KEGG   PATHWAY: bta00620
Entry
bta00620                    Pathway                                
Name
Pyruvate metabolism - Bos taurus (cow)
Class
Metabolism; Carbohydrate metabolism
Pathway map
bta00620  Pyruvate metabolism
bta00620

Module
bta_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:bta00620]
Other DBs
GO: 0006090
Organism
Bos taurus (cow) [GN:bta]
Gene
101905254  [KO:K01759] [EC:4.4.1.5]
281274  LDHA; L-lactate dehydrogenase A chain [KO:K00016] [EC:1.1.1.27]
281275  LDHB; L-lactate dehydrogenase B chain isoform LDHB [KO:K00016] [EC:1.1.1.27]
281306  MDH2; malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
281590  ACACA; acetyl-CoA carboxylase 1 [KO:K11262] [EC:6.4.1.2 6.3.4.14 2.1.3.15]
281618  ALDH1B1; LOW QUALITY PROTEIN: aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
282855  PCK1; phosphoenolpyruvate carboxykinase, cytosolic [GTP] [KO:K01596] [EC:4.1.1.32]
282856  PCK2; phosphoenolpyruvate carboxykinase [GTP], mitochondrial [KO:K01596] [EC:4.1.1.32]
282873  ACSS1; acetyl-coenzyme A synthetase 2-like, mitochondrial [KO:K01895] [EC:6.2.1.1]
338471  PC; pyruvate carboxylase, mitochondrial precursor [KO:K01958] [EC:6.4.1.1]
407109  PDHA1; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial precursor [KO:K00161] [EC:1.2.4.1]
504764  GRHPR; glyoxylate reductase/hydroxypyruvate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
505515  ADH5; alcohol dehydrogenase class-3 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
506459  ACSS2; acetyl-coenzyme A synthetase, cytoplasmic [KO:K01895] [EC:6.2.1.1]
507477  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
507817  ME2; NAD-dependent malic enzyme, mitochondrial [KO:K00027] [EC:1.1.1.38]
507844  ACYP1; acylphosphatase-1 [KO:K01512] [EC:3.6.1.7]
508629  ALDH2; aldehyde dehydrogenase, mitochondrial precursor [KO:K00128] [EC:1.2.1.3]
509274  HAGH; hydroxyacylglutathione hydrolase, mitochondrial [KO:K01069] [EC:3.1.2.6]
509519  LDHAL6B; L-lactate dehydrogenase A-like 6B [KO:K00016] [EC:1.1.1.27]
509744  ADH1C; alcohol dehydrogenase 1C [KO:K13951] [EC:1.1.1.1]
510284  LDHD; probable D-lactate dehydrogenase, mitochondrial [KO:K00102] [EC:1.1.2.4]
510551  ADH6; alcohol dehydrogenase 6 [KO:K13952] [EC:1.1.1.1]
511082  ACAT1; acetyl-CoA acetyltransferase, mitochondrial precursor [KO:K00626] [EC:2.3.1.9]
512044  ACAT2; acetyl-CoA acetyltransferase, cytosolic [KO:K00626] [EC:2.3.1.9]
512571  PKM; pyruvate kinase PKM [KO:K00873] [EC:2.7.1.40]
512723  DLAT; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [KO:K00627] [EC:2.3.1.12]
513967  ALDH3A2; aldehyde dehydrogenase family 3 member A2 [KO:K00128] [EC:1.2.1.3]
515338  ACACB; acetyl-CoA carboxylase 2 [KO:K01946] [EC:6.4.1.2 6.3.4.14 2.1.3.15]
520260  FH; fumarate hydratase, mitochondrial [KO:K01679] [EC:4.2.1.2]
520508  ADH4; all-trans-retinol dehydrogenase [NAD(+)] ADH4 [KO:K13980] [EC:1.1.1.1]
525155  ACOT12; acetyl-coenzyme A thioesterase [KO:K01067] [EC:3.1.2.1]
525813  ME3; NADP-dependent malic enzyme, mitochondrial [KO:K00029] [EC:1.1.1.40]
533910  DLD; dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
534808  ADH7; LOW QUALITY PROTEIN: all-trans-retinol dehydrogenase [NAD(+)] ADH7 [KO:K13951] [EC:1.1.1.1]
535182  MDH1; malate dehydrogenase, cytoplasmic isoform MDH1 [KO:K00025] [EC:1.1.1.37]
537256  LDHC; L-lactate dehydrogenase C chain isoform 2 [KO:K00016] [EC:1.1.1.27]
537539  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
539579  PKLR; pyruvate kinase PKLR [KO:K12406] [EC:2.7.1.40]
540335  GLO1; lactoylglutathione lyase [KO:K01759] [EC:4.4.1.5]
540985  ME1; NADP-dependent malic enzyme [KO:K00029] [EC:1.1.1.40]
613610  PDHB; pyruvate dehydrogenase E1 component subunit beta, mitochondrial precursor [KO:K00162] [EC:1.2.4.1]
618607  AKR1A1; aldo-keto reductase family 1 member A1 [KO:K00002] [EC:1.1.1.2]
767889  ACYP2; acylphosphatase-2 [KO:K01512] [EC:3.6.1.7]
768012  PDHA2; pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial [KO:K00161] [EC:1.2.4.1]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
bta00010  Glycolysis / Gluconeogenesis
bta00020  Citrate cycle (TCA cycle)
bta00061  Fatty acid biosynthesis
bta00250  Alanine, aspartate and glutamate metabolism
bta00260  Glycine, serine and threonine metabolism
bta00290  Valine, leucine and isoleucine biosynthesis
bta00630  Glyoxylate and dicarboxylate metabolism
bta00640  Propanoate metabolism
bta00650  Butanoate metabolism
bta00760  Nicotinate and nicotinamide metabolism
KO pathway
ko00620   

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