KEGG ORTHOLOGY: K05762

ORTHOLOGY: K05762

Entry

K05762                      KO

Symbol

RDX

Name

radixin

Pathway

map04530

Tight junction

map04810

Regulation of actin cytoskeleton

map05205

Proteoglycans in cancer

map05206

MicroRNAs in cancer

Disease

H00605

Deafness, autosomal recessive

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    K05762  RDX; radixin
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05762  RDX; radixin
09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K05762  RDX; radixin
   05205 Proteoglycans in cancer
    K05762  RDX; radixin
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K05762  RDX; radixin
   04147 Exosome
    K05762  RDX; radixin
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Ezrin/Radixin/Moesin
     K05762  RDX; radixin
Exosome [BR:ko04147]
Exosomal proteins
  Proteins found in most exosomes
   K05762  RDX; radixin

Other DBs

TC:

8.A.25.1

Genes

HSA:

5962(RDX)

PPS:	100989730(RDX)

GGO:	101126000(RDX)

PON:	100453730(RDX)

PPYG:

129007105(RDX)

NLE:	100601297(RDX)

HMH:	116476910(RDX)

SSYN:

129479620(RDX)

MCC:	709018(RDX)

MCF:	101865352(RDX)

MTHB:

126935789

MNI:	105493642(RDX)

CSAB:

103248423(RDX)

CATY:

105588719(RDX)

PANU:

101025806(RDX)

TGE:	112606121(RDX)

MLEU:

105548213(RDX)

RRO:	104660837(RDX)

RBB:	108536468(RDX)

TFN:	117079987(RDX)

PTEH:

111540115(RDX)

CANG:

105500992(RDX)

CJC:	100405284(RDX)

SBQ:	101037449(RDX)

CIMI:

108316930(RDX)

ANAN:

105729641(RDX)

CSYR:

103258876(RDX)

MMUR:

105876134(RDX)

LCAT:

123641723(RDX)

OGA:	100956512(RDX)

MMU:	19684(Rdx)

MCAL:

110300986(Rdx)

MPAH:

110327234(Rdx)

RNO:	315655(Rdx)

MCOC:

116072668(Rdx)

ANU:	117699413(Rdx)

ASYL:

127689074(Rdx)

MUN:	110550934(Rdx)

CGE:	100752135(Rdx)

MAUA:

101832354(Rdx)

PROB:

127231736(Rdx)

PLEU:

114690265(Rdx) 114696029

MORG:

121438204(Rdx)

MFOT:

126510020

AAMP:

119810427(Rdx)

NGI:	103733898(Rdx)

HGL:	101700282 101713980(Rdx)

CPOC:

100719090(Rdx)

CCAN:

109685688 109685693(Rdx)

DORD:

105980787(Rdx)

DSP:	122110202(Rdx)

PLOP:

125349558(Rdx)

NCAR:

124958285 124970970

MMMA:

107145878(Rdx)

ITI:	101970384(Rdx)

OCU:

100341234

OPI:	101533563(RDX)

TUP:	102473546(RDX)

GVR:	103604456(RDX)

CFA:	479446(RDX)

CLUD:

112671371(RDX)

VVP:	112925966(RDX)

VLG:	121500178(RDX)

NPO:	129496711(RDX)

AML:	100471426(RDX)

UMR:	103662411(RDX)

UAH:	113260085(RDX)

UAR:	123792543(RDX)

ELK:

111153884

LLV:

125078203

MPUF:

101680552(RDX)

MNP:	132028605(RDX)

MLK:	131835552(RDX)

NVS:	122912215(RDX)

ORO:	101381942(RDX)

EJU:	114211302(RDX)

ZCA:	113913797(RDX)

MLX:	118013204(RDX)

NSU:	110586366(RDX)

LWW:	102731139(RDX)

FCA:	101090715(RDX)

PYU:	121035357(RDX)

PCOO:

112864888(RDX)

PBG:	122482929(RDX)

PVIV:

125176808(RDX)

LRUF:

124504938

LGF:	123600619(RDX)

AJU:

106984051

PTG:	102956919(RDX)

PPAD:

109278687(RDX)

PUC:

125910109

PLEZ:

122199328(RDX)

HHV:	120229862(RDX)

BTA:	517111(RDX)

BOM:	102278956(RDX)

BIU:	109569566(RDX)

BBUB:

102400173(RDX)

BBIS:

105005020(RDX)

CHX:	102168557(RDX)

OAS:	101106875(RDX)

BTAX:

128059812(RDX)

CSUM:

138092951(RDX)

ODA:	120876232(RDX)

CCAD:

122449464(RDX)

MREE:

136174994(RDX)

OVR:	110122467(RDX)

MBEZ:

129554308(RDX)

SSC:	494457(RDX)

CFR:	102513121(RDX)

CBAI:

105080323(RDX)

CDK:	105096591(RDX)

VPC:	102535240(RDX)

BACU:

102998582(RDX)

BMUS:

118899116(RDX)

LVE:	103074405(RDX)

OOR:	101290253(RDX)

LALB:

132526289(RDX)

DLE:	111168033(RDX)

PCAD:

102993531(RDX)

PSIU:

116757830(RDX)

NASI:

112405723(RDX)

ECB:	100061858(RDX)

EPZ:	103556588(RDX)

EAI:	106833232(RDX)

MYB:	102248215(RDX)

MYD:	102758541(RDX)

MMYO:

118664443(RDX)

MLF:	102430982(RDX)

MDT:	132240604(RDX)

MYUM:

139017481(RDX)

PKL:	118713595(RDX)

EFUS:

103303067(RDX)

MNA:	107529991(RDX)

DRO:	112314186(RDX)

SHON:

118988233(RDX)

AJM:	119062810(RDX)

PDIC:

114498574(RDX)

PHAS:

123818031(RDX)

MMF:	118627915(RDX)

PPAM:

129085899(RDX)

HAI:	109388703(RDX)

RFQ:	117030286(RDX)

PALE:

102898450(RDX)

PGIG:

120607120(RDX)

PVP:	105295655(RDX)

RAY:	107498251(RDX)

MJV:	108404241 108407034(RDX)

TOD:	119240651(RDX)

SARA:

101537128(RDX)

SFUM:

130016794(RDX)

SETR:

126001937 126016130(RDX)

LAV:	100665532(RDX)

TMU:

101342268

ETF:	101647335(RDX)

DNM:	101444151(RDX)

MDO:	100026658(RDX)

GAS:	123241636(RDX)

SHR:	100924383(RDX)

AFZ:

127554964

PCW:	110214954(RDX)

TVP:	118827965 118835406(RDX)

PBRV:

138155055(RDX)

OAA:	100076248(RDX)

TACU:

119941225(RDX)

GGA:	395511(RDX)

PCOC:

116237210(RDX)

MGP:	100549813(RDX)

CJO:	107308347(RDX)

TPAI:

128074940(RDX)

LMUT:

125688828(RDX)

NMEL:

110389532(RDX)

APLA:

101794726(RDX)

ACYG:

106040387(RDX)

CATA:

118246018(RDX)

AFUL:

116485929(RDX)

TGU:	100228191(RDX)

LSR:	110468109(RDX)

SCAN:

103827299(RDX)

PMOA:

120506579(RDX)

OTC:	121341074(RDX)

PRUF:

121364141(RDX)

ATRC:

139593317(RDX)

GFR:	102042609(RDX)

FAB:	101821767(RDX)

OMA:	130253743(RDX)

PHI:	102100105(RDX)

PMAJ:

107206381(RDX)

CCAE:

111924017(RDX)

CCW:	104690038(RDX)

CBRC:

103611222(RDX)

ACOE:

138109884(RDX)

ETL:	114058013(RDX)

ZAB:	102063467(RDX)

ZLE:	135450103(RDX)

ACHL:

103811021

SVG:	106854014(RDX)

MMEA:

130574944(RDX)

HRT:	120747727(RDX)

SATI:

136357605(RDX)

CCIC:

134041191(RDX)

FPG:	101920917(RDX)

FCH:	102053921(RDX)

CCRI:

104160123

NNT:

104405784

SHAB:

115604601(RDX)

ACUN:

113476034(RDX)

TALA:

104359328(RDX)

ACHC:

115353461(RDX)

HALD:

104318442

HLE:	104834930(RDX)

AGEN:

126048183

HHAR:

128153537(RDX)

GCL:

127013374

CSTI:

104553427(RDX)

LDI:	104344913(RDX)

MNB:	103770960(RDX)

DPUB:

104303382(RDX)

PPUS:

135190212(RDX)

AVIT:

104276917

BRHI:

104492355(RDX)

EGZ:	104134725(RDX)

NNI:	104023050(RDX)

PCRI:

104035831

PCAO:

104044997

PADL:

103926399(RDX)

AFOR:

103901690(RDX)

FGA:	104077450(RDX)

GSTE:

104253406(RDX)

CLV:	102085561(RDX)

MUI:	104538989(RDX)

PGUU:

104471111

PLET:

104619058(RDX)

EHS:

104510129

CMAC:

104477163

CUCA:

104055331(RDX)

TEO:	104372041(RDX)

BREG:

104641341

OHA:	104333053(RDX)

ACAR:

104523000

CPEA:

104390289(RDX)

CVF:	104288144(RDX)

RTD:	128906150(RDX)

CRID:

134513629(RDX)

AAM:	106500446(RDX)

AROW:

112968347(RDX)

NPD:	112943755(RDX)

TGT:	104576004(RDX)

DNE:	112989887(RDX)

SCAM:

104149898(RDX)

ASN:	102376401(RDX)

AMJ:	106736891(RDX)

CPOO:

109306689(RDX)

GGN:	109302719(RDX)

PSS:	102454871(RDX)

CMY:	102934180(RDX)

CCAY:

125634326(RDX)

DCC:	119860324(RDX)

CPIC:

101946164(RDX)

TST:	117871140(RDX)

CABI:

116822796(RDX)

MRV:	120390470(RDX)

ACS:	100559455(rdx)

ASAO:

132772167(RDX)

PVT:	110085228(RDX)

SUND:

121925063(RDX)

PBI:	103055612(RDX)

PMUR:

107296356(RDX)

CTIG:

120311708

TSR:	106543863(RDX)

PGUT:

117661144(RDX)

APRI:

131199903(RDX)

PTEX:

113441752(RDX)

NSS:

113416953

VKO:	123029254(RDX)

PMUA:

114595695(RDX)

PRAF:

128412629(RDX)

ZVI:	118084862(RDX)

HCG:	128349961(RDX)

GJA:	107126002(RDX)

STOW:

125430745(RDX)

EMC:	129325689(RDX)

XLA:	108707573(rdx.L) 733147(rdx.S)

XTR:	447978(rdx)

NPR:	108786858(RDX)

RTEM:

120929254(RDX)

BBUF:

120996376(RDX)

BGAR:

122931101(RDX)

PWL:	138248599(RDX)

MUO:	115468508(RDX)

GSH:	117362669(RDX)

SRX:	107707084 107757412

SANH:

SGH:

CCAR:

CAUA:

CGIB:

PTET:

LROH:

OMC:

RKG:

MAMB:

CIDE:

CERY:

MASI:

IPU:

IFU:

PHYP:

113537665(rdx)

SMEO:

TFD:

TVC:

CGAR:

NGRA:

TRN:

AMEX:

CMAO:

EEE:

CHAR:

SPIL:

TRU:	101062757 101072012

TFS:

130528969

TNG:	GSTEN00027138G001 GSTEN00029180G001

LCO:	104928670 104929104

NCC:

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

ELY:	117250058 117251195

EFO:	125884750 125899795

PLEP:

121948961 121962647

SLUC:

116044822 116061819

ECRA:

117939361 117952383

ESP:	116673792 116697888

PFLV:

114551128 114563792(rdx)

GAT:

120831874

PPUG:

119213516 119228893

AFB:	129104215 129111599

CLUM:

117743669

PSWI:

130204421

CANA:

137793956 137803552

CVE:	137878890 137892093

MSAM:

119902878 119904459

SCHU:

122871845 122885990

CUD:	121506099 121522733

SPUL:

LMIX:

ALAT:

ASTR:

MZE:	101469272 101478951

ONL:	100691947 100697050

OAU:	116319183 116332569

OLA:	101156069 101156778

OML:	112155354 112160082

CSAI:

133425223 133445726

XMA:	102227279 102229357

XCO:	114138243 114147987

XHE:	116716126 116722832

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122826856 122839838

PPRL:

129361310

CVG:	107087342 107105020

CTUL:

119778334 119794900

GMU:	124861315 124871074

NFU:	107381115 107389636

KMR:	108244161 108244201

ALIM:

106529288 106530686

NWH:	119419711 119428831

AOCE:

111571685 111583876

EJA:	138201489 138207018

BFRE:

138628632 138629574

MCEP:

125001254 125017604

CSEM:

103391967

POV:	109638006 109641404 109642050 109646997

SSEN:

122759256 122762699

SSOE:

131446424 131455271

HHIP:

117754610 117776465

HSP:	118103383 118119664

PPLT:

128431217 128455891

SMAU:

118282728 118317010

LCF:	108892900 108897040

SDU:	111218761 111237542

SLAL:

111650530(ezr) 111665370

XGL:	120798205 120801913

HCQ:	109520918 109522312

SSCV:

125973900 125988576

SBIA:

133492200 133511918

PEE:	133410319 133410861

PTAO:

133487200 133489920

BPEC:

110156248 110172309

ENY:	140359321 140360960

MALB:

109955631 109970961

BSPL:

114846894 114869949

SJO:	128354138 128367725

SSCO:

133992917 134006629

GMH:	115533384 115542091

SASA:

106574536 106575324 106582091 106586613

STRU:

115155781 115161116 115179847 115196132

OTW:	112225465 112233735 112253689 112266424

OMY:	110495768 110501655 110520426 110527401

OGO:	124007868 124010844 124044115 124045926

ONE:	115112370 115128525 115129782 115132613

OKI:	109869461 109871094 109879436 109890579

OKE:	118363840 118366807 118370280 118386231

OMM:	135519148 135542632 135543449 135547452

OCLA:

139373148 139380704 139403152 139412975

SALP:

111953175 111959849 112067739

SNH:	120033099 120051329 120058431 120064090

CCLU:

121536868 121559441 121571672

ELS:	105016448 105019886

OEP:	134007435 134017734

SFM:

PKI:

AANG:

AROT:

CCOG:

LOC:	102682335(rdx)

PSPA:

121320460 121327948

ARUT:

117405840 117407280

PSEX:

120523026

LCM:	102360693(RDX)

CMK:	103178606(msna) 103186512

RTP:	109912402 109932054

CPLA:

122550719 122557289(msna)

HOC:	132816457 132820413(msna)

LERI:

129698120 129702061(msna)

PMRN:

116956536

BFO:

118422870

BBEL:

109469904

CIN:	445597(erm)

SCLV:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:	100376717(MSN)

PFLL:

PVUL:

LSAX:

HASI:

HCRA:

MAEA:

LJP:

LLON:

ATEN:

MCAZ:

MFOO:

HSY:	130644525 130644527

RES:

135685510

SRE:	PTSG_04779

» show all

Reference

PMID:17226784

Authors

Khan SY, Ahmed ZM, Shabbir MI, Kitajiri S, Kalsoom S, Tasneem S, Shayiq S, Ramesh A, Srisailpathy S, Khan SN, Smith RJ, Riazuddin S, Friedman TB, Riazuddin S

Title

Mutations of the RDX gene cause nonsyndromic hearing loss at the DFNB24 locus.

Journal

Hum Mutat 28:417-23 (2007)
DOI:10.1002/humu.20469

Reference

PMID:8486357

Authors

Wilgenbus KK, Milatovich A, Francke U, Furthmayr H

Title

Molecular cloning, cDNA sequence, and chromosomal assignment of the human radixin gene and two dispersed pseudogenes.

Journal

Genomics 16:199-206 (1993)
DOI:10.1006/geno.1993.1159

Sequence

[hsa:5962]

LinkDB

DBGET integrated database retrieval system