMID:16245042
  Authors
Frigaard NU, Chew AG, Li H, Maresca JA, Bryant DA
  Title
Chlorobium tepidum: insights into the structure, physiology, and metabolism of a green sulfur bacterium derived from the complete genome sequence.
  Journal
Photosynth Res 78:93-117 (2003)
DOI:10.1023/B:PRES.0000004310.96189.b4
Reference
PMID:23042036
  Authors
Deery E, Schroeder S, Lawrence AD, Taylor SL, Seyedarabi A, Waterman J, Wilson KS, Brown D, Geeves MA, Howard MJ, Pickersgill RW, Warren MJ
  Title
An enzyme-trap approach allows isolation of intermediates in cobalamin biosynthesis.
  Journal
Nat Chem Biol 8:933-40 (2012)
DOI:10.1038/nchembio.1086
Reference
PMID:23922391
  Authors
Moore SJ, Lawrence AD, Biedendieck R, Deery E, Frank S, Howard MJ, Rigby SE, Warren MJ
  Title
Elucidation of the anaerobic pathway for the corrin component of cobalamin (vitamin B12).
  Journal
Proc Natl Acad Sci U S A 110:14906-11 (2013)
DOI:10.1073/pnas.1308098110
Related
pathway
zof00230  Purine metabolism
zof00250  Alanine, aspartate and glutamate metabolism
zof00260  Glycine, serine and threonine metabolism
zof00740  Riboflavin metabolism
KO pathway
ko00860   
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