KEGG   PATHWAY: ccar00564
Entry
ccar00564                   Pathway                                
Name
Glycerophospholipid metabolism - Cyprinus carpio (common carp)
Class
Metabolism; Lipid metabolism
Pathway map
ccar00564  Glycerophospholipid metabolism
ccar00564

Module
ccar_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:ccar00564]
ccar_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:ccar00564]
ccar_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:ccar00564]
Other DBs
GO: 0006650
Organism
Cyprinus carpio (common carp) [GN:ccar]
Gene
109044986  [KO:K14621] [EC:3.1.1.4 3.1.1.5]
109045433  [KO:K00901] [EC:2.7.1.107]
109046088  [KO:K00995] [EC:2.7.8.5]
109046094  [KO:K00995] [EC:2.7.8.5]
109046266  [KO:K14676] [EC:3.1.1.5]
109046449  sgms2a; phosphatidylcholine:ceramide cholinephosphotransferase 2 [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
109046843  [KO:K00006] [EC:1.1.1.8]
109046863  [KO:K00901] [EC:2.7.1.107]
109047822  [KO:K00967] [EC:2.7.7.14]
109048075  dgkaa; diacylglycerol kinase, alpha a [KO:K00901] [EC:2.7.1.107]
109048390  [KO:K01115] [EC:3.1.4.4]
109048533  [KO:K00901] [EC:2.7.1.107]
109048698  [KO:K13515] [EC:2.3.1.23 2.3.1.-]
109048923  [KO:K15728] [EC:3.1.3.4]
109049365  [KO:K01115] [EC:3.1.4.4]
109049471  [KO:K01049] [EC:3.1.1.7]
109049982  [KO:K13514] [EC:2.3.1.-]
109050125  [KO:K18695] [EC:3.1.4.2]
109050185  [KO:K16342] [EC:3.1.1.4]
109050360  [KO:K01049] [EC:3.1.1.7]
109050578  pla2g15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
109050579  lcat; phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
109050607  [KO:K08730] [EC:2.7.8.29]
109050615  [KO:K08730] [EC:2.7.8.29]
109051299  [KO:K06129] [EC:3.1.1.5]
109052180  [KO:K01080] [EC:3.1.3.4]
109052696  [KO:K00994] [EC:2.7.8.2]
109052885  [KO:K13523] [EC:2.3.1.51 2.3.1.-]
109053415  [KO:K15728] [EC:3.1.3.4]
109053959  [KO:K15728] [EC:3.1.3.4]
109053972  ptdss1a; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
109053974  [KO:K08729] [EC:2.7.8.-]
109055629  [KO:K13506] [EC:2.3.1.15]
109056067  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
109056722  [KO:K13509] [EC:2.3.1.51]
109056918  [KO:K00006] [EC:1.1.1.8]
109057067  [KO:K06124] [EC:3.1.3.75]
109057551  plpp4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
109058358  [KO:K13510] [EC:2.3.1.23 2.3.1.67]
109058808  [KO:K00006] [EC:1.1.1.8]
109059017  [KO:K13644] [EC:2.7.8.1 2.7.8.2]
109059026  cept1a; choline/ethanolaminephosphotransferase 1a [KO:K13644] [EC:2.7.8.1 2.7.8.2]
109059053  [KO:K00967] [EC:2.7.7.14]
109059315  chka; choline kinase alpha isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
109059440  [KO:K19007] [EC:2.3.1.51]
109059546  pcyt1bb; LOW QUALITY PROTEIN: phosphate cytidylyltransferase 1B, choline b [KO:K00968] [EC:2.7.7.15]
109059869  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
109059870  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
109059952  lpcat4; lysophospholipid acyltransferase LPCAT4 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
109060094  [KO:K13513] [EC:2.3.1.- 2.3.1.51]
109061153  [KO:K13510] [EC:2.3.1.23 2.3.1.67]
109061341  sgms2b; phosphatidylcholine:ceramide cholinephosphotransferase 2 [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
109062009  [KO:K00968] [EC:2.7.7.15]
109062182  [KO:K13644] [EC:2.7.8.1 2.7.8.2]
109063141  [KO:K16343] [EC:3.1.1.4]
109063347  [KO:K00901] [EC:2.7.1.107]
109063761  [KO:K01115] [EC:3.1.4.4]
109064142  chata; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
109064430  cept1b; choline/ethanolaminephosphotransferase 1b [KO:K13644] [EC:2.7.8.1 2.7.8.2]
109064987  [KO:K00968] [EC:2.7.7.15]
109065111  [KO:K00968] [EC:2.7.7.15]
109065967  [KO:K01047] [EC:3.1.1.4]
109066018  [KO:K00006] [EC:1.1.1.8]
109066047  [KO:K14676] [EC:3.1.1.5]
109066299  [KO:K16343] [EC:3.1.1.4]
109067044  pla2g4f.1; cytosolic phospholipase A2 zeta isoform X1 [KO:K16342] [EC:3.1.1.4]
109067133  proca1; uncharacterized protein proca1 [KO:K01047] [EC:3.1.1.4]
109068416  [KO:K00894] [EC:2.7.1.82]
109068570  [KO:K01047] [EC:3.1.1.4]
109068639  [KO:K13506] [EC:2.3.1.15]
109069295  [KO:K08744] [EC:2.7.8.41]
109069543  [KO:K01115] [EC:3.1.4.4]
109069658  [KO:K01080] [EC:3.1.3.4]
109070362  [KO:K13506] [EC:2.3.1.15]
109071219  [KO:K16860] [EC:3.1.4.4]
109071627  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
109071631  [KO:K16342] [EC:3.1.1.4]
109071984  [KO:K00006] [EC:1.1.1.8]
109073159  [KO:K16342] [EC:3.1.1.4]
109073168  [KO:K00623] [EC:2.3.1.6]
109073266  tafazzin; tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
109073723  [KO:K00623] [EC:2.3.1.6]
109073766  [KO:K14676] [EC:3.1.1.5]
109073953  etnppl; LOW QUALITY PROTEIN: ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
109074258  [KO:K18695] [EC:3.1.4.2]
109074382  [KO:K01080] [EC:3.1.3.4]
109074386  [KO:K01080] [EC:3.1.3.4]
109074435  [KO:K16342] [EC:3.1.1.4]
109074470  [KO:K00901] [EC:2.7.1.107]
109074483  pla2g4f.2; cytosolic phospholipase A2 zeta [KO:K16342] [EC:3.1.1.4]
109074801  mboat7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
109074931  [KO:K00894] [EC:2.7.1.82]
109075570  pld1b; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
109075924  [KO:K00649] [EC:2.3.1.42]
109076969  [KO:K00901] [EC:2.7.1.107]
109078719  pemt; phosphatidylethanolamine N-methyltransferase isoform X1 [KO:K00551] [EC:2.1.1.17 2.1.1.71]
109078885  plb1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
109078932  [KO:K16342] [EC:3.1.1.4]
109078942  [KO:K16342] [EC:3.1.1.4]
109078955  [KO:K16342] [EC:3.1.1.4]
109078965  [KO:K16342] [EC:3.1.1.4]
109079487  [KO:K00967] [EC:2.7.7.14]
109079880  dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
109080684  [KO:K00629] [EC:2.3.1.15]
109080906  chpt1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
109081567  pnpla7b; patatin-like phospholipase domain-containing protein 7 [KO:K14676] [EC:3.1.1.5]
109081746  [KO:K13515] [EC:2.3.1.23 2.3.1.-]
109081938  [KO:K16342] [EC:3.1.1.4]
109081945  [KO:K01047] [EC:3.1.1.4]
109082187  [KO:K05929] [EC:2.1.1.103]
109082280  [KO:K16342] [EC:3.1.1.4]
109082869  [KO:K16342] [EC:3.1.1.4]
109083124  [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
109083276  [KO:K13516] [EC:2.3.1.-]
109083897  [KO:K13506] [EC:2.3.1.15]
109084941  [KO:K13510] [EC:2.3.1.23 2.3.1.67]
109084978  [KO:K13510] [EC:2.3.1.23 2.3.1.67]
109086484  [KO:K00901] [EC:2.7.1.107]
109087247  sgms1b; phosphatidylcholine:ceramide cholinephosphotransferase 1 [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
109087381  gpat2; glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
109087389  lypla1; acyl-protein thioesterase 1 isoform X1 [KO:K06128] [EC:3.1.1.5]
109087492  [KO:K01115] [EC:3.1.4.4]
109087533  [KO:K00901] [EC:2.7.1.107]
109088171  [KO:K01613] [EC:4.1.1.65]
109088546  [KO:K00901] [EC:2.7.1.107]
109089505  [KO:K01047] [EC:3.1.1.4]
109090128  pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
109090706  agpat9l; glycerol-3-phosphate acyltransferase 3-like [KO:K13506] [EC:2.3.1.15]
109090769  [KO:K00981] [EC:2.7.7.41]
109090770  cds1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
109092018  [KO:K00901] [EC:2.7.1.107]
109092030  [KO:K00111] [EC:1.1.5.3]
109092791  [KO:K00901] [EC:2.7.1.107]
109093003  [KO:K13512] [EC:2.3.1.23 2.3.1.-]
109093326  [KO:K00901] [EC:2.7.1.107]
109094158  [KO:K00993] [EC:2.7.8.1]
109094243  [KO:K05929] [EC:2.1.1.103]
109094445  gpd1a; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
109094545  [KO:K13517] [EC:2.3.1.51 2.3.1.-]
109095638  plpp2b; phospholipid phosphatase 2b [KO:K01080] [EC:3.1.3.4]
109095639  [KO:K00901] [EC:2.7.1.107]
109095662  [KO:K13506] [EC:2.3.1.15]
109095691  [KO:K00901] [EC:2.7.1.107]
109095693  [KO:K00901] [EC:2.7.1.107]
109095713  [KO:K00901] [EC:2.7.1.107]
109095978  [KO:K13523] [EC:2.3.1.51 2.3.1.-]
109096077  agpat4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
109096824  [KO:K01080] [EC:3.1.3.4]
109097454  [KO:K01047] [EC:3.1.1.4]
109097795  plpp1a; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
109098147  [KO:K13506] [EC:2.3.1.15]
109098156  [KO:K13506] [EC:2.3.1.15]
109098235  dgkab; LOW QUALITY PROTEIN: diacylglycerol kinase, alpha b [KO:K00901] [EC:2.7.1.107]
109099037  [KO:K00894] [EC:2.7.1.82]
109099437  [KO:K01115] [EC:3.1.4.4]
109099488  [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
109099955  gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
109100058  mboat1; lysophospholipid acyltransferase 1 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
109100146  [KO:K18693] [EC:3.6.1.75 3.1.3.4]
109100157  [KO:K18693] [EC:3.6.1.75 3.1.3.4]
109100378  [KO:K01047] [EC:3.1.1.4]
109100626  [KO:K14676] [EC:3.1.1.5]
109101067  [KO:K13513] [EC:2.3.1.- 2.3.1.51]
109101549  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
109101550  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
109101880  pcyt1aa; choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
109101990  plpp2a; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
109103884  adprm; LOW QUALITY PROTEIN: manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
109104043  [KO:K00981] [EC:2.7.7.41]
109104610  [KO:K06124] [EC:3.1.3.75]
109105148  [KO:K19007] [EC:2.3.1.51]
109105349  [KO:K13509] [EC:2.3.1.51]
109105508  [KO:K13510] [EC:2.3.1.23 2.3.1.67]
109106529  [KO:K00111] [EC:1.1.5.3]
109106849  [KO:K13517] [EC:2.3.1.51 2.3.1.-]
109106932  samd8; sphingomyelin synthase-related protein 1 isoform X1 [KO:K22697] [EC:2.7.8.48 3.1.4.62]
109106945  etnk1; ethanolamine kinase 1 isoform X1 [KO:K00894] [EC:2.7.1.82]
109107104  [KO:K15728] [EC:3.1.3.4]
109107105  lpin1a; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
109108215  [KO:K00623] [EC:2.3.1.6]
109108578  [KO:K16860] [EC:3.1.4.4]
109108707  [KO:K00629] [EC:2.3.1.15]
109108897  [KO:K14156] [EC:2.7.1.32 2.7.1.82]
109108903  [KO:K14156] [EC:2.7.1.32 2.7.1.82]
109108912  [KO:K16860] [EC:3.1.4.4]
109108971  [KO:K01047] [EC:3.1.1.4]
109108972  [KO:K01047] [EC:3.1.1.4]
109109214  [KO:K00967] [EC:2.7.7.14]
109109880  [KO:K01047] [EC:3.1.1.4]
109110059  [KO:K15728] [EC:3.1.3.4]
109110075  [KO:K22697] [EC:2.7.8.48 3.1.4.62]
109110086  [KO:K22697] [EC:2.7.8.48 3.1.4.62]
109110126  [KO:K14156] [EC:2.7.1.32 2.7.1.82]
109110357  [KO:K00999] [EC:2.7.8.11]
109110368  [KO:K00999] [EC:2.7.8.11]
109110525  [KO:K01047] [EC:3.1.1.4]
109110827  [KO:K13510] [EC:2.3.1.23 2.3.1.67]
109110928  [KO:K00993] [EC:2.7.8.1]
109111002  [KO:K08729] [EC:2.7.8.-]
109111680  [KO:K08729] [EC:2.7.8.-]
109111730  lypla2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
109111737  [KO:K06130] [EC:3.1.1.5]
109112618  pcyt1ba; choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
109112763  pla2g4ab; cytosolic phospholipase A2 isoform X1 [KO:K16342] [EC:3.1.1.4]
109112773  mboat2b; lysophospholipid acyltransferase 2b [KO:K13517] [EC:2.3.1.51 2.3.1.-]
109112871  [KO:K15728] [EC:3.1.3.4]
109112872  [KO:K00649] [EC:2.3.1.42]
109112877  [KO:K15728] [EC:3.1.3.4]
109113116  [KO:K00649] [EC:2.3.1.42]
109113254  [KO:K00649] [EC:2.3.1.42]
109113303  [KO:K01080] [EC:3.1.3.4]
109113307  [KO:K01080] [EC:3.1.3.4]
109113359  [KO:K01080] [EC:3.1.3.4]
109113827  lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
122134067  [KO:K13523] [EC:2.3.1.51 2.3.1.-]
122137324  [KO:K16342] [EC:3.1.1.4]
122138134  [KO:K01047] [EC:3.1.1.4]
122138498  pla1a; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
122139686  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
122140157  sgms1a; phosphatidylcholine:ceramide cholinephosphotransferase 1 [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
122142347  [KO:K00999] [EC:2.7.8.11]
122145990  [KO:K00006] [EC:1.1.1.8]
122147427  [KO:K00901] [EC:2.7.1.107]
122147689  [KO:K01047] [EC:3.1.1.4]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
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Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
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Biochem Biophys Res Commun 257:50-6 (1999)
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Athenstaedt K, Daum G.
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Phosphatidic acid, a key intermediate in lipid metabolism.
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Eur J Biochem 266:1-16 (1999)
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J Biol Chem 278:2956-62 (2003)
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Pathways for phosphatidylcholine biosynthesis in bacteria.
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Microbiology 149:3461-71 (2003)
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Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
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Biochim Biophys Acta 1686:161-8 (2004)
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Related
pathway
ccar00010  Glycolysis / Gluconeogenesis
ccar00260  Glycine, serine and threonine metabolism
ccar00561  Glycerolipid metabolism
ccar00562  Inositol phosphate metabolism
ccar00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
ccar00565  Ether lipid metabolism
ccar00620  Pyruvate metabolism
KO pathway
ko00564   

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