KEGG   PATHWAY: bta00330
Entry
bta00330                    Pathway                                
Name
Arginine and proline metabolism - Bos taurus (cow)
Class
Metabolism; Amino acid metabolism
Pathway map
bta00330  Arginine and proline metabolism
bta00330

Module
bta_M00015  Proline biosynthesis, glutamate => proline [PATH:bta00330]
bta_M00047  Creatine pathway [PATH:bta00330]
bta_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:bta00330]
bta_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:bta00330]
bta_M00970  Proline degradation, proline => glutamate [PATH:bta00330]
bta_M00972  Proline metabolism [PATH:bta00330]
Other DBs
GO: 0006525 0006560
Organism
Bos taurus (cow) [GN:bta]
Gene
100126042  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor [KO:K00294] [EC:1.2.1.88]
280997  AMD1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
281206  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
281293  MAOA; amine oxidase [flavin-containing] A [KO:K00274] [EC:1.4.3.4]
281365  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
281618  ALDH1B1; LOW QUALITY PROTEIN: aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
281692  CKMT1A; creatine kinase U-type, mitochondrial precursor [KO:K00933] [EC:2.7.3.2]
282876  NOS2; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
286822  CKM; creatine kinase M-type [KO:K27382]
286886  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
287024  NOS3; nitric oxide synthase, endothelial [KO:K13242] [EC:1.14.13.39]
338445  MAOB; amine oxidase [flavin-containing] B [KO:K00274] [EC:1.4.3.4]
359722  SAT2; thialysine N-epsilon-acetyltransferase [KO:K00657] [EC:2.3.1.57]
414348  P4HA3; prolyl 4-hydroxylase subunit alpha-3 precursor [KO:K00472] [EC:1.14.11.2]
414732  GATM; glycine amidinotransferase, mitochondrial precursor [KO:K00613] [EC:2.1.4.1]
504987  PYCR2; pyrroline-5-carboxylate reductase 2 [KO:K00286] [EC:1.5.1.2]
505094  PRODH; proline dehydrogenase 1, mitochondrial [KO:K00318] [EC:1.5.5.2]
505323  OAT; ornithine aminotransferase, mitochondrial precursor [KO:K00819] [EC:2.6.1.13]
505916  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
506001  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial precursor [KO:K18123] [EC:4.1.3.16]
506961  AZIN2; antizyme inhibitor 2 [KO:K01583] [EC:4.1.1.19]
507327  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform 2 precursor [KO:K00472] [EC:1.14.11.2]
507477  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
507913  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
508542  PRODH2; hydroxyproline dehydrogenase [KO:K11394] [EC:1.5.5.3]
508629  ALDH2; aldehyde dehydrogenase, mitochondrial precursor [KO:K00128] [EC:1.2.1.3]
508861  SAT1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
509751  AOC1; amiloride-sensitive amine oxidase precursor [KO:K11182] [EC:1.4.3.22]
510525  L3HYPDH; trans-L-3-hydroxyproline dehydratase [KO:K18384] [EC:4.2.1.77]
512526  PYCR3; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
512626  CNDP2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
513608  ARG1; arginase-1 [KO:K01476] [EC:3.5.3.1]
513967  ALDH3A2; aldehyde dehydrogenase family 3 member A2 [KO:K00128] [EC:1.2.1.3]
514509  AGMAT; guanidino acid hydrolase, mitochondrial isoform X2 [KO:K27001]
514759  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase [KO:K12657] [EC:2.7.2.11 1.2.1.41]
515270  GAMT; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
515547  [KO:K01581] [EC:4.1.1.17]
516210  CKB; creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
518288  P4HA1; prolyl 4-hydroxylase subunit alpha-1 precursor [KO:K00472] [EC:1.14.11.2]
518752  ARG2; arginase-2, mitochondrial precursor [KO:K01476] [EC:3.5.3.1]
527211  SMOX; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
534520  [KO:K00802] [EC:2.5.1.22]
536132  NOS1; nitric oxide synthase 1 isoform X1 [KO:K13240] [EC:1.14.13.39]
537539  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
538944  CKMT2; creatine kinase S-type, mitochondrial precursor [KO:K00933] [EC:2.7.3.2]
539606  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial [KO:K00286] [EC:1.5.1.2]
614200  CNDP1; beta-Ala-His dipeptidase precursor [KO:K05604] [EC:3.4.13.20]
615334  DAO; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
615950  SMS; spermine synthase [KO:K00802] [EC:2.5.1.22]
781648  LAP3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
783525  CARNS1; carnosine synthase 1 isoform X2 [KO:K14755] [EC:6.3.2.11]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
bta00020  Citrate cycle (TCA cycle)
bta00220  Arginine biosynthesis
bta00250  Alanine, aspartate and glutamate metabolism
bta00260  Glycine, serine and threonine metabolism
bta00270  Cysteine and methionine metabolism
bta00310  Lysine degradation
bta00410  beta-Alanine metabolism
bta00470  D-Amino acid metabolism
bta00480  Glutathione metabolism
bta00630  Glyoxylate and dicarboxylate metabolism
bta00650  Butanoate metabolism
bta00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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