KEGG   PATHWAY: cspg00230
Entry
cspg00230                   Pathway                                
Name
Purine metabolism - Cytobacillus spongiae
Class
Metabolism; Nucleotide metabolism
Pathway map
cspg00230  Purine metabolism
cspg00230

Module
cspg_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cspg00230]
cspg_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cspg00230]
cspg_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cspg00230]
cspg_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cspg00230]
cspg_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cspg00230]
Other DBs
GO: 0006163 0042278
Organism
Cytobacillus spongiae [GN:cspg]
Gene
LS684_13720  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
LS684_13690  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
LS684_04690  phospho-sugar mutase [KO:K01835] [EC:5.4.2.2]
LS684_00305  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
LS684_02300  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
LS684_02320  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
LS684_02310  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
LS684_02295  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
LS684_02285  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
LS684_02290  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
LS684_02305  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
LS684_02270  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
LS684_02265  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
LS684_02280  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
LS684_02275  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
LS684_02315  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
LS684_15235  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
LS684_13685  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
LS684_23980  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
LS684_12345  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
LS684_07810  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
LS684_22035  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
LS684_12565  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
LS684_00400  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
LS684_00075  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
LS684_13310  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
LS684_16475  DUF84 family protein [KO:K01529] [EC:3.6.1.73]
LS684_15710  XTP/dITP diphosphatase [KO:K01519] [EC:3.6.1.66]
LS684_12945  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
LS684_02170  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
LS684_22025  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
LS684_07955  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
LS684_11790  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
LS684_14290  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
LS684_11785  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
LS684_00110  deoxynucleoside kinase [KO:K15518] [EC:2.7.1.113]
LS684_15230  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
LS684_07165  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
LS684_01250  GTP pyrophosphokinase family protein [KO:K07816] [EC:2.7.6.5]
LS684_06220  GTP pyrophosphokinase family protein [KO:K07816] [EC:2.7.6.5]
LS684_20365  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
LS684_00105  deoxynucleoside kinase [KO:K15519] [EC:2.7.1.76 2.7.1.74]
LS684_02595  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
LS684_02330  amidohydrolase family protein [KO:K01486] [EC:3.5.4.2]
LS684_10110  bifunctional metallophosphatase/5'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
LS684_20650  TIGR00282 family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
LS684_08625  TIGR00282 family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
LS684_00825  adenylate kinase [KO:K00939] [EC:2.7.4.3]
LS684_22720  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
LS684_22725  sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cspg00030  Pentose phosphate pathway
cspg00220  Arginine biosynthesis
cspg00250  Alanine, aspartate and glutamate metabolism
cspg00260  Glycine, serine and threonine metabolism
cspg00340  Histidine metabolism
cspg00630  Glyoxylate and dicarboxylate metabolism
cspg00730  Thiamine metabolism
cspg00740  Riboflavin metabolism
cspg00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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