KEGG   PATHWAY: cdet00600
Entry
cdet00600                   Pathway                                
Name
Sphingolipid metabolism - Colletotrichum destructivum
Class
Metabolism; Lipid metabolism
Pathway map
cdet00600  Sphingolipid metabolism
cdet00600

Module
cdet_M00094  Ceramide biosynthesis [PATH:cdet00600]
cdet_M00099  Sphingosine biosynthesis [PATH:cdet00600]
cdet_M00100  Sphingosine degradation [PATH:cdet00600]
Other DBs
GO: 0006665
Organism
Colletotrichum destructivum [GN:cdet]
Gene
87936695  CDEST_00192; Putative aminotransferase, class I/classII, pyridoxal phosphate-dependent transferase, major [KO:K00654] [EC:2.3.1.50]
87936846  CDEST_00343; Putative alkaline ceramidase [KO:K04711] [EC:3.5.1.-]
87936966  CDEST_00463; Putative short-chain dehydrogenase/reductase SDR, NAD(P)-binding domain superfamily [KO:K04708] [EC:1.1.1.102]
87937121  CDEST_00618; Putative TRAM1-like protein [KO:K04709] [EC:2.3.1.297]
87937729  CDEST_01226; Putative fatty acid hydroxylase [KO:K04713] [EC:1.14.18.5]
87938329  CDEST_01826; Putative glycoside hydrolase family 36, glycosyl hydrolase, all-beta, aldolase-type TIM barrel [KO:K07407] [EC:3.2.1.22]
87938748  CDEST_02245; Putative diacylglycerol kinase, catalytic domain, inorganic polyphosphate/ATP-NAD kinase [KO:K04718] [EC:2.7.1.91]
87939196  CDEST_02693; Putative glycoside hydrolase family 20, catalytic domain, glycoside hydrolase superfamily [KO:K12373] [EC:3.2.1.52]
87939800  CDEST_03297; Putative endonuclease/exonuclease/phosphatase, sphingomyelinase C/Sphingomyelin phosphodiesterase 2 [KO:K12351] [EC:3.1.4.12]
87940632  CDEST_04129; Putative Beta galactosidase small chain/domain 5, glycoside hydrolase, family 2 [KO:K01190] [EC:3.2.1.23]
87940648  CDEST_04145; Putative Beta galactosidase small chain/domain 5, glycoside hydrolase, family 2 [KO:K01190] [EC:3.2.1.23]
87940878  CDEST_04375; Putative glycoside hydrolase family 27/36, glycoside hydrolase, family 27, aldolase-type TIM barrel [KO:K07407] [EC:3.2.1.22]
87940918  CDEST_04415; Putative ceramide glucosyltransferase, nucleotide-diphospho-sugar transferase [KO:K00720] [EC:2.4.1.80]
87942399  CDEST_05896; Putative glycoside hydrolase family 27/36, glycoside hydrolase, family 27, aldolase-type TIM barrel [KO:K07407] [EC:3.2.1.22]
87942441  CDEST_05938; Putative fatty acid hydroxylase [KO:K04713] [EC:1.14.18.5]
87942442  CDEST_05939; Putative fatty acid hydroxylase [KO:K04713] [EC:1.14.18.5]
87942446  CDEST_05943; Putative short-chain dehydrogenase/reductase SDR, NAD(P)-binding domain superfamily [KO:K04708] [EC:1.1.1.102]
87943161  CDEST_06658; Putative pyridoxal phosphate-dependent decarboxylase, pyridoxal phosphate-dependent transferase [KO:K01634] [EC:4.1.2.27]
87943952  CDEST_07449; Putative phosphatidic acid phosphatase type 2/haloperoxidase [KO:K23451]
87944027  CDEST_07524; Putative beta-hexosaminidase, bacterial type, glycoside hydrolase family 20, catalytic [KO:K12373] [EC:3.2.1.52]
87944250  CDEST_07747; Putative TRAM1-like protein [KO:K04709] [EC:2.3.1.297]
87945181  CDEST_08678; Putative glycoside hydrolase, family 2, glycoside hydrolase family 2, catalytic [KO:K01190] [EC:3.2.1.23]
87945485  CDEST_08982; Putative neutral/alkaline nonlysosomal ceramidase, neutral/alkaline non-lysosomal ceramidase [KO:K12349] [EC:3.5.1.23]
87946637  CDEST_10135; Putative alkaline ceramidase [KO:K04711] [EC:3.5.1.-]
87946662  CDEST_10160; Putative aminotransferase, class I/classII, pyridoxal phosphate-dependent transferase, major [KO:K00654] [EC:2.3.1.50]
87946767  CDEST_10265; Putative TRAM1-like protein [KO:K04709] [EC:2.3.1.297]
87949268  CDEST_12768; Putative glycoside hydrolase, family 27, glycosyl hydrolase, all-beta, aldolase-type TIM barrel [KO:K07407] [EC:3.2.1.22]
87949794  CDEST_13294; Putative Beta galactosidase small chain/domain 5, glycoside hydrolase, family 2 [KO:K01190] [EC:3.2.1.23]
87949869  CDEST_13369; Putative fatty acid desaturase domain, sphingolipid delta4-desaturase [KO:K04712] [EC:1.14.19.17 1.14.18.5]
87950287  CDEST_13787; Putative neutral/alkaline nonlysosomal ceramidase, neutral/alkaline non-lysosomal ceramidase [KO:K12349] [EC:3.5.1.23]
87951347  CDEST_14847; Putative calcineurin-like phosphoesterase domain, ApaH type, sphingomyelin phosphodiesterase [KO:K12350] [EC:3.1.4.12]
87951441  CDEST_14941; Putative concanavalin A-like lectin/glucanase domain superfamily, glycoside hydrolase superfamily [KO:K12373] [EC:3.2.1.52]
87951518  CDEST_15018; Putative TRAM1-like protein [KO:K04709] [EC:2.3.1.297]
Compound
C00065  L-Serine
C00154  Palmitoyl-CoA
C00195  N-Acylsphingosine
C00319  Sphingosine
C00346  Ethanolamine phosphate
C00550  Sphingomyelin
C00836  Sphinganine
C01120  Sphinganine 1-phosphate
C01190  Glucosylceramide
C01290  Lactosylceramide
C01747  Psychosine
C02686  Galactosylceramide
C02934  3-Dehydrosphinganine
C02960  Ceramide 1-phosphate
C03108  D-Glucosylsphingosine
C03272  Globoside
C03405  Lactosylceramide sulfate
C03640  Sphingosyl-phosphocholine
C04730  GM3
C04737  alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
C04884  N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
C04911  D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
C05681  Ceramide 2-aminoethylphosphonate
C06062  Ceramide phosphoethanolamine
C06124  Sphingosine 1-phosphate
C06125  Sulfatide
C06126  Digalactosylceramide
C06127  Digalactosylceramide sulfate
C06128  GM4
C06135  GA2
C06136  GA1
C12126  Dihydroceramide
C12144  Phytosphingosine
C12145  Phytoceramide
C22467  Gangliotriaosylceramide-II3 sulfate
C23072  Oxidized ceramide
Reference
PMID:12011104
  Authors
Merrill AH Jr.
  Title
De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway.
  Journal
J Biol Chem 277:25843-6 (2002)
DOI:10.1074/jbc.R200009200
Reference
PMID:10652340
  Authors
Tani M, Okino N, Mitsutake S, Tanigawa T, Izu H, Ito M.
  Title
Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.
  Journal
J Biol Chem 275:3462-8 (2000)
DOI:10.1074/jbc.275.5.3462
Reference
PMID:11305904
  Authors
Hannun YA, Luberto C, Argraves KM.
  Title
Enzymes of sphingolipid metabolism: from modular to integrative signaling.
  Journal
Biochemistry 40:4893-903 (2001)
DOI:10.1021/bi002836k
Reference
PMID:1495423
  Authors
Merrill AH Jr, Wang E.
  Title
Enzymes of ceramide biosynthesis.
  Journal
Methods Enzymol 209:427-37 (1992)
DOI:10.1016/0076-6879(92)09053-6
Reference
PMID:8457204
  Authors
Hirschberg K, Rodger J, Futerman AH.
  Title
The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver.
  Journal
Biochem J 290 ( Pt 3):751-7 (1993)
DOI:10.1042/bj2900751
Reference
PMID:10366774
  Authors
Dickson RC, Lester RL.
  Title
Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1438:305-21 (1999)
DOI:10.1016/S1388-1981(99)00068-2
Related
pathway
cdet00260  Glycine, serine and threonine metabolism
cdet00603  Glycosphingolipid biosynthesis - globo and isoglobo series
cdet00604  Glycosphingolipid biosynthesis - ganglio series
KO pathway
ko00600   

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