KEGG   PATHWAY: bxb00620
Entry
bxb00620                    Pathway                                
Name
Pyruvate metabolism - Paraburkholderia xenovorans LB400
Class
Metabolism; Carbohydrate metabolism
Pathway map
bxb00620  Pyruvate metabolism
bxb00620

Module
bxb_M00168  CAM (Crassulacean acid metabolism), dark [PATH:bxb00620]
bxb_M00169  CAM (Crassulacean acid metabolism), light [PATH:bxb00620]
bxb_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:bxb00620]
bxb_M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:bxb00620]
Other DBs
GO: 0006090
Organism
Paraburkholderia xenovorans LB400 [GN:bxb]
Gene
DR64_3558  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DR64_4024  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DR64_6404  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DR64_452  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DR64_802  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DR64_1272  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DR64_2145  aceE; pyruvate dehydrogenase (acetyl-transferring), homodimeric type [KO:K00163] [EC:1.2.4.1]
DR64_3702  aceE; pyruvate dehydrogenase (acetyl-transferring), homodimeric type [KO:K00163] [EC:1.2.4.1]
DR64_8738  aceE; pyruvate dehydrogenase (acetyl-transferring), homodimeric type [KO:K00163] [EC:1.2.4.1]
DR64_3703  aceF; dihydrolipoyllysine-residue acetyltransferase [KO:K00627] [EC:2.3.1.12]
DR64_5655  acoC; dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system [KO:K00627] [EC:2.3.1.12]
DR64_7593  e3 binding domain protein [KO:K00627] [EC:2.3.1.12]
DR64_3704  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DR64_5912  lpd3; dihydrolipoyl dehydrogenase 3 [KO:K00382] [EC:1.8.1.4]
DR64_492  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DR64_7594  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DR64_4658  acetaldehyde dehydrogenase [KO:K04073] [EC:1.2.1.10]
DR64_1246  acetaldehyde dehydrogenase [KO:K04073] [EC:1.2.1.10]
DR64_3310  acetaldehyde dehydrogenase [KO:K04073] [EC:1.2.1.10]
DR64_8617  acetaldehyde dehydrogenase [KO:K18366] [EC:1.2.1.10 1.2.1.87]
DR64_4005  zinc-binding alcohol dehydrogenase family protein [KO:K13953] [EC:1.1.1.1]
DR64_4034  zinc-binding dehydrogenase family protein [KO:K13953] [EC:1.1.1.1]
DR64_7920  zinc-binding dehydrogenase family protein [KO:K13953] [EC:1.1.1.1]
DR64_2881  S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
DR64_7059  zinc-binding dehydrogenase family protein [KO:K13979] [EC:1.1.1.2]
DR64_5647  PQQ-dependent dehydrogenase, methanol/ethanol family protein [KO:K00114] [EC:1.1.2.8]
DR64_4744  PQQ-dependent dehydrogenase, methanol/ethanol family protein [KO:K00114] [EC:1.1.2.8]
DR64_6997  cytochrome c family protein [KO:K22474] [EC:1.1.5.5]
DR64_6653  ackA; acetate kinase [KO:K00925] [EC:2.7.2.1]
DR64_5696  ackA; acetate kinase [KO:K00925] [EC:2.7.2.1]
DR64_8373  ackA; acetate kinase [KO:K00925] [EC:2.7.2.1]
DR64_6021  pta; phosphate acetyltransferase [KO:K00625] [EC:2.3.1.8]
DR64_5697  phosphate acetyl/butaryl transferase family protein [KO:K00625] [EC:2.3.1.8]
DR64_8372  phosphate acetyl/butaryl transferase family protein [KO:K00625] [EC:2.3.1.8]
DR64_2858  pyk; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
DR64_3786  accA; acetyl-CoA carboxylase, carboxyl transferase, alpha subunit [KO:K01962] [EC:6.4.1.2 2.1.3.15]
DR64_2707  accB; acetyl-CoA carboxylase, biotin carboxyl carrier protein [KO:K02160]
DR64_2706  accC; acetyl-CoA carboxylase, biotin carboxylase subunit [KO:K01961] [EC:6.4.1.2 6.3.4.14]
DR64_5208  accD; acetyl-CoA carboxylase, carboxyl transferase, beta subunit [KO:K01963] [EC:6.4.1.2 2.1.3.15]
DR64_5387  acyP; acylphosphatase [KO:K01512] [EC:3.6.1.7]
DR64_6296  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_4591  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_1101  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_1296  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_6799  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_6705  acyl-CoA reductase family protein [KO:K00128] [EC:1.2.1.3]
DR64_5051  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_8539  acyl-CoA reductase family protein [KO:K00128] [EC:1.2.1.3]
DR64_7727  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_4103  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_4478  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
DR64_5646  acoD; acetaldehyde dehydrogenase 2 [KO:K00138] [EC:1.2.1.-]
DR64_2116  acoD; acetaldehyde dehydrogenase 2 [KO:K00138] [EC:1.2.1.-]
DR64_5733  succinate CoA transferase family protein [KO:K18118] [EC:2.8.3.18]
DR64_5633  succinate CoA transferase family protein [KO:K18118] [EC:2.8.3.18]
DR64_7166  succinate CoA transferase family protein [KO:K18118] [EC:2.8.3.18]
DR64_6330  coA binding domain protein [KO:K24012] [EC:6.2.1.13]
DR64_122  FMN-dependent dehydrogenase family protein [KO:K00101] [EC:1.1.2.3]
DR64_1068  nitronate monooxygenase family protein [KO:K00101] [EC:1.1.2.3]
DR64_8203  FMN-dependent dehydrogenase family protein [KO:K00101] [EC:1.1.2.3]
DR64_4706  thiamine pyrophosphate enzyme, central domain protein [KO:K00156] [EC:1.2.5.1]
DR64_3997  thiamine pyrophosphate enzyme, central domain protein [KO:K00156] [EC:1.2.5.1]
DR64_8529  thiamine pyrophosphate enzyme, central domain protein [KO:K00156] [EC:1.2.5.1]
DR64_1571  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K03778] [EC:1.1.1.28]
DR64_4489  FAD binding domain protein [KO:K03777] [EC:1.1.5.12]
DR64_1653  FAD binding domain protein [KO:K00102] [EC:1.1.2.4]
DR64_3562  glyoxalase/Bleomycin resistance/Dioxygenase superfamily protein [KO:K01759] [EC:4.4.1.5]
DR64_1695  gloA; lactoylglutathione lyase [KO:K01759] [EC:4.4.1.5]
DR64_4204  glyoxalase/Bleomycin resistance/Dioxygenase superfamily protein [KO:K01759] [EC:4.4.1.5]
DR64_3411  gloB; hydroxyacylglutathione hydrolase [KO:K01069] [EC:3.1.2.6]
DR64_1992  metallo-beta-lactamase superfamily protein [KO:K01069] [EC:3.1.2.6]
DR64_1946  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DR64_6797  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DR64_7279  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DR64_7724  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
DR64_3218  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DR64_4141  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DR64_2445  malic enzyme, NAD binding domain protein [KO:K00029] [EC:1.1.1.40]
DR64_2732  malic enzyme, NAD binding domain protein [KO:K00029] [EC:1.1.1.40]
DR64_1056  malic enzyme, NAD binding domain protein [KO:K00029] [EC:1.1.1.40]
DR64_4476  oxaloacetate decarboxylase [KO:K01003] [EC:4.1.1.112]
DR64_5227  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DR64_826  hydrolyase, tartrate alpha subunit/fumarate, Fe-S type domain protein [KO:K01676] [EC:4.2.1.2]
DR64_3199  fumC; fumarate hydratase, class II [KO:K01679] [EC:4.2.1.2]
DR64_1112  phosphoenolpyruvate carboxylase family protein [KO:K01595] [EC:4.1.1.31]
DR64_2096  phosphoenolpyruvate carboxykinase family protein [KO:K01596] [EC:4.1.1.32]
DR64_4978  PEP-utilizing enzyme, mobile domain protein [KO:K01006] [EC:2.7.9.1]
DR64_3864  ppsA; phosphoenolpyruvate synthase [KO:K01007] [EC:2.7.9.2]
DR64_3812  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
DR64_4375  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
DR64_6068  thlA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
DR64_4422  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_40  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_47  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_1932  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_5716  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_446  hypothetical protein [KO:K00626] [EC:2.3.1.9]
DR64_460  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_8102  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_8152  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_7872  hypothetical protein [KO:K00626] [EC:2.3.1.9]
DR64_7534  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DR64_1298  hypothetical protein [KO:K00626] [EC:2.3.1.9]
DR64_3600  leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
DR64_928  leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
DR64_6744  nifV; homocitrate synthase [KO:K02594] [EC:2.3.3.14]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
bxb00010  Glycolysis / Gluconeogenesis
bxb00020  Citrate cycle (TCA cycle)
bxb00061  Fatty acid biosynthesis
bxb00250  Alanine, aspartate and glutamate metabolism
bxb00260  Glycine, serine and threonine metabolism
bxb00290  Valine, leucine and isoleucine biosynthesis
bxb00300  Lysine biosynthesis
bxb00630  Glyoxylate and dicarboxylate metabolism
bxb00640  Propanoate metabolism
bxb00650  Butanoate metabolism
bxb00760  Nicotinate and nicotinamide metabolism
bxb01059  Biosynthesis of enediyne antibiotics
KO pathway
ko00620   
LinkDB

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