| Entry |
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| Name |
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
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| Definition |
K00512 K00070 K12343 (K13369,K00089,K00037) (K04119,K10207)
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| Diagram |
| M00977 | C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone |
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| Class |
Pathway modules; Lipid metabolism; Sterol biosynthesis
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| Pathway |
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| Orthology |
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| Complete |
| ptr | Pan troglodytes (chimpanzee) |
| pps | Pan paniscus (bonobo) |
| ggo | Gorilla gorilla gorilla (western lowland gorilla) |
| pon | Pongo abelii (Sumatran orangutan) |
| ppyg | Pongo pygmaeus (Bornean orangutan) |
| nle | Nomascus leucogenys (northern white-cheeked gibbon) |
| hmh | Hylobates moloch (silvery gibbon) |
| ssyn | Symphalangus syndactylus (siamang) |
| mcc | Macaca mulatta (rhesus monkey) |
| mcf | Macaca fascicularis (crab-eating macaque) |
| mthb | Macaca thibetana thibetana (Pere David's macaque) |
| mni | Macaca nemestrina (pig-tailed macaque) |
| csab | Chlorocebus sabaeus (green monkey) |
| caty | Cercocebus atys (sooty mangabey) |
| panu | Papio anubis (olive baboon) |
| tge | Theropithecus gelada (gelada) |
| mleu | Mandrillus leucophaeus (drill) |
| rro | Rhinopithecus roxellana (golden snub-nosed monkey) |
| rbb | Rhinopithecus bieti (black snub-nosed monkey) |
| tfn | Trachypithecus francoisi (Francois's langur) |
| pteh | Piliocolobus tephrosceles (Ugandan red Colobus) |
| cang | Colobus angolensis palliatus (Angola colobus) |
| cjc | Callithrix jacchus (white-tufted-ear marmoset) |
| sbq | Saimiri boliviensis boliviensis (Bolivian squirrel monkey) |
| cimi | Cebus imitator (Panamanian white-faced capuchin) |
| anan | Aotus nancymaae (Ma's night monkey) |
| csyr | Carlito syrichta (Philippine tarsier) |
| mmur | Microcebus murinus (gray mouse lemur) |
| lcat | Lemur catta (Ring-tailed lemur) |
| eruf | Eulemur rufifrons (Bennett's brown lemur) |
| pcoq | Propithecus coquereli (Coquerel's sifaka) |
| oga | Otolemur garnettii (small-eared galago) |
| mmu | Mus musculus (house mouse) |
| mcal | Mus caroli (Ryukyu mouse) |
| mpah | Mus pahari (shrew mouse) |
| rno | Rattus norvegicus (rat) |
| mcoc | Mastomys coucha (southern multimammate mouse) |
| anu | Arvicanthis niloticus (African grass rat) |
| asyl | Apodemus sylvaticus (European woodmouse) |
| mmiu | Micromys minutus (European harvest mouse) |
| cge | Cricetulus griseus (Chinese hamster) |
| prob | Phodopus roborovskii (desert hamster) |
| pleu | Peromyscus leucopus (white-footed mouse) |
| pmav | Peromyscus maniculatus bairdii (prairie deer mouse) |
| morg | Microtus oregoni (creeping vole) |
| mfot | Alexandromys fortis (reed vole) |
| aamp | Arvicola amphibius (Eurasian water vole) |
| ngi | Nannospalax galili (Upper Galilee mountains blind mole rat) |
| hgl | Heterocephalus glaber (naked mole-rat) |
| cpoc | Cavia porcellus (domestic guinea pig) |
| ccan | Castor canadensis (American beaver) |
| dord | Dipodomys ordii (Ord's kangaroo rat) |
| dsp | Dipodomys spectabilis (banner-tailed kangaroo rat) |
| dmer | Dipodomys merriami (Merriam's kangaroo rat) |
| plop | Perognathus longimembris pacificus (Pacific pocket mouse) |
| mmma | Marmota marmota marmota (Alpine marmot) |
| tup | Tupaia belangeri chinensis (Chinese tree shrew) |
| gvr | Galeopterus variegatus (Sunda flying lemur) |
| cfa | Canis lupus familiaris (dog) |
| clud | Canis lupus dingo (dingo) |
| vvp | Vulpes vulpes (red fox) |
| vlg | Vulpes lagopus (Arctic fox) |
| npo | Nyctereutes procyonoides (raccoon dog) |
| aml | Ailuropoda melanoleuca (giant panda) |
| umr | Ursus maritimus (polar bear) |
| uah | Ursus arctos (brown bear) |
| uar | Ursus americanus (American black bear) |
| elk | Enhydra lutris kenyoni (northern sea otter) |
| llv | Lutra lutra (Eurasian river otter) |
| mpuf | Mustela putorius furo (domestic ferret) |
| mnp | Mustela nigripes (black-footed ferret) |
| mlk | Mustela lutreola (European mink) |
| nvs | Neogale vison (American mink) |
| mmaq | Martes martes (European pine marten) |
| oro | Odobenus rosmarus divergens (Pacific walrus) |
| eju | Eumetopias jubatus (Steller sea lion) |
| zca | Zalophus californianus (California sea lion) |
| mlx | Mirounga leonina (Southern elephant seal) |
| mano | Mirounga angustirostris (Northern elephant seal) |
| lww | Leptonychotes weddellii (Weddell seal) |
| fca | Felis catus (domestic cat) |
| pyu | Herpailurus yagouaroundi (jaguarundi) |
| pcoo | Puma concolor (puma) |
| pbg | Prionailurus bengalensis (leopard cat) |
| pviv | Prionailurus viverrinus (fishing cat) |
| lgf | Leopardus geoffroyi (Geoffroy's cat) |
| aju | Acinonyx jubatus (cheetah) |
| ptg | Panthera tigris altaica (Amur tiger) |
| ppad | Panthera pardus (leopard) |
| puc | Panthera uncia (snow leopard) |
| hhv | Hyaena hyaena (striped hyena) |
| ccru | Crocuta crocuta (spotted hyena) |
| biu | Bos indicus (zebu cattle) |
| bjv | Bos javanicus (banteng) |
| bbub | Bubalus bubalis (water buffalo) |
| bke | Bubalus kerabau (carabao) |
| bbis | Bison bison bison (American bison) |
| ocan | Ovis canadensis (bighorn sheep) |
| btax | Budorcas taxicolor (takin) |
| csum | Capricornis sumatraensis (Sumatran serow) |
| oda | Oryx dammah (scimitar-horned oryx) |
| ccad | Cervus canadensis (wapiti) |
| mree | Muntiacus reevesi (Reeves' muntjac) |
| ovr | Odocoileus virginianus (white-tailed deer) |
| mbez | Moschus berezovskii (Chinese forest musk deer) |
| cfr | Camelus ferus (Wild Bactrian camel) |
| cbai | Camelus bactrianus (Bactrian camel) |
| cdk | Camelus dromedarius (Arabian camel) |
| vpc | Vicugna pacos (alpaca) |
| bacu | Balaenoptera acutorostrata scammoni (minke whale) |
| bmus | Balaenoptera musculus (blue whale) |
| lve | Lipotes vexillifer (Yangtze River dolphin) |
| oor | Orcinus orca (killer whale) |
| lalb | Lagenorhynchus albirostris (white-beaked dolphin) |
| gmf | Globicephala melas (long-finned pilot whale) |
| ddp | Delphinus delphis (saddleback dolphin) |
| scoo | Stenella coeruleoalba (striped dolphin) |
| pcrs | Pseudorca crassidens (false killer whale) |
| dle | Delphinapterus leucas (beluga whale) |
| pcad | Physeter macrocephalus (sperm whale) |
| psiu | Phocoena sinus (vaquita) |
| pphc | Phocoena phocoena (harbor porpoise) |
| nasi | Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise) |
| hamp | Hyperoodon ampullatus (northern bottlenose whale) |
| ecb | Equus caballus (horse) |
| epz | Equus przewalskii (Przewalski's horse) |
| mmf | Molossus molossus (Pallas's mastiff bat) |
| rfq | Rhinolophus ferrumequinum (greater horseshoe bat) |
| pale | Pteropus alecto (black flying fox) |
| pgig | Pteropus vampyrus (Indian flying fox) |
| pvp | Pteropus vampyrus (large flying fox) |
| ray | Rousettus aegyptiacus (Egyptian rousette) |
| mjv | Manis javanica (Malayan pangolin) |
| lav | Loxodonta africana (African savanna elephant) |
| tmu | Trichechus manatus latirostris (Florida manatee) |
| shr | Sarcophilus harrisii (Tasmanian devil) |
| afz | Antechinus flavipes (yellow-footed antechinus) |
| pcw | Phascolarctos cinereus (koala) |
| tvp | Trichosurus vulpecula (common brushtail) |
| pbrv | Petaurus breviceps papuanus (sugar glider) |
| npd | Nothoprocta perdicaria (Chilean tinamou) |
| dne | Dromaius novaehollandiae (emu) |
| asn | Alligator sinensis (Chinese alligator) |
| amj | Alligator mississippiensis (American alligator) |
| cpoo | Crocodylus porosus (Australian saltwater crocodile) |
| pss | Pelodiscus sinensis (Chinese soft-shelled turtle) |
| ciz | Carettochelys insculpta (pitted-shelled turtle) |
| cmy | Chelonia mydas (green sea turtle) |
| ccay | Caretta caretta (Loggerhead turtle) |
| lkp | Lepidochelys kempii (Atlantic ridley) |
| nds | Natator depressus (flatback sea turtle) |
| dcc | Dermochelys coriacea (leatherback sea turtle) |
| cpic | Chrysemys picta (western painted turtle) |
| tst | Trachemys scripta elegans (red-eared slider) |
| cabi | Chelonoidis abingdonii (Abingdon island giant tortoise) |
| mrv | Mauremys reevesii (Reeves's turtle) |
| emq | Emydura macquarii macquarii (eastern short-necked turtle) |
| acs | Anolis carolinensis (green anole) |
| asao | Anolis sagrei ordinatus (Brown anole) |
| pvt | Pogona vitticeps (central bearded dragon) |
| sund | Sceloporus undulatus (fence lizard) |
| pbi | Python bivittatus (Burmese python) |
| pmur | Protobothrops mucrosquamatus (Taiwan habu) |
| ctig | Crotalus tigris (Tiger rattlesnake) |
| tsr | Thamnophis sirtalis (common garter snake) |
| pgut | Pantherophis guttatus (corn snake) |
| pcae | Pituophis catenifer annectens (San Diego gophersnake) |
| apri | Ahaetulla prasina (Asian vine snake) |
| nss | Notechis scutatus (mainland tiger snake) |
| pmua | Podarcis muralis (common wall lizard) |
| praf | Podarcis raffonei (Aeolian wall lizard) |
| hcg | Hemicordylus capensis (graceful crag lizard) |
| gja | Gekko japonicus (Schlegel's Japanese gecko) |
| stow | Sphaerodactylus townsendi (Townsend's least gecko) |
| emc | Eublepharis macularius (Leopard gecko) |
| xla | Xenopus laevis (African clawed frog) |
| xtr | Xenopus tropicalis (tropical clawed frog) |
| npr | Nanorana parkeri (Xizang Plateau frog) |
| rtem | Rana temporaria (common frog) |
| acat | Aquarana catesbeiana (American bullfrog) |
| pads | Pyxicephalus adspersus (African bullfrog) |
| bbuf | Bufo bufo (common toad) |
| pwl | Pleurodeles waltl (Iberian ribbed newt) |
| pmax | Pecten maximus (king scallop) |
| airr | Argopecten irradians (bay scallop) |
| yba | Ylistrum balloti (Ballot's saucer scallop) |
| mmer | Mercenaria mercenaria (northern quahog) |
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| Reaction |
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| Compound |
| C05138 | 17alpha-Hydroxypregnenolone |
| C01176 | 17alpha-Hydroxyprogesterone |
| C22831 | 5alpha-Pregnan-17alpha-ol-3,20-dione |
| C22832 | 5alpha-Pregnane-3alpha,17alpha-diol-20-one |
| C03852 | Androstan-3alpha,17beta-diol |
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| Reference |
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| Authors |
Miller WL, Auchus RJ |
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| Title |
The "backdoor pathway" of androgen synthesis in human male sexual development. |
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| Journal |
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| LinkDB |
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