KEGG   PATHWAY: axx00230
Entry
axx00230                    Pathway                                
Name
Purine metabolism - Achromobacter xylosoxidans NCTC10807
Class
Metabolism; Nucleotide metabolism
Pathway map
axx00230  Purine metabolism
axx00230

Module
axx_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:axx00230]
axx_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:axx00230]
axx_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:axx00230]
axx_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:axx00230]
axx_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:axx00230]
Other DBs
GO: 0006163 0042278
Organism
Achromobacter xylosoxidans NCTC10807 [GN:axx]
Gene
ERS451415_00139  cpdA_1; 3'%2C5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
ERS451415_00224  cpdA_2; 3'%2C5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
ERS451415_00287  [KO:K11751] [EC:3.1.3.5 3.6.1.45]
ERS451415_00619  apaH_1; Bis(5'-nucleosyl)-tetraphosphatase%2C symmetrical [KO:K01525] [EC:3.6.1.41]
ERS451415_00638  adoK; Adenosine kinase [KO:K00856] [EC:2.7.1.20]
ERS451415_00647  nrdB; Ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
ERS451415_00648  nrdA; Ribonucleoside-diphosphate reductase 1 subunit alpha [KO:K00525] [EC:1.17.4.1]
ERS451415_00910  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
ERS451415_01011  purH; Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
ERS451415_01328  apaH_2; Bis(5'-nucleosyl)-tetraphosphatase [symmetrical] [KO:K01525] [EC:3.6.1.41]
ERS451415_01432  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
ERS451415_01541  [KO:K16842] [EC:3.5.2.5]
ERS451415_01561  yfiH; Laccase domain protein yfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
ERS451415_01636  cysD_1; Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
ERS451415_01637  cysNC_1; Bifunctional enzyme CysN/CysC [KO:K00956] [EC:2.7.7.4]
ERS451415_01798  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
ERS451415_01921  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
ERS451415_01976  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
ERS451415_01990  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
ERS451415_02474  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
ERS451415_02500  guaA_1; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
ERS451415_02622  surE; 5'-nucleotidase surE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
ERS451415_02678  spoT; Bifunctional (p)ppGpp synthase/hydrolase SpoT [KO:K01139] [EC:2.7.6.5 3.1.7.2]
ERS451415_02680  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
ERS451415_02689  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
ERS451415_02697  [KO:K01519] [EC:3.6.1.66]
ERS451415_02943  guaA_2; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
ERS451415_03078  nrdD; Anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
ERS451415_03158  prs_1; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ERS451415_03455  guaA_3; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
ERS451415_03456  guaB; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
ERS451415_03541  [KO:K22879] [EC:1.14.13.113]
ERS451415_03625  purL; Phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
ERS451415_03701  cpdB; 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
ERS451415_03878  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
ERS451415_03934  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
ERS451415_03984  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
ERS451415_04036  [KO:K21053] [EC:3.5.4.2]
ERS451415_04186  [KO:K01951] [EC:6.3.5.2]
ERS451415_04352  algC_1; Phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
ERS451415_04824  ppx; Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ERS451415_04905  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
ERS451415_04906  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
ERS451415_04909  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
ERS451415_05363  prs_2; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ERS451415_05389  algC_2; Phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
ERS451415_05476  lhyD; L-hydantoinase [KO:K01466] [EC:3.5.2.5]
ERS451415_05584  allA; Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
ERS451415_05613  [KO:K01081] [EC:3.1.3.5]
ERS451415_05881  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
ERS451415_05888  purT; Phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
ERS451415_06043  cysNC_2; Bifunctional enzyme CysN/CysC [KO:K00955] [EC:2.7.7.4 2.7.1.25]
ERS451415_06044  cysD_2; Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
ERS451415_06092  dgt; Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
axx00030  Pentose phosphate pathway
axx00220  Arginine biosynthesis
axx00250  Alanine, aspartate and glutamate metabolism
axx00260  Glycine, serine and threonine metabolism
axx00340  Histidine metabolism
axx00630  Glyoxylate and dicarboxylate metabolism
axx00730  Thiamine metabolism
axx00740  Riboflavin metabolism
axx00790  Folate biosynthesis
KO pathway
ko00230   

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