KEGG   PATHWAY: bui00230
Entry
bui00230                    Pathway                                
Name
Purine metabolism - Burkholderia sp. PAMC 28687
Class
Metabolism; Nucleotide metabolism
Pathway map
bui00230  Purine metabolism
bui00230

Module
bui_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bui00230]
bui_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bui00230]
bui_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bui00230]
bui_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bui00230]
bui_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bui00230]
bui_M00546  Purine degradation, xanthine => urea [PATH:bui00230]
bui_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bui00230]
bui_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bui00230]
Other DBs
GO: 0006163 0042278
Organism
Burkholderia sp. PAMC 28687 [GN:bui]
Gene
AX768_09965  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
AX768_11540  phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
AX768_00720  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
AX768_23005  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
AX768_04775  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
AX768_02975  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
AX768_04575  phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
AX768_06915  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
AX768_01585  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
AX768_02610  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
AX768_02605  N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
AX768_02600  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
AX768_01765  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
AX768_01195  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
AX768_00815  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
AX768_00945  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
AX768_08680  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
AX768_08165  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
AX768_17185  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
AX768_08015  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
AX768_21595  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
AX768_12955  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
AX768_05865  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
AX768_08130  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
AX768_03760  non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
AX768_19905  FAD-binding molybdopterin dehydrogenase [KO:K13481] [EC:1.17.1.4]
AX768_03930  FAD-binding molybdopterin dehydrogenase [KO:K13481] [EC:1.17.1.4]
AX768_19910  aldehyde oxidase [KO:K13482] [EC:1.17.1.4]
AX768_03925  aldehyde oxidase [KO:K13482] [EC:1.17.1.4]
AX768_17475  dehydrogenase [KO:K11177] [EC:1.17.1.4]
AX768_28065  acylaldehyde oxidase [KO:K11177] [EC:1.17.1.4]
AX768_17470  molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
AX768_28060  FAD-binding molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
AX768_28055  (2Fe-2S)-binding protein [KO:K13483]
AX768_05875  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
AX768_23320  guanine deaminase [KO:K01487] [EC:3.5.4.3]
AX768_03905  guanine deaminase [KO:K01487] [EC:3.5.4.3]
AX768_03775  guanylate kinase [KO:K00942] [EC:2.7.4.8]
AX768_27115  ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
AX768_12930  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
AX768_12915  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
AX768_14015  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
AX768_03785  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
AX768_10485  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
AX768_09375  GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
AX768_08060  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
AX768_12900  sugar kinase [KO:K00856] [EC:2.7.1.20]
AX768_23200  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
AX768_03915  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
AX768_12405  adenylate kinase [KO:K00939] [EC:2.7.4.3]
AX768_17135  metallophosphatase [KO:K03651] [EC:3.1.4.53]
AX768_25900  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
AX768_26435  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
AX768_12155  bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [KO:K01525] [EC:3.6.1.41]
AX768_25990  adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
AX768_03205  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
AX768_03200  sulfate adenylyltransferase small subunit [KO:K00957] [EC:2.7.7.4]
AX768_15775  FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
AX768_06045  5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
AX768_06025  OHCU decarboxylase [KO:K13485] [EC:4.1.1.97]
AX768_06015  Asp/Glu racemase [KO:K16841] [EC:5.1.99.3]
AX768_06020  allantoinase [KO:K16842] [EC:3.5.2.5]
AX768_06030  allantoicase [KO:K01477] [EC:3.5.3.4]
AX768_06035  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
AX768_29330  ureidoglycolate lyase [KO:K16856] [EC:4.3.2.3]
AX768_11500  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
AX768_11495  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
AX768_11490  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
AX768_20240  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bui00030  Pentose phosphate pathway
bui00220  Arginine biosynthesis
bui00250  Alanine, aspartate and glutamate metabolism
bui00260  Glycine, serine and threonine metabolism
bui00340  Histidine metabolism
bui00630  Glyoxylate and dicarboxylate metabolism
bui00730  Thiamine metabolism
bui00740  Riboflavin metabolism
bui00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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