KEGG   PATHWAY: cbr00230
Entry
cbr00230                    Pathway                                
Name
Purine metabolism - Caenorhabditis briggsae (nematode)
Class
Metabolism; Nucleotide metabolism
Pathway map
cbr00230  Purine metabolism
cbr00230

Module
cbr_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:cbr00230]
cbr_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cbr00230]
cbr_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cbr00230]
cbr_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cbr00230]
cbr_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cbr00230]
cbr_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:cbr00230]
Other DBs
GO: 0006163 0042278
Organism
Caenorhabditis briggsae (nematode) [GN:cbr]
Gene
CBG_00847  Cbr-gcy-1; Protein CBR-GCY-1 [KO:K01769] [EC:4.6.1.2]
CBG_00850  Cbr-gcy-5; Protein CBR-GCY-5 [KO:K01769] [EC:4.6.1.2]
CBG_00957  [KO:K18532] [EC:2.7.4.3]
CBG_01514  [KO:K07023] [EC:3.1.3.89]
CBG_01631  Cbr-gcy-23; Protein CBR-GCY-23 [KO:K01769] [EC:4.6.1.2]
CBG_02038  [KO:K01081] [EC:3.1.3.5]
CBG_02110  Cbr-gcy-31; Protein CBR-GCY-31 [KO:K01769] [EC:4.6.1.2]
CBG_02247  Cbr-ndk-1; Protein CBR-NDK-1 [KO:K00940] [EC:2.7.4.6]
CBG_02267  [KO:K01835] [EC:5.4.2.2]
CBG_02349  [KO:K01490] [EC:3.5.4.6]
CBG_02368  Cbr-gcy-12; Protein CBR-GCY-12 [KO:K01769] [EC:4.6.1.2]
CBG_02384  Cbr-ndx-6; Protein CBR-NDX-6 [KO:K13988] [EC:3.6.1.13]
CBG_03001  [KO:K01951] [EC:6.3.5.2]
CBG_03104  [KO:K00939] [EC:2.7.4.3]
CBG_03405  Cbr-pps-1; Protein CBR-PPS-1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
CBG_03574  [KO:K15779] [EC:5.4.2.2 5.4.2.7]
CBG_03675  [KO:K01587] [EC:4.1.1.21 6.3.2.6]
CBG_03898  Cbr-gcy-17; Protein CBR-GCY-17 [KO:K12323] [EC:4.6.1.2]
CBG_04436  [KO:K07127] [EC:3.5.2.17]
CBG_04537  Cbr-gcy-14; Protein CBR-GCY-14 [KO:K01769] [EC:4.6.1.2]
CBG_04937  [KO:K12319] [EC:4.6.1.2]
CBG_05718  [KO:K00088] [EC:1.1.1.205]
CBG_05749  [KO:K01488] [EC:3.5.4.4]
CBG_05751  [KO:K01488] [EC:3.5.4.4]
CBG_05895  [KO:K00940] [EC:2.7.4.6]
CBG_06032  [KO:K00856] [EC:2.7.1.20]
CBG_06559  [KO:K01769] [EC:4.6.1.2]
CBG_06726  Cbr-gcy-34; Protein CBR-GCY-34 [KO:K01769] [EC:4.6.1.2]
CBG_06847  Cbr-pde-2; Protein CBR-PDE-2 [KO:K18283] [EC:3.1.4.17]
CBG_07710  Cbr-gcy-36; Protein CBR-GCY-36 [KO:K12319] [EC:4.6.1.2]
CBG_08829  [KO:K01939] [EC:6.3.4.4]
CBG_10154  Cbr-rnr-1; Protein CBR-RNR-1 [KO:K10807] [EC:1.17.4.1]
CBG_10863  [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
CBG_11542  Cbr-uda-1; Protein CBR-UDA-1 [KO:K01511] [EC:3.6.1.6]
CBG_11972  Cbr-guk-1; Protein CBR-GUK-1 [KO:K00942] [EC:2.7.4.8]
CBG_12836  Cbr-pde-5; Protein CBR-PDE-5 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
CBG_13017  Cbr-pde-4; Protein CBR-PDE-4 [KO:K13293] [EC:3.1.4.53]
CBG_13085  Cbr-pdl-1; Protein CBR-PDL-1 [KO:K13758]
CBG_13501  [KO:K03783] [EC:2.4.2.1]
CBG_13634  Cbr-ndx-4; Protein CBR-NDX-4 [KO:K01518] [EC:3.6.1.17]
CBG_14198  [KO:K12304] [EC:3.6.1.6]
CBG_14784  Cbr-mig-23; Protein CBR-MIG-23 [KO:K12305] [EC:3.6.1.6]
CBG_14865  Cbr-gcy-28; Protein CBR-GCY-28 [KO:K12323] [EC:4.6.1.2]
CBG_14916  [KO:K00759] [EC:2.4.2.7]
CBG_16623  [KO:K00948] [EC:2.7.6.1]
CBG_16731  [KO:K12304] [EC:3.6.1.6]
CBG_16977  [KO:K03783] [EC:2.4.2.1]
CBG_17377  [KO:K00939] [EC:2.7.4.3]
CBG_17698  [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CBG_17711  Cbr-gcy-8; Protein CBR-GCY-8 [KO:K01769] [EC:4.6.1.2]
CBG_18000  Cbr-acy-1; Protein CBR-ACY-1 [KO:K08049] [EC:4.6.1.1]
CBG_18013  [KO:K00764] [EC:2.4.2.14]
CBG_18026  [KO:K01952] [EC:6.3.5.3]
CBG_18544  Cbr-pde-6; Protein CBR-PDE-6 [KO:K18437] [EC:3.1.4.53]
CBG_19543  Cbr-gcy-15; Protein CBR-GCY-15 [KO:K01769] [EC:4.6.1.2]
CBG_19800  [KO:K00760] [EC:2.4.2.8]
CBG_19806  [KO:K21138] [EC:3.1.7.2]
CBG_20205  Cbr-rnr-2; Protein CBR-RNR-2 [KO:K10808] [EC:1.17.4.1]
CBG_20362  Cbr-pde-1; Protein CBR-PDE-1 [KO:K13755] [EC:3.1.4.17]
CBG_20390  Cbr-gcy-35; Protein CBR-GCY-35 [KO:K12319] [EC:4.6.1.2]
CBG_21178  Cbr-hap-1; Protein CBR-HAP-1 [KO:K01519] [EC:3.6.1.66]
CBG_21240  [KO:K00939] [EC:2.7.4.3]
CBG_21624  [KO:K00106] [EC:1.17.1.4 1.17.3.2]
CBG_21917  [KO:K01756] [EC:4.3.2.2]
CBG_23350  Cbr-gcy-33; Protein CBR-GCY-33 [KO:K01769] [EC:4.6.1.2]
CBG_23625  [KO:K00364] [EC:1.7.1.7]
CBG_24374  Cbr-gcy-18; Protein CBR-GCY-18 [KO:K01769] [EC:4.6.1.2]
CBG_25458  [KO:K01769] [EC:4.6.1.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cbr00030  Pentose phosphate pathway
cbr00220  Arginine biosynthesis
cbr00250  Alanine, aspartate and glutamate metabolism
cbr00260  Glycine, serine and threonine metabolism
cbr00340  Histidine metabolism
cbr00630  Glyoxylate and dicarboxylate metabolism
cbr00730  Thiamine metabolism
cbr00740  Riboflavin metabolism
cbr00790  Folate biosynthesis
KO pathway
ko00230   

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