KEGG   PATHWAY: eame00230
Entry
eame00230                   Pathway                                
Name
Purine metabolism - Ewingella americana
Class
Metabolism; Nucleotide metabolism
Pathway map
eame00230  Purine metabolism
eame00230

Module
eame_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:eame00230]
eame_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:eame00230]
eame_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:eame00230]
eame_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:eame00230]
Other DBs
GO: 0006163 0042278
Organism
Ewingella americana [GN:eame]
Gene
GXP68_02235  nudF; ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
GXP68_01050  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
GXP68_17855  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
GXP68_02835  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
GXP68_15035  pgm; alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
GXP68_09430  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
GXP68_06560  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
GXP68_19710  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
GXP68_05565  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
GXP68_08005  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
GXP68_05570  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
GXP68_04940  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
GXP68_04945  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
GXP68_05625  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
GXP68_07810  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
GXP68_19705  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
GXP68_04765  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
GXP68_16955  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
GXP68_15105  HAD-IIA family hydrolase [KO:K02566] [EC:3.1.3.5]
GXP68_04825  inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
GXP68_13025  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
GXP68_17850  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
GXP68_04320  ppnP; pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
GXP68_16485  pgeF; polyphenol oxidase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
GXP68_05725  nucleoside hydrolase [KO:K25589] [EC:3.2.2.2 3.2.2.3]
GXP68_17265  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
GXP68_15500  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
GXP68_15585  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
GXP68_17795  yjjX; non-canonical purine NTP phosphatase [KO:K01529] [EC:3.6.1.73]
GXP68_02740  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
GXP68_16110  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
GXP68_15495  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
GXP68_17370  GMP reductase [KO:K00364] [EC:1.7.1.7]
GXP68_20925  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
GXP68_03880  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
GXP68_06820  nrdA; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
GXP68_03875  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
GXP68_06815  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
GXP68_19000  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
GXP68_17120  dgt; dGTPase [KO:K01129] [EC:3.1.5.1]
GXP68_06675  yfbR; 5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
GXP68_05855  HD family hydrolase [KO:K06952] [EC:3.1.3.89]
GXP68_20935  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
GXP68_15340  phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
GXP68_20405  gppA; guanosine-5'-triphosphate,3'-diphosphate diphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
GXP68_05550  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
GXP68_17070  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
GXP68_20285  class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
GXP68_14975  3',5'-cyclic-nucleotide phosphodiesterase [KO:K01120] [EC:3.1.4.17]
GXP68_19440  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
GXP68_10815  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
GXP68_22555  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
GXP68_03525  LOG family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
GXP68_04680  adenine deaminase [KO:K01486] [EC:3.5.4.2]
GXP68_19370  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
GXP68_04815  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
GXP68_17065  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
GXP68_03055  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
GXP68_17620  apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [KO:K01525] [EC:3.6.1.41]
GXP68_16985  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
GXP68_16990  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
GXP68_16995  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
GXP68_16285  hpxA; allantoin racemase [KO:K16841] [EC:5.1.99.3]
GXP68_00715  amidohydrolase family protein [KO:K01466] [EC:3.5.2.5]
GXP68_16280  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
GXP68_16225  hpxK; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
GXP68_16230  alanine--glyoxylate aminotransferase family protein [KO:K00839] [EC:2.6.1.112]
GXP68_18210  allE; (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
GXP68_01745  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
GXP68_18225  allD; ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
GXP68_16270  AtzE family amidohydrolase [KO:K22601] [EC:2.1.3.5]
GXP68_16260  gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
GXP68_18245  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
eame00030  Pentose phosphate pathway
eame00220  Arginine biosynthesis
eame00250  Alanine, aspartate and glutamate metabolism
eame00260  Glycine, serine and threonine metabolism
eame00340  Histidine metabolism
eame00630  Glyoxylate and dicarboxylate metabolism
eame00730  Thiamine metabolism
eame00740  Riboflavin metabolism
eame00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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