KEGG   PATHWAY: ece00630
Entry
ece00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Escherichia coli O157:H7 EDL933 (EHEC)
Class
Metabolism; Carbohydrate metabolism
Pathway map
ece00630  Glyoxylate and dicarboxylate metabolism
ece00630

Module
ece_M00012  Glyoxylate cycle [PATH:ece00630]
ece_M00621  Glycine cleavage system [PATH:ece00630]
Other DBs
GO: 0046487 0043648
Organism
Escherichia coli O157:H7 EDL933 (EHEC) [GN:ece]
Gene
Z0126  lpdA; lipoamide dehydrogenase (NADH); component of 2-oxodehydrogenase and pyruvate complexes; L-protein of glycine cleavage complex [KO:K00382] [EC:1.8.1.4]
Z0128  acnB; aconitate hydrase B [KO:K01682] [EC:4.2.1.3 4.2.1.99]
Z0428  prpC; putative citrate synthase; propionate metabolism [KO:K01659] [EC:2.3.3.5]
Z0661  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
Z0662  gip; glyoxylate-induced protein [KO:K01816] [EC:5.3.1.22]
Z0663  ybbQ; putative oxidoreductase [KO:K00042] [EC:1.1.1.60]
Z0669  ybbZ; orf, hypothetical protein [KO:K00865] [EC:2.7.1.165]
Z0873  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
Z0892  [KO:K04835] [EC:4.3.1.2]
Z0893  [KO:K19268] [EC:5.4.99.1]
Z0895  [KO:K01846] [EC:5.4.99.1]
Z1666  ycdW; putative dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
Z2008  purU; formyltetrahydrofolate deformylase; for purT-dependent FGAR synthesis [KO:K01433] [EC:3.5.1.10]
Z2306  aldA; aldehyde dehydrogenase, NAD-linked [KO:K07248] [EC:1.2.1.22 1.2.1.21]
Z2532  acnA; aconitate hydrase 1 [KO:K27802]
Z2761  katE; catalase; hydroperoxidase HPII(III) [KO:K03781] [EC:1.11.1.6]
Z2843  yeaU; putative tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Z2902  eda; 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Z3637  [KO:K01577] [EC:4.1.1.8]
Z3639  [KO:K07749] [EC:2.8.3.16]
Z3827  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Z4116  fucO; L-1,2-propanediol oxidoreductase [KO:K00048] [EC:1.1.1.77]
Z4164  yqeF; putative acyltransferase [KO:K00626] [EC:2.3.1.9]
Z4240  gcvP; glycine decarboxylase, P protein of glycine cleavage system [KO:K00281] [EC:1.4.4.2]
Z4241  gcvH; in glycine cleavage complex, carrier of aminomethyl moiety via covalently bound lipoyl cofactor [KO:K02437]
Z4242  gcvT; aminomethyltransferase (T protein; tetrahydrofolate-dependent) of glycine cleavage system [KO:K00605] [EC:2.1.2.10]
Z4254  sbm; methylmalonyl-CoA mutase (MCM) [KO:K01847] [EC:5.4.99.2]
Z4414  ttdA; L-tartrate dehydratase, subunit A [KO:K03779] [EC:4.2.1.32]
Z4415  ttdB; L-tartrate dehydratase, subunit B [KO:K03780] [EC:4.2.1.32]
Z4476  yhaD; orf, hypothetical protein [KO:K00865] [EC:2.7.1.165]
Z4477  yhaE; putative dehydrogenase [KO:K00042] [EC:1.1.1.60]
Z4595  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Z4738  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Z4978  yiaE; putative dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
Z5406  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Z5434  fdoI; formate dehydrogenase, cytochrome B556 (FDO) subunit [KO:K00127]
Z5435  fdoH; formate dehydrogenase-O, iron-sulfur subunit [KO:K00124]
Z5436  fdoG; formate dehydrogenase-O, major subunit [KO:K00123] [EC:1.17.1.9]
Z5600  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
Z5601  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
Z5668  acs; acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00049  L-Aspartate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C05840  Iminoaspartate
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C19838  D-erythro-3-Hydroxyaspartate
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
ece00010  Glycolysis / Gluconeogenesis
ece00020  Citrate cycle (TCA cycle)
ece00030  Pentose phosphate pathway
ece00053  Ascorbate and aldarate metabolism
ece00071  Fatty acid degradation
ece00230  Purine metabolism
ece00250  Alanine, aspartate and glutamate metabolism
ece00260  Glycine, serine and threonine metabolism
ece00270  Cysteine and methionine metabolism
ece00620  Pyruvate metabolism
ece00710  Carbon fixation by Calvin cycle
ece00750  Vitamin B6 metabolism
ece00910  Nitrogen metabolism
KO pathway
ko00630   

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