KEGG   PATHWAY: eay00230
Entry
eay00230                    Pathway                                
Name
Purine metabolism - Erwinia amylovora ATCC 49946
Class
Metabolism; Nucleotide metabolism
Pathway map
eay00230  Purine metabolism
eay00230

Module
eay_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:eay00230]
eay_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:eay00230]
eay_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:eay00230]
eay_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:eay00230]
eay_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:eay00230]
Other DBs
GO: 0006163 0042278
Organism
Erwinia amylovora ATCC 49946 [GN:eay]
Gene
EAM_2987  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
EAM_3247  nudE; ADP compounds hydrolase [KO:K08312] [EC:3.6.1.-]
EAM_0617  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
EAM_1156  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
EAM_1582  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
EAM_2318  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
EAM_0248  purD; phosphoribosylglycineamide synthetase [KO:K01945] [EC:6.3.4.13]
EAM_0407  putative phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
EAM_2442  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
EAM_1994  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
EAM_2502  purL; Phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
EAM_2441  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
EAM_1059  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
EAM_1060  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
EAM_2430  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
EAM_1515  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
EAM_0249  purH; bifunctional purine biosynthesis protein PurH [includes phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase] [KO:K00602] [EC:2.1.2.3 3.5.4.10]
EAM_1023  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
EAM_1039  ushA; protein UshA precursor [includes: UDP-sugar hydrolase; 5'-nucleotidas] [KO:K11751] [EC:3.1.3.5 3.6.1.45]
EAM_2682  surE; multifunctional protein (stationary-phase survival protein SurE) [includes: 5'/3'-nucleotidase; exopolyphosphatase] [KO:K03787] [EC:3.1.3.5 3.1.3.6]
EAM_1144  nagD; ribonucleotide monophosphatase [KO:K02566] [EC:3.1.3.5]
EAM_1035  gsk; inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
EAM_0618  deoD; purine nucleoside phosphorylase DeoD-type [KO:K03784] [EC:2.4.2.1]
EAM_0938  conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
EAM_2614  conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
EAM_0783  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
EAM_2465  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
EAM_2479  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
EAM_0635  conserved hypothetical protein [KO:K01529] [EC:3.6.1.73]
EAM_2841  Ham1 protein homolog [KO:K01519] [EC:3.6.1.66]
EAM_0896  gpt; xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
EAM_2464  guaA; GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
EAM_0728  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
EAM_1716  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
EAM_0045  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
EAM_2266  nrdA; ribonucleoside-diphosphate reductase 1 alpha subunit [KO:K00525] [EC:1.17.4.1]
EAM_2596  nrdE; ribonucleoside-diphosphate reductase 2 alpha chain [KO:K00525] [EC:1.17.4.1]
EAM_2267  nrdB; ribonucleoside-diphosphate reductase 1 beta subunit [KO:K00526] [EC:1.17.4.1]
EAM_2597  nrdF; ribonucleoside-diphosphate reductase 2 beta chain [KO:K00526] [EC:1.17.4.1]
EAM_3059  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
EAM_0813  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
EAM_2295  yfbR; putative nucleoside 5'-monophosphate phosphohydrolase [KO:K08722] [EC:3.1.3.89]
EAM_0043  spoT; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
EAM_0160  gppA; guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (guanosine pentaphosphatase) [KO:K01524] [EC:3.6.1.11 3.6.1.40]
EAM_2447  ppx; putative exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
EAM_2706  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
EAM_0181  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
EAM_0441  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
EAM_1703  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
EAM_2118  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
EAM_2715  conserved hypothetical protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
EAM_0454  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
EAM_1033  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
EAM_2705  mazG; putative nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
EAM_2985  icc; putative phosphoesterase [KO:K03651] [EC:3.1.4.53]
EAM_0664  apaH; bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
EAM_2688  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
EAM_2689  cysN; Sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
EAM_2690  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
EAM_1718  putative hydroxylase [KO:K16839] [EC:1.14.13.113]
EAM_0879  putative purine catabolism-related protein [KO:K07127] [EC:3.5.2.17]
EAM_0878  conserved hypothetical protein [KO:K16840] [EC:4.1.1.97]
EAM_0860  hyuE; putative hydantoin racemase [KO:K16841] [EC:5.1.99.3]
EAM_0861  putative polysaccharide deacetylase [KO:K16842] [EC:3.5.2.5]
EAM_0877  putative peptidase/hydantoinase/carbamoylase [KO:K02083] [EC:3.5.3.9]
EAM_0876  putative aminotransferase [KO:K00839] [EC:2.6.1.112]
EAM_0866  probable amidase [KO:K22601] [EC:2.1.3.5]
EAM_0868  putative gamma-glutamyltranspeptidase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
eay00030  Pentose phosphate pathway
eay00220  Arginine biosynthesis
eay00250  Alanine, aspartate and glutamate metabolism
eay00260  Glycine, serine and threonine metabolism
eay00340  Histidine metabolism
eay00630  Glyoxylate and dicarboxylate metabolism
eay00730  Thiamine metabolism
eay00740  Riboflavin metabolism
eay00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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