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ENTRY	nt06024
Name	Valine, leucine and isoleucine degradation
Category	Pathway view; Amino acid metabolism
Pathway	hsa00280 Valine, leucine and isoleucine degradation
Module	hsa_M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA hsa_M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA
Display	drug-target relation   disease type

N00832        MSUD (type Ia)     MSUD (type Ib)     MSUD (type II)     MSUD (type III)   N00851        Isovaleric acidemia     3-Methylcrotonylglycinuria     3-Methylcrotonylglycinuria     MGCA1     HL deficiency   N00852        IBD deficiency     Methacrylic aciduria     MMSDH deficiency   N00856        SBCAD deficiency     MHBD deficiency   N00842        Propionic acidemia     Propionic acidemia     MCE deficiency     MMA mut type

MSUD (type Ia)	H00172	Maple syrup urine disease
MSUD (type Ib)	H00172	Maple syrup urine disease
MSUD (type II)	H00172	Maple syrup urine disease
MSUD (type III)	H02000	Dihydrolipoamide dehydrogenase deficiency
Isovaleric acidemia	H00173	Isovaleric acidemia
3-Methylcrotonylglycinuria	H00181	3-Methylcrotonylglycinuria
MGCA1	H00754	3-Methylglutaconic aciduria
HL deficiency	H00179	3-Hydroxy-3-methylglutaryl-CoA lyase deficiency
IBD deficiency	H01279	Isobutyryl-CoA dehydrogenase deficiency
Methacrylic aciduria	H01349	Methacrylic aciduria
MMSDH deficiency	H02285	Methylmalonate semialdehyde dehydrogenase deficiency
SBCAD deficiency	H00375	SBCAD deficiency
MHBD deficiency	H00925	2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency
Propionic acidemia	H00175	Propionic acidemia
MCE deficiency	H00174	Methylmalonic aciduria
MMA mut type	H00174	Methylmalonic aciduria