KEGG   PATHWAY: mamb04010
Entry
mamb04010                   Pathway                                
Name
MAPK signaling pathway - Megalobrama amblycephala (Wuchang bream)
Description
The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals express at least four distinctly regulated groups of MAPKs, extracellular signal-related kinases (ERK)-1/2, Jun amino-terminal kinases (JNK1/2/3), p38 proteins (p38alpha/beta/gamma/delta) and ERK5, that are activated by specific MAPKKs: MEK1/2 for ERK1/2, MKK3/6 for the p38, MKK4/7 (JNKK1/2) for the JNKs, and MEK5 for ERK5. Each MAPKK, however, can be activated by more than one MAPKKK, increasing the complexity and diversity of MAPK signalling. Presumably each MAPKKK confers responsiveness to distinct stimuli. For example, activation of ERK1/2 by growth factors depends on the MAPKKK c-Raf, but other MAPKKKs may activate ERK1/2 in response to pro-inflammatory stimuli.
Class
Environmental Information Processing; Signal transduction
Pathway map
mamb04010  MAPK signaling pathway
mamb04010

Other DBs
GO: 0000165
Organism
Megalobrama amblycephala (Wuchang bream) [GN:mamb]
Gene
125274988  cacna1aa; LOW QUALITY PROTEIN: voltage-dependent P/Q-type calcium channel subunit alpha-1A [KO:K04344]
125256929  cacna1ab; calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b isoform X1 [KO:K04344]
125252855  cacna1bb; voltage-dependent N-type calcium channel subunit alpha-1B isoform X1 [KO:K04849]
125266723  cacna1ba; calcium channel, voltage-dependent, N type, alpha 1B subunit, a isoform X1 [KO:K04849]
125245652  cacna1c; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1 [KO:K04850]
125280569  cacna1db; voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851]
125256332  cacna1da; calcium channel, voltage-dependent, L type, alpha 1D subunit, a isoform X1 [KO:K04851]
125279483  voltage-dependent R-type calcium channel subunit alpha-1E isoform X1 [KO:K04852]
125250621  cacna1eb; voltage-dependent R-type calcium channel subunit alpha-1E isoform X1 [KO:K04852]
125279615  cacna1fb; calcium channel, voltage-dependent, L type, alpha 1F subunit isoform X1 [KO:K04853]
125280153  cacna1fa; voltage-dependent L-type calcium channel subunit alpha-1D [KO:K04853]
125255129  cacna1g; voltage-dependent T-type calcium channel subunit alpha-1G isoform X1 [KO:K04854]
125269266  cacna1ha; LOW QUALITY PROTEIN: voltage-dependent T-type calcium channel subunit alpha-1H [KO:K04855]
125274417  voltage-dependent T-type calcium channel subunit alpha-1I-like [KO:K04856]
125276034  cacna1ia; voltage-dependent T-type calcium channel subunit alpha-1I isoform X1 [KO:K04856]
125263059  cacna1sa; calcium channel, voltage-dependent, L type, alpha 1S subunit, a isoform X1 [KO:K04857]
125279856  cacna1sb; calcium channel, voltage-dependent, L type, alpha 1S subunit, b [KO:K04857]
125246166  cacna2d1a; voltage-dependent calcium channel subunit alpha-2/delta-1a isoform X1 [KO:K04858]
125253992  LOW QUALITY PROTEIN: voltage-dependent calcium channel subunit alpha-2/delta-1 [KO:K04858]
125263541  cacna2d2b; voltage-dependent calcium channel subunit alpha-2/delta-2b isoform X1 [KO:K04859]
125273627  cacna2d2a; voltage-dependent calcium channel subunit alpha-2/delta-2a isoform X1 [KO:K04859]
125280528  cacna2d3a; voltage-dependent calcium channel subunit alpha-2/delta-3 isoform X1 [KO:K04860]
125256832  cacna2d3; voltage-dependent calcium channel subunit alpha-2/delta-3 isoform X1 [KO:K04860]
125245646  cacna2d4a; voltage-dependent calcium channel subunit alpha-2/delta-4 [KO:K04861]
125247226  cacna2d4b; voltage-dependent calcium channel subunit alpha-2/delta-4 isoform X1 [KO:K04861]
125279347  cacnb1; voltage-dependent L-type calcium channel subunit beta-1 isoform X1 [KO:K04862]
125265204  cacnb2a; voltage-dependent L-type calcium channel subunit beta-2a isoform X1 [KO:K04863]
125259658  cacnb3a; voltage-dependent L-type calcium channel subunit beta-3a isoform X1 [KO:K04864]
125260718  cacnb3b; voltage-dependent L-type calcium channel subunit beta-4 [KO:K04864]
125270203  cacnb4a; voltage-dependent L-type calcium channel subunit beta-4a isoform X1 [KO:K04865]
125274289  cacnb4b; voltage-dependent L-type calcium channel subunit beta-4b isoform X1 [KO:K04865]
125278128  cacng1a; calcium channel, voltage-dependent, gamma subunit 1a [KO:K04866]
125266360  cacng1b; voltage-dependent calcium channel gamma-1 subunit [KO:K04866]
125274423  voltage-dependent calcium channel gamma-2 subunit-like [KO:K04867]
125276133  cacng2a; calcium channel, voltage-dependent, gamma subunit 2a [KO:K04867]
125271236  cacng3b; voltage-dependent calcium channel gamma-3 subunit [KO:K04868]
125272720  cacng3a; voltage-dependent calcium channel gamma-3 subunit [KO:K04868]
125278127  cacng4a; voltage-dependent calcium channel gamma-4 subunit [KO:K04869]
125266368  cacng4b; calcium channel, voltage-dependent, gamma subunit 4b [KO:K04869]
125274045  cacng5a; calcium channel, voltage-dependent, gamma subunit 5a isoform X1 [KO:K04870]
125268429  cacng5b; voltage-dependent calcium channel gamma-5 subunit [KO:K04870]
125242825  cacng6b; voltage-dependent calcium channel gamma-6 subunit [KO:K04871]
125275283  cacng6a; calcium channel, voltage-dependent, gamma subunit 6a [KO:K04871]
125243929  cacng7b; voltage-dependent calcium channel gamma-7 subunit [KO:K04872]
125275282  cacng7a; calcium channel, voltage-dependent, gamma subunit 7a isoform X1 [KO:K04872]
125243269  cacng8b; voltage-dependent calcium channel gamma-4 subunit [KO:K04873]
125275280  cacng8a; calcium channel, voltage-dependent, gamma subunit 8a isoform X1 [KO:K04873]
125278182  prkacab; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
125255428  prkacaa; protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a isoform X1 [KO:K04345] [EC:2.7.11.11]
125256470  prkacba; protein kinase, cAMP-dependent, catalytic, beta a [KO:K04345] [EC:2.7.11.11]
125251891  prkacbb; protein kinase, cAMP-dependent, catalytic, beta b [KO:K04345] [EC:2.7.11.11]
125274046  prkcaa; protein kinase C, alpha, a isoform X1 [KO:K02677] [EC:2.7.11.13]
125268438  prkcab; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
125271228  prkcbb; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
125272719  prkcba; protein kinase C, beta a isoform X1 [KO:K19662] [EC:2.7.11.13]
125242974  prkcg; protein kinase C alpha type [KO:K19663] [EC:2.7.11.13]
125269719  gna12a; guanine nucleotide-binding protein subunit alpha-12a [KO:K04346]
125273852  gng12b; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
125251023  gng12a; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12a [KO:K04347]
125266799  gng14; GGL domain-containing protein [KO:K04347]
125259177  ppp3ccb; protein phosphatase 3, catalytic subunit, gamma isozyme, b isoform X1 [KO:K04348] [EC:3.1.3.16]
125259186  ppp3cb; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
125252654  ppp3ca; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
125265608  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
125266516  ppp3cca; protein phosphatase 3, catalytic subunit, gamma isozyme, a isoform X1 [KO:K04348] [EC:3.1.3.16]
125271895  ppp3r1b; calcineurin subunit B type 1b [KO:K06268]
125277514  ppp3r1a; calcineurin subunit B type 1 [KO:K06268]
125254125  rasgrf1; ras-specific guanine nucleotide-releasing factor 1 [KO:K04349]
125262487  rasgrf2a; ras-specific guanine nucleotide-releasing factor 2 [KO:K12326]
125267518  rasgrf2b; ras-specific guanine nucleotide-releasing factor 2 isoform X1 [KO:K12326]
125253718  rasgrp4; RAS guanyl-releasing protein 4 isoform X1 [KO:K04350]
125263983  RAS guanyl-releasing protein 2 [KO:K12361]
125252910  rasgrp2; RAS guanyl-releasing protein 2 [KO:K12361]
125268731  rasgrp3; ras guanyl-releasing protein 3 isoform X1 [KO:K12362]
125259354  rapgef2b; rap guanine nucleotide exchange factor 2 isoform X1 [KO:K08018]
125272614  rapgef2a; rap guanine nucleotide exchange factor 2 isoform X1 [KO:K08018]
125262238  nf1b; neurofibromin isoform X1 [KO:K08052]
125248208  nf1a; neurofibromin isoform X1 [KO:K08052]
125262369  rasa1b; ras GTPase-activating protein 1 [KO:K04352]
125267468  rasa1a; ras GTPase-activating protein 1 [KO:K04352]
125254716  rasa2; ras GTPase-activating protein 2 isoform X1 [KO:K08053]
125279745  rap1aa; RAP1A, member of RAS oncogene family a [KO:K04353]
125256596  ras-related protein Rap-1b-like [KO:K04353]
125246225  rap1b; ras-related protein Rap-1b [KO:K07836]
125259410  egf; pro-epidermal growth factor [KO:K04357]
125273800  tgfa; protransforming growth factor alpha isoform X1 [KO:K08774]
125259438  fgf1a; putative fibroblast growth factor 1 [KO:K18496]
125253550  fgf1b; fibroblast growth factor 1b [KO:K18496]
125267517  fgf2; fibroblast growth factor 2 [KO:K18497]
125252395  fgf22; fibroblast growth factor 22 [KO:K04358]
125269939  fgf9; fibroblast growth factor 4A isoform X1 [KO:K04358]
125244662  fgf6b; fibroblast growth factor 6b [KO:K04358]
125272363  fgf8b; fibroblast growth factor 8b [KO:K04358]
125252988  fgf10a; fibroblast growth factor 10a [KO:K04358]
125259394  fgf16; fibroblast growth factor 16 [KO:K04358]
125259448  fgf20b; fibroblast growth factor 20b [KO:K04358]
125259497  fgf18b; fibroblast growth factor 18b [KO:K04358]
125272538  fgf20a; fibroblast growth factor 20a [KO:K04358]
125279781  fgf17; fibroblast growth factor 17 [KO:K04358]
125265754  fgf3; fibroblast growth factor 3 [KO:K04358]
125265756  fgf4; fibroblast growth factor 4 [KO:K04358]
125246952  fgf6a; fibroblast growth factor 6a [KO:K04358]
125253816  fgf7; fibroblast growth factor 7 [KO:K04358]
125266992  fgf5; fibroblast growth factor 5 [KO:K04358]
125267262  fgf10b; fibroblast growth factor 10b [KO:K04358]
125275624  fgf18a; fibroblast growth factor 18a isoform X1 [KO:K04358]
125251111  fgf24; fibroblast growth factor 24 isoform X1 [KO:K04358]
125276967  fgf8a; fibroblast growth factor 8 [KO:K04358]
125265755  fgf19; fibroblast growth factor 19 [KO:K22603]
125276387  fgf21; fibroblast growth factor 21 [KO:K22429]
125244656  fgf23; fibroblast growth factor 23 [KO:K22428]
125246745  uncharacterized protein LOC125246745 [KO:K22428]
125273541  ngfb; nerve growth factor isoform X1 [KO:K02582]
125260099  ngfa; neurotrophin-7 [KO:K02582]
125264749  bdnf; brain-derived neurotrophic factor isoform X1 [KO:K04355]
125245370  ntf3; neurotrophin-3 isoform X1 [KO:K04356]
125259323  insb; LOW QUALITY PROTEIN: preproinsulin b [KO:K04526]
125266058  ins; insulin [KO:K04526]
125277562  insulin [KO:K04526]
125245042  igf1; insulin-like growth factor I isoform X1 [KO:K05459]
125265136  igf2a; insulin-like growth factor 2a [KO:K13769]
125247366  igf2b; insulin-like growth factor 2b [KO:K13769]
125263758  platelet-derived growth factor subunit A-like isoform X1 [KO:K04359]
125273321  pdgfbb; putative cyclin-dependent serine/threonine-protein kinase DDB_G0272797/DDB_G0274007 [KO:K04359]
125266909  pdgfab; platelet-derived growth factor alpha polypeptide b isoform X1 [KO:K04359]
125253588  si:ch211-79m20.1; sex-determining region Y protein isoform X1 [KO:K17386]
125258960  pdgfc; platelet-derived growth factor C isoform X1 [KO:K05450]
125248816  pdgfd; platelet-derived growth factor D isoform X1 [KO:K05450]
125256822  csf1a; macrophage colony-stimulating factor 1a isoform X1 [KO:K05453]
125246412  kitlgb; kit ligand b [KO:K05461]
125247404  kitlga; kit ligand a [KO:K05461]
125243192  vegfaa; vascular endothelial growth factor A-A isoform X1 [KO:K05448]
125244347  vegfab; vascular endothelial growth factor Ab isoform X1 [KO:K05448]
125278795  pgfa; placenta growth factor [KO:K16859]
125269007  pgfb; placenta growth factor isoform X1 [KO:K16859]
125272117  vegfc; vascular endothelial growth factor C isoform X1 [KO:K05449]
125257007  vegfd; vascular endothelial growth factor D isoform X1 [KO:K05449]
125245538  hgfa; hepatocyte growth factor a isoform X1 [KO:K05460]
125254287  hepatocyte growth factor [KO:K05460]
125243739  angiopoietin-1-like [KO:K05465]
125275122  angpt1; angiopoietin-1 [KO:K05465]
125278311  angpt2a; angiopoietin-2a isoform X1 [KO:K05466]
125274929  angpt2b; angiopoietin-2b isoform X1 [KO:K05466]
125243569  efna1b; ephrin-A1b [KO:K05462]
125243574  si:dkey-246i14.3; ephrin-A4 [KO:K05462]
125243685  efna3b; ephrin-A3b [KO:K05462]
125252592  efna5a; ephrin-A5b [KO:K05462]
125279531  efna5b; ephrin-A5b isoform X1 [KO:K05462]
125275523  efna3a; ephrin-A3 isoform X1 [KO:K05462]
125275525  efna1a; ephrin-A1a isoform X1 [KO:K05462]
125251024  efna2a; ephrin-A2 isoform X1 [KO:K05462]
125262540  gdnfa; glial cell line-derived neurotrophic factor [KO:K05452]
125267244  gdnfb; glial cell line-derived neurotrophic factor [KO:K05452]
125251154  glial cell line-derived neurotrophic factor [KO:K25414]
125256738  nrtn; neurturin [KO:K25414]
125273283  glial cell line-derived neurotrophic factor [KO:K25415]
125251439  neurturin isoform X1 [KO:K25415]
125257816  LOW QUALITY PROTEIN: epidermal growth factor receptor-like [KO:K04361] [EC:2.7.10.1]
125250587  egfra; epidermal growth factor receptor [KO:K04361] [EC:2.7.10.1]
125255361  erbb2; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-2 [KO:K05083] [EC:2.7.10.1]
125274177  erbb3a; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3a [KO:K05084] [EC:2.7.10.1]
125260816  erbb3b; receptor tyrosine-protein kinase erbB-3b isoform X1 [KO:K05084] [EC:2.7.10.1]
125270579  erbb4b; receptor tyrosine-protein kinase erbB-4 isoform X1 [KO:K05085] [EC:2.7.10.1]
125272833  si:ch73-383l1.1; receptor tyrosine-protein kinase erbB-4 [KO:K05085] [EC:2.7.10.1]
125272835  erbb4a; receptor tyrosine-protein kinase erbB-4 isoform X1 [KO:K05085] [EC:2.7.10.1]
125262353  fgfr1b; fibroblast growth factor receptor 1b isoform X1 [KO:K04362] [EC:2.7.10.1]
125280415  fibroblast growth factor receptor 1-A isoform X1 [KO:K04362] [EC:2.7.10.1]
125276420  fgfr2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
125276568  fgfr3; LOW QUALITY PROTEIN: fibroblast growth factor receptor 3 [KO:K05094] [EC:2.7.10.1]
125252629  fgfr4; fibroblast growth factor receptor 4 isoform X1 [KO:K05095] [EC:2.7.10.1]
125278649  ngfra; tumor necrosis factor receptor superfamily member 16 isoform X1 [KO:K02583]
125243934  nradd; tumor necrosis factor receptor superfamily member 16 [KO:K02583]
125255296  ngfrb; nerve growth factor receptor b isoform X1 [KO:K02583]
125242834  ntrk1; high affinity nerve growth factor receptor isoform X1 [KO:K03176] [EC:2.7.10.1]
125280346  ntrk2a; neurotrophic tyrosine kinase, receptor, type 2a isoform X1 [KO:K04360] [EC:2.7.10.1]
125267895  ntrk2b; neurotrophic tyrosine kinase, receptor, type 2b isoform X1 [KO:K04360] [EC:2.7.10.1]
125263650  insrb; insulin receptor b [KO:K04527] [EC:2.7.10.1]
125251149  insra; insulin receptor a [KO:K04527] [EC:2.7.10.1]
125264449  igf1rb; insulin-like growth factor 1b receptor isoform X1 [KO:K05087] [EC:2.7.10.1]
125253737  igf1ra; insulin-like growth factor 1a receptor isoform X1 [KO:K05087] [EC:2.7.10.1]
125277998  pdgfra; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
125275641  pdgfrb; platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
125252728  csf1rb; macrophage colony-stimulating factor 1 receptor isoform X1 [KO:K05090] [EC:2.7.10.1]
125275639  csf1ra; macrophage colony-stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
125277997  kita; mast/stem cell growth factor receptor kita isoform X1 [KO:K05091] [EC:2.7.10.1]
125272588  kitb; KIT proto-oncogene, receptor tyrosine kinase b isoform X1 [KO:K05091] [EC:2.7.10.1]
125258183  flt3; receptor-type tyrosine-protein kinase FLT3 [KO:K05092] [EC:2.7.10.1]
125258789  kdrl; vascular endothelial growth factor receptor kdr-like isoform X1 [KO:K05096] [EC:2.7.10.1]
125257778  flt1; LOW QUALITY PROTEIN: vascular endothelial growth factor receptor 1 [KO:K05096] [EC:2.7.10.1]
125259137  flt4; vascular endothelial growth factor receptor 3 isoform X1 [KO:K05097] [EC:2.7.10.1]
125277993  kdr; LOW QUALITY PROTEIN: vascular endothelial growth factor receptor 2 [KO:K05098] [EC:2.7.10.1]
125246846  met; hepatocyte growth factor receptor isoform X1 [KO:K05099] [EC:2.7.10.1]
125266198  tek; tyrosine-protein kinase receptor Tie-2 [KO:K05121] [EC:2.7.10.1]
125273478  epha2a; ephrin type-A receptor 2a isoform X1 [KO:K05103] [EC:2.7.10.1]
125259922  epha2b; ephrin type-A receptor 2 [KO:K05103] [EC:2.7.10.1]
125276928  ret; proto-oncogene tyrosine-protein kinase receptor Ret isoform X1 [KO:K05126] [EC:2.7.10.1]
125273837  grb2a; growth factor receptor-bound protein 2a [KO:K04364]
125250125  grb2b; growth factor receptor-bound protein 2b [KO:K04364]
125274479  sos1; son of sevenless homolog 1 isoform X1 [KO:K03099]
125277302  sos2; son of sevenless homolog 2 [KO:K03099]
125265127  hrasb; HRas proto-oncogene, GTPase b [KO:K02833]
125247376  hrasa; HRas proto-oncogene, GTPase a [KO:K02833]
125279450  zgc:55558; GTPase KRas [KO:K07827]
125246538  kras; GTPase KRas isoform X1 [KO:K07827]
125279259  nras; GTPase NRas [KO:K07828]
125264644  rras2; ras-related protein R-Ras2 isoform X1 [KO:K07830]
125277285  rras; ras-related protein R-Ras [KO:K07830]
125270285  mrasa; ras-related protein M-Ras [KO:K07831]
125263680  mrasb; ras-related protein M-Ras [KO:K07831]
125266490  araf; serine/threonine-protein kinase A-Raf [KO:K08845] [EC:2.7.11.1]
125246121  braf; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
125259699  raf1a; LOW QUALITY PROTEIN: raf-1 proto-oncogene, serine/threonine kinase a [KO:K04366] [EC:2.7.11.1]
125256524  raf1b; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
125253954  map2k1; LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
125263787  map2k2a; dual specificity mitogen-activated protein kinase kinase 2a [KO:K04369] [EC:2.7.12.2]
125250873  map2k2b; dual specificity mitogen-activated protein kinase kinase 2b [KO:K04369] [EC:2.7.12.2]
125276554  lamtor3; ragulator complex protein LAMTOR3 [KO:K04370]
125267337  mapk1; mitogen-activated protein kinase 1 isoform X1 [KO:K04371] [EC:2.7.11.24]
125275450  mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
125279338  mknk2b; MAP kinase-interacting serine/threonine-protein kinase 2b isoform X1 [KO:K04372] [EC:2.7.11.1]
125250586  mknk2a; MAP kinase-interacting serine/threonine-protein kinase 2a [KO:K04372] [EC:2.7.11.1]
125256350  mknk1; LOW QUALITY PROTEIN: MAP kinase-interacting serine/threonine-protein kinase 1 [KO:K04372] [EC:2.7.11.1]
125266612  rps6ka3a; ribosomal protein S6 kinase alpha-1 [KO:K04373] [EC:2.7.11.1]
125269144  rps6ka1; ribosomal protein S6 kinase alpha-1 isoform X1 [KO:K04373] [EC:2.7.11.1]
125257578  rps6ka3b; ribosomal protein S6 kinase alpha-3 isoform X1 [KO:K04373] [EC:2.7.11.1]
125261084  rps6kal; ribosomal protein S6 kinase alpha-6 isoform X1 [KO:K04373] [EC:2.7.11.1]
125277432  rps6ka2; ribosomal protein S6 kinase alpha-2 isoform X1 [KO:K04373] [EC:2.7.11.1]
125273291  atf4b; activating transcription factor 4b [KO:K04374]
125274434  atf4a; cyclic AMP-dependent transcription factor ATF-4 [KO:K04374]
125279522  elk1; ETS domain-containing protein Elk-1 isoform X1 [KO:K04375]
125256583  elk4; ETS domain-containing protein Elk-4 isoform X1 [KO:K04376]
125258151  myca; transcriptional regulator Myc-A [KO:K04377]
125251860  mycb; transcriptional regulator Myc-B [KO:K04377]
125254512  srfa; serum response factor a isoform X1 [KO:K04378]
125276515  srfb; serum response factor b isoform X1 [KO:K04378]
125278491  fosab; v-fos FBJ murine osteosarcoma viral oncogene homolog Ab [KO:K04379]
125278492  si:ch211-153j24.3; protein c-Fos isoform X1 [KO:K04379]
125268283  fosaa; protein c-Fos isoform X1 [KO:K04379]
125272541  maptb; microtubule-associated protein tau isoform X1 [KO:K04380]
125255272  mapta; microtubule-associated protein tau isoform X1 [KO:K04380]
125243374  stmn1b; stathmin 1b [KO:K04381]
125275255  stmn1a; stathmin 1a [KO:K04381]
125261869  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
125261870  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
125262001  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
125278200  pla2g4ab; cytosolic phospholipase A2 isoform X1 [KO:K16342] [EC:3.1.1.4]
125245073  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
125246655  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
125266030  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
125266031  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
125266034  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
125266162  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
125266251  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
125266252  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
125266253  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
125266254  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
125266255  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
125266256  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
125266257  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
125266258  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
125266259  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
125266261  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
125266268  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
125266277  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
125266278  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
125266279  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
125266336  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
125250122  pla2g4aa; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
125268789  pla2g4f.2; cytosolic phospholipase A2 delta isoform X1 [KO:K16342] [EC:3.1.1.4]
125268790  pla2g4f.1; cytosolic phospholipase A2 zeta [KO:K16342] [EC:3.1.1.4]
125274751  tnfa; tumor necrosis factor a (TNF superfamily, member 2) [KO:K03156]
125262403  interleukin-1 beta-like [KO:K04519]
125262404  interleukin-1 beta-like [KO:K04519]
125252540  tgfb1b; transforming growth factor beta-1 proprotein [KO:K13375]
125249338  tgfb1a; transforming growth factor, beta 1a isoform X1 [KO:K13375]
125242838  tgfb2; transforming growth factor beta-2 proprotein [KO:K13376]
125275660  tgfb5; transforming growth factor beta-2 proprotein [KO:K13376]
125268277  tgfb3; transforming growth factor beta-3 proprotein [KO:K13377]
125244232  tnfrsf1a; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
125270894  interleukin-1 receptor type 1-like [KO:K04386]
125270896  interleukin-1 receptor type 2-like isoform X1 [KO:K04386]
125270897  interleukin-1 receptor type 1 [KO:K04386]
125248378  interleukin-1 receptor accessory protein isoform X1 [KO:K04723]
125250115  tgfbr1a; TGF-beta receptor type-1a [KO:K04674] [EC:2.7.11.30]
125257625  tgfbr1b; TGF-beta receptor type-1b [KO:K04674] [EC:2.7.11.30]
125243030  tgfbr2b; TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
125270567  tgfbr2l; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
125279072  faslg; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
125268751  fas; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
125259154  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
125271174  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
125271298  rac1l; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
125252961  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
125254945  rac1a; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
125268403  rac1b; ras-related C3 botulinum toxin substrate 1b [KO:K04392]
125260328  ras-related C3 botulinum toxin substrate 1-like isoform X1 [KO:K04392]
125276092  rac2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
125271584  rac3a; ras-related C3 botulinum toxin substrate 3a [KO:K07861]
125255025  rac3b; ras-related C3 botulinum toxin substrate 3b [KO:K07861]
125259709  cdc42l2; cell division cycle 42 like 2 isoform X1 [KO:K04393]
125280834  cdc42l; cell division cycle 42, like [KO:K04393]
125256283  cdc42; cell division control protein 42 homolog isoform X1 [KO:K04393]
125264677  tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
125272552  casp3a; caspase-3a [KO:K02187] [EC:3.4.22.56]
125266884  casp3b; caspase-3b [KO:K02187] [EC:3.4.22.56]
125266535  traf2a; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
125266915  LOW QUALITY PROTEIN: TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
125267992  traf2b; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
125275682  daxx; death domain-associated protein 6 isoform X1 [KO:K02308]
125257785  myd88; myeloid differentiation primary response protein MyD88 [KO:K04729]
125279927  irak1; interleukin-1 receptor-associated kinase 1 isoform X1 [KO:K04730] [EC:2.7.11.1]
125247671  irak4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
125265141  traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
125279667  gadd45ga; growth arrest and DNA-damage-inducible, gamma a [KO:K04402]
125253299  growth arrest and DNA damage-inducible protein GADD45 gamma-like [KO:K04402]
125273851  gadd45ab; growth arrest and DNA-damage-inducible, alpha, b [KO:K04402]
125251021  gadd45aa; growth arrest and DNA-damage-inducible, alpha, a [KO:K04402]
125256835  gadd45ba; growth arrest and DNA-damage-inducible, beta a [KO:K04402]
125251371  gadd45bb; growth arrest and DNA-damage-inducible, beta b [KO:K04402]
125253301  growth arrest and DNA damage-inducible protein GADD45 gamma [KO:K04402]
125274426  tab1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
125278955  tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
125265449  ecsit; evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial [KO:K04405]
125268703  map4k3b; mitogen-activated protein kinase kinase kinase kinase 3 isoform X1 [KO:K04406] [EC:2.7.11.1]
125256862  map4k3a; mitogen-activated protein kinase kinase kinase kinase 3 isoform X1 [KO:K04406] [EC:2.7.11.1]
125261079  si:zfos-2326c3.2; misshapen-like kinase 1 isoform X1 [KO:K04407] [EC:2.7.11.1]
125254068  pak1; serine/threonine-protein kinase PAK 1 isoform X1 [KO:K04409] [EC:2.7.11.1]
125263180  pak2b; serine/threonine-protein kinase PAK 2b isoform X1 [KO:K04410] [EC:2.7.11.1]
125251357  pak2a; serine/threonine-protein kinase PAK 2a [KO:K04410] [EC:2.7.11.1]
125274865  stk3; serine/threonine-protein kinase 3 [KO:K04412]
125252873  map4k6; mitogen-activated protein kinase kinase kinase kinase 6 [KO:K04414] [EC:2.7.11.1]
125265440  map4k2; mitogen-activated protein kinase kinase kinase kinase 2 isoform X1 [KO:K04414] [EC:2.7.11.1]
125255242  map3k8; mitogen-activated protein kinase kinase kinase 8 [KO:K04415] [EC:2.7.11.25]
125255879  map3k1; mitogen-activated protein kinase kinase kinase 1 isoform X1 [KO:K04416] [EC:2.7.11.25]
125264245  mitogen-activated protein kinase kinase kinase 11 [KO:K04419] [EC:2.7.11.25]
125274238  map3k2; mitogen-activated protein kinase kinase kinase 2 [KO:K04420] [EC:2.7.11.25]
125276864  map3k3; mitogen-activated protein kinase kinase kinase 3 [KO:K04421] [EC:2.7.11.25]
125257583  map3k22; mitogen-activated protein kinase kinase kinase 22 [KO:K04421] [EC:2.7.11.25]
125277287  map3k9; mitogen-activated protein kinase kinase kinase 9 [KO:K04417] [EC:2.7.11.25]
125254091  map3k10; mitogen-activated protein kinase kinase kinase 10 isoform X1 [KO:K04418] [EC:2.7.11.25]
125276863  map3k21; mitogen-activated protein kinase kinase kinase 21 isoform X1 [KO:K17534] [EC:2.7.11.25]
125269670  map3k12; mitogen-activated protein kinase kinase kinase 12 [KO:K04423] [EC:2.7.11.25]
125270788  si:ch211-45c16.2; mitogen-activated protein kinase kinase kinase 13 isoform X1 [KO:K04422] [EC:2.7.11.25]
125274155  protein kinase Npk isoform X1 [KO:K04424] [EC:2.7.11.25]
125269809  map3k20a; mitogen-activated protein kinase kinase kinase 20 isoform X1 [KO:K04424] [EC:2.7.11.25]
125242985  si:ch211-1i11.3; mitogen-activated protein kinase kinase kinase 5 isoform X1 [KO:K04426] [EC:2.7.11.25]
125278830  map3k5; mitogen-activated protein kinase kinase kinase 5 isoform X1 [KO:K04426] [EC:2.7.11.25]
125278037  map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
125277165  map3k4; mitogen-activated protein kinase kinase kinase 4 isoform X1 [KO:K04428] [EC:2.7.11.25]
125278504  taok2a; serine/threonine-protein kinase TAO2 isoform X1 [KO:K04429] [EC:2.7.11.1]
125252578  taok1b; serine/threonine-protein kinase TAO1 [KO:K04429] [EC:2.7.11.1]
125248121  taok1a; serine/threonine-protein kinase TAO1 [KO:K04429] [EC:2.7.11.1]
125266802  taok3b; serine/threonine-protein kinase TAO3 isoform X1 [KO:K04429] [EC:2.7.11.1]
125267367  taok3a; serine/threonine-protein kinase TAO3 [KO:K04429] [EC:2.7.11.1]
125255606  taok2b; serine/threonine-protein kinase TAO2 isoform X1 [KO:K04429] [EC:2.7.11.1]
125274581  map2k4a; dual specificity mitogen-activated protein kinase kinase 4a isoform X1 [KO:K04430] [EC:2.7.12.2]
125255358  map2k4b; dual specificity mitogen-activated protein kinase kinase 4b isoform X1 [KO:K04430] [EC:2.7.12.2]
125272001  map2k7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
125255310  map2k6; dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
125265742  mapk8ip1b; C-Jun-amino-terminal kinase-interacting protein 1 [KO:K04434]
125247612  mapk8ip1a; C-Jun-amino-terminal kinase-interacting protein 1a isoform X1 [KO:K04434]
125254442  mapk8ip2; C-Jun-amino-terminal kinase-interacting protein 2 isoform X1 [KO:K04435]
125279227  mapk8ip3; C-Jun-amino-terminal kinase-interacting protein 3 isoform X1 [KO:K04436]
125259569  flna; filamin-A [KO:K04437]
125252400  crkl; crk-like protein [KO:K04438]
125248369  crk; adapter molecule crk [KO:K04438]
125264588  arrb2b; arrestin, beta 2b [KO:K04439]
125249630  arrb1; beta-arrestin-1 [KO:K04439]
125260080  arrb2a; arrestin, beta 2a isoform X1 [KO:K04439]
125252240  mapk9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
125252441  mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
125255077  mapk8b; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
125277047  mapk8a; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
125279668  mapk13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
125246180  mapk12b; mitogen-activated protein kinase 12b isoform X1 [KO:K04441] [EC:2.7.11.24]
125246181  mapk11; mitogen-activated protein kinase 11 isoform X1 [KO:K04441] [EC:2.7.11.24]
125279793  mapk14a; mitogen-activated protein kinase 14A isoform X1 [KO:K04441] [EC:2.7.11.24]
125254075  mapk12a; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
125257055  mapk14b; LOW QUALITY PROTEIN: mitogen-activated protein kinase 14B [KO:K04441] [EC:2.7.11.24]
125260456  zgc:171775; STKc_p38 domain-containing protein [KO:K04441] [EC:2.7.11.24]
125267626  mapkapk5; MAP kinase-activated protein kinase 5 [KO:K04442] [EC:2.7.11.1]
125280223  mapkapk2b; MAP kinase-activated protein kinase 2b [KO:K04443] [EC:2.7.11.1]
125256441  mapkapk2a; MAP kinase-activated protein kinase 2 [KO:K04443] [EC:2.7.11.1]
125256230  mapkapk3; MAP kinase-activated protein kinase 3 [KO:K04444] [EC:2.7.11.1]
125269375  rps6ka5; ribosomal protein S6 kinase alpha-5 [KO:K04445] [EC:2.7.11.1]
125267757  rps6ka4; ribosomal protein S6 kinase alpha-4 [KO:K16510] [EC:2.7.11.1]
125276581  cdc25b; M-phase inducer phosphatase 2 [KO:K05866] [EC:3.1.3.48]
125275441  nfatc1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
125264815  nfatc3a; LOW QUALITY PROTEIN: nuclear factor of activated T-cells, cytoplasmic 3 [KO:K17333]
125247411  nfatc3b; nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 [KO:K17333]
125279071  jun; transcription factor AP-1 [KO:K04448]
125266201  june; LOW QUALITY PROTEIN: junE proto-oncogene, AP-1 transcription factor subunit [KO:K04448]
125250608  jund; transcription factor jun-D [KO:K04449]
125269821  atf2; cyclic AMP-dependent transcription factor ATF-2 isoform X1 [KO:K04450]
125265599  cellular tumor antigen p53-like [KO:K04451]
125266618  tp53; cellular tumor antigen p53 isoform X1 [KO:K04451]
125273397  ddit3; DNA damage-inducible transcript 3 protein [KO:K04452]
125277965  max; protein max isoform X1 [KO:K04453]
125262373  mef2ca; myocyte enhancer factor 2ca isoform X1 [KO:K04454]
125267473  mef2cb; myocyte enhancer factor 2cb isoform X1 [KO:K04454]
125266299  hspb1; heat shock protein beta-1 [KO:K04455]
125267091  hspb15; heat shock protein, alpha-crystallin-related, b15 [KO:K04455]
125262568  akt2l; v-akt murine thymoma viral oncogene homolog 2, like [KO:K04456] [EC:2.7.11.1]
125278141  RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
125271808  akt3b; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
125253756  akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
125269260  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
125276757  akt3a; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
125277780  ppm1ab; LOW QUALITY PROTEIN: protein phosphatase, Mg2+/Mn2+ dependent, 1Ab [KO:K04457] [EC:3.1.3.16]
125253184  ppm1nb; protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative) [KO:K04457] [EC:3.1.3.16]
125248963  ppm1na; protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative) [KO:K04457] [EC:3.1.3.16]
125277067  ppm1aa; protein phosphatase 1A isoform X1 [KO:K04457] [EC:3.1.3.16]
125245718  ptprr; tyrosine-protein phosphatase non-receptor type 7 [KO:K04458] [EC:3.1.3.48]
125264984  ptpn5; tyrosine-protein phosphatase non-receptor type 5 isoform X1 [KO:K18018] [EC:3.1.3.48]
125259015  dusp1; dual specificity protein phosphatase 1 [KO:K21278] [EC:3.1.3.16 3.1.3.48]
125252740  dusp4; dual specificity protein phosphatase 4 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
125245407  dusp16; dual specificity protein phosphatase 16 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
125280102  dusp2; LOW QUALITY PROTEIN: dual specificity protein phosphatase 2 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
125253493  dusp5; dual specificity protein phosphatase 5 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
125247957  dusp8a; dual specificity protein phosphatase 8 isoform X1 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
125256247  dusp7; dual specificity protein phosphatase 7 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
125247340  dusp6; dual specificity protein phosphatase 6 [KO:K21946] [EC:3.1.3.16 3.1.3.48]
125278557  dusp10; dual specificity protein phosphatase 10 [KO:K20216] [EC:3.1.3.16 3.1.3.48]
125271128  dusp3b; dual specificity protein phosphatase 3b [KO:K17614] [EC:3.1.3.16 3.1.3.48]
125255595  dusp3a; dual specificity protein phosphatase 3 [KO:K17614] [EC:3.1.3.16 3.1.3.48]
125248312  ppp5c; serine/threonine-protein phosphatase 5 [KO:K04460] [EC:3.1.3.16]
125254975  ppm1bb; protein phosphatase 1bb isoform X1 [KO:K04461] [EC:3.1.3.16]
125276768  ppm1ba; protein phosphatase 1B isoform X1 [KO:K04461] [EC:3.1.3.16]
125262170  hspa8; heat shock cognate 71 kDa protein [KO:K03283]
125278887  heat shock 70 kDa protein-like [KO:K03283]
125279678  LOW QUALITY PROTEIN: heat shock 70 kDa protein-like [KO:K03283]
125279684  heat shock 70 kDa protein [KO:K03283]
125279692  heat shock 70 kDa protein [KO:K03283]
125279699  heat shock 70 kDa protein [KO:K03283]
125279821  hspa1b; heat shock 70 kDa protein-like [KO:K03283]
125248508  hsc70; heat shock cognate 71 kDa protein [KO:K03283]
125275396  heat shock 70 kDa protein [KO:K03283]
125275403  heat shock 70 kDa protein [KO:K03283]
125275406  heat shock 70 kDa protein [KO:K03283]
125249726  hspa8b; heat shock protein family A (Hsp70) member 8b [KO:K03283]
125248870  mecom; MDS1 and EVI1 complex locus protein EVI1-A isoform X1 [KO:K04462] [EC:2.1.1.367]
125264788  map2k5; dual specificity mitogen-activated protein kinase kinase 5 isoform X1 [KO:K04463] [EC:2.7.12.2]
125255330  mapk7; LOW QUALITY PROTEIN: mitogen-activated protein kinase 7 [KO:K04464] [EC:2.7.11.24]
125260026  nr4a1; nuclear receptor subfamily 4 group A member 1 isoform X1 [KO:K04465]
125258494  uncharacterized protein LOC125258494 isoform X1 [KO:K04466] [EC:2.7.11.25]
125272060  map3k14a; mitogen-activated protein kinase kinase kinase 14 isoform X1 [KO:K04466] [EC:2.7.11.25]
125276913  chuk; inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
125279685  ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
125260117  ikbkg; NF-kappa-B essential modulator isoform X1 [KO:K07210]
125278531  nlk1; nemo-like kinase, type 1 [KO:K04468] [EC:2.7.11.24]
125249494  nlk2; serine/threonine-protein kinase NLK [KO:K04468] [EC:2.7.11.24]
125259295  nfkb1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
125276828  nuclear factor NF-kappa-B p100 subunit-like isoform X1 [KO:K04469]
125264241  rela; transcription factor p65 isoform X1 [KO:K04735]
125248777  relb; transcription factor RelB [KO:K09253]
Compound
C00076  Calcium cation
C00165  Diacylglycerol
C00338  Lipopolysaccharide
C00575  3',5'-Cyclic AMP
C01245  D-myo-Inositol 1,4,5-trisphosphate
Reference
PMID:11749383
  Authors
Chen Z, Gibson TB, Robinson F, Silvestro L, Pearson G, Xu B, Wright A, Vanderbilt C, Cobb MH.
  Title
MAP kinases.
  Journal
Chem Rev 101:2449-76 (2001)
DOI:10.1021/cr000241p
Reference
PMID:12191611
  Authors
Tanoue T, Nishida E.
  Title
Docking interactions in the mitogen-activated protein kinase cascades.
  Journal
Pharmacol Ther 93:193-202 (2002)
DOI:10.1016/S0163-7258(02)00188-2
Reference
PMID:12947395
  Authors
Dent P, Yacoub A, Fisher PB, Hagan MP, Grant S.
  Title
MAPK pathways in radiation responses.
  Journal
Oncogene 22:5885-96 (2003)
DOI:10.1038/sj.onc.1206701
Reference
PMID:12676795
  Authors
Huang EJ, Reichardt LF.
  Title
Trk receptors: roles in neuronal signal transduction.
  Journal
Annu Rev Biochem 72:609-42 (2003)
DOI:10.1146/annurev.biochem.72.121801.161629
Reference
PMID:11369511
  Authors
Harper SJ, LoGrasso P.
  Title
Signalling for survival and death in neurones: the role of stress-activated kinases, JNK and p38.
  Journal
Cell Signal 13:299-310 (2001)
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Takeda K, Ichijo H
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Neuronal p38 MAPK signalling: an emerging regulator of cell fate and function in the nervous system.
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Genes Cells 7:1099-111 (2002)
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Yang SH, Sharrocks AD, Whitmarsh AJ.
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Transcriptional regulation by the MAP kinase signaling cascades.
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Gene 320:3-21 (2003)
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Zhu X, Lee HG, Raina AK, Perry G, Smith MA.
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The role of mitogen-activated protein kinase pathways in Alzheimer's disease.
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Neurosignals 11:270-81 (2002)
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Cho H, Lee J, Kwak NJ, Lee KH, Rha S, Kim YH, Cho YY, Yang KH, Kim K, Lim Y.
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Silica induces nuclear factor-kappaB activation through TAK1 and NIK in Rat2 cell line.
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Toxicol Lett 143:323-30 (2003)
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Lemmon MA, Schlessinger J
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Cell signaling by receptor tyrosine kinases.
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Cell 141:1117-34 (2010)
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Skaper SD
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The neurotrophin family of neurotrophic factors: an overview.
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Methods Mol Biol 846:1-12 (2012)
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Tumor necrosis factor.
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Cancer Lett 328:222-5 (2013)
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Newton K, Dixit VM
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Signaling in innate immunity and inflammation.
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Cold Spring Harb Perspect Biol 4:a006049 (2012)
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Gaestel M, Kotlyarov A, Kracht M
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Targeting innate immunity protein kinase signalling in inflammation.
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Nat Rev Drug Discov 8:480-99 (2009)
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Cell type-specific function of TAK1 in innate immune signaling.
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Trends Immunol 34:307-16 (2013)
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Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
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Biochim Biophys Acta 1843:2563-2582 (2014)
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