1. Oxidoreductases

 2. Transferases

 3. Hydrolases

   3.1  Acting on ester bonds

   3.2  Glycosylases

   3.3  Acting on ether bonds

   3.4  Acting on peptide bonds (peptidases)

   3.5  Acting on carbon-nitrogen bonds, other than peptide bonds

   3.6  Acting on acid anhydrides

     3.6.1  In phosphorus-containing anhydrides

       3.6.1.1  inorganic diphosphatase

       3.6.1.2  trimetaphosphatase

       3.6.1.5  apyrase

       3.6.1.6  nucleoside diphosphate phosphatase

       3.6.1.7  acylphosphatase

       3.6.1.8  ATP diphosphatase

       3.6.1.9  nucleotide diphosphatase

       3.6.1.10  endopolyphosphatase

       3.6.1.11  exopolyphosphatase

       3.6.1.12  dCTP diphosphatase

       3.6.1.13  ADP-ribose diphosphatase

       3.6.1.14  adenosine-tetraphosphatase

       3.6.1.15  nucleoside-triphosphate phosphatase

       3.6.1.16  CDP-glycerol diphosphatase

       3.6.1.17  bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)

       3.6.1.18  FAD diphosphatase

       3.6.1.20  5'-acylphosphoadenosine hydrolase

       3.6.1.21  ADP-sugar diphosphatase

       3.6.1.22  NAD+ diphosphatase

       3.6.1.23  dUTP diphosphatase

       3.6.1.24  nucleoside phosphoacylhydrolase

       3.6.1.25  triphosphatase

       3.6.1.26  CDP-diacylglycerol diphosphatase

       3.6.1.27  undecaprenyl-diphosphate phosphatase

       3.6.1.28  thiamine-triphosphatase

       3.6.1.29  bis(5'-adenosyl)-triphosphatase

       3.6.1.31  phosphoribosyl-ATP diphosphatase

       3.6.1.39  thymidine-triphosphatase

       3.6.1.40  guanosine-5'-triphosphate,3'-diphosphate phosphatase

       3.6.1.41  bis(5'-nucleosyl)-tetraphosphatase (symmetrical)

       3.6.1.42  guanosine-diphosphatase

       3.6.1.43  dolichyldiphosphatase

       3.6.1.44  oligosaccharide-diphosphodolichol diphosphatase

       3.6.1.45  UDP-sugar diphosphatase

       3.6.1.52  diphosphoinositol-polyphosphate diphosphatase

       3.6.1.53  Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase

       3.6.1.54  UDP-2,3-diacylglucosamine diphosphatase

       3.6.1.55  8-oxo-dGTP diphosphatase

       3.6.1.56  2-hydroxy-dATP diphosphatase

       3.6.1.57  UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase

       3.6.1.58  8-oxo-dGDP phosphatase

       3.6.1.59  5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase

       3.6.1.60  diadenosine hexaphosphate hydrolase (AMP-forming)

       3.6.1.61  diadenosine hexaphosphate hydrolase (ATP-forming)

       3.6.1.62  5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase

       3.6.1.63  alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase

       3.6.1.64  inosine diphosphate phosphatase

       3.6.1.65  (d)CTP diphosphatase

       3.6.1.66  XTP/dITP diphosphatase

       3.6.1.67  dihydroneopterin triphosphate diphosphatase

       3.6.1.68  geranyl diphosphate phosphohydrolase

       3.6.1.69  8-oxo-(d)GTP phosphatase

       3.6.1.70  guanosine-5'-diphospho-5'-[DNA] diphosphatase

       3.6.1.71  adenosine-5'-diphospho-5'-[DNA] diphosphatase

       3.6.1.72  DNA-3'-diphospho-5'-guanosine diphosphatase

       3.6.1.73  inosine/xanthosine triphosphatase

       3.6.1.74  mRNA 5'-phosphatase

       3.6.1.75  diacylglycerol diphosphate phosphatase

       3.6.1.76  prenyl-diphosphate phosphatase

       3.6.1.77  coenzyme A diphosphatase

     3.6.2  In sulfonyl-containing anhydrides

     3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement

     3.6.5  Acting on GTP to facilitate cellular and subcellular movement

   3.7  Acting on carbon-carbon bonds

   3.8  Acting on halide bonds

   3.9  Acting on phosphorus-nitrogen bonds

   3.10  Acting on sulfur-nitrogen bonds

   3.11  Acting on carbon-phosphorus bonds

   3.12  Acting on sulfur-sulfur bonds

   3.13  Acting on carbon-sulfur bonds

 4. Lyases

 5. Isomerases

 6. Ligases

 7. Translocases