KEGG   PATHWAY: ecj00240
Entry
ecj00240                    Pathway                                
Name
Pyrimidine metabolism - Escherichia coli K-12 W3110
Class
Metabolism; Nucleotide metabolism
Pathway map
ecj00240  Pyrimidine metabolism
ecj00240

Module
ecj_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:ecj00240]
ecj_M00052  Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:ecj00240]
ecj_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ecj00240]
ecj_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:ecj00240]
ecj_M00939  Pyrimidine degradation, uracil => 3-hydroxypropanoate [PATH:ecj00240]
Other DBs
GO: 0006220 0006213
Organism
Escherichia coli K-12 W3110 [GN:ecj]
Gene
JW0028  rihC; ribonucleoside hydrolase 3 [KO:K12700] [EC:3.2.2.-]
JW0030  carA; carbamoyl phosphate synthetase small subunit, glutamine amidotransferase [KO:K01956] [EC:6.3.5.5]
JW0031  carB; carbamoyl-phosphate synthase large subunit [KO:K01955] [EC:6.3.5.5]
JW0166  pyrH; uridylate kinase [KO:K09903] [EC:2.7.4.22]
JW0328  codA; cytosine deaminase [KO:K01485] [EC:3.5.4.1 3.5.4.21]
JW0382  yaiE; conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
JW0469  ushA; bifunctional UDP-sugar hydrolase and 5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
JW0646  rihA; ribonucleoside hydrolase 1 [KO:K01250] [EC:3.2.2.-]
JW0661  nagD; UMP phosphatase [KO:K02566] [EC:3.1.3.5]
JW0893  cmk; cytidylate kinase [KO:K00945] [EC:2.7.4.25]
JW0928  pyrD; dihydro-orotate oxidase, FMN-linked [KO:K00254] [EC:1.3.5.2]
JW0993  ycdI; predicted oxidoreductase [KO:K09019] [EC:1.1.1.-]
JW0994  rarA; predicted hydrolase [KO:K09023] [EC:3.5.1.-]
JW0995  ycdK; conserved hypothetical protein [KO:K09021]
JW0997  ycdM; predicted monooxygenase [KO:K09018] [EC:1.14.99.46]
JW1049  pyrC; dihydro-orotase [KO:K01465] [EC:3.5.2.3]
JW1084  tmk; thymidylate kinase [KO:K00943] [EC:2.7.4.9]
JW1226  tdk; thymidine kinase/deoxyuridine kinase [KO:K00857] [EC:2.7.1.21]
JW1273  pyrF; orotidine-5'-phosphate decarboxylase [KO:K01591] [EC:4.1.1.23]
JW1532  ydfG; L-allo-threonine dehydrogenase, NAD(P)-binding [KO:K16066] [EC:1.1.1.381 1.1.1.-]
JW1748  nudG; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase [KO:K08320] [EC:3.6.1.65]
JW2050  dcd; 2'-deoxycytidine 5'-triphosphate deaminase [KO:K01494] [EC:3.5.4.13]
JW2051  udk; uridine/cytidine kinase [KO:K00876] [EC:2.7.1.48]
JW2131  cdd; cytidine/deoxycytidine deaminase [KO:K01489] [EC:3.5.4.5]
JW2133  yeiT; predicted oxidoreductase [KO:K17722] [EC:1.3.1.1]
JW2134  yeiA; predicted oxidoreductase [KO:K17723] [EC:1.3.1.1]
JW2149  rihB; ribonucleoside hydrolase 2 [KO:K10213] [EC:3.2.2.8]
JW2152  yeiN; conserved hypothetical protein [KO:K16329] [EC:4.2.1.70]
JW2153  yeiC; predicted kinase [KO:K16328] [EC:2.7.1.83]
JW2228  nrdA; ribonucleoside diphosphate reductase 1, alpha subunit [KO:K00525] [EC:1.17.4.1]
JW2229  nrdB; ribonucleoside diphosphate reductase 1, beta subunit, ferritin-like [KO:K00526] [EC:1.17.4.1]
JW2288  yfbR; deoxyribonucleoside 5'-monophosphatase [KO:K08722] [EC:3.1.3.89]
JW2358  yfdR; conserved hypothetical protein [KO:K06952] [EC:3.1.3.89]
JW2483  upp; uracil phosphoribosyltransferase [KO:K00761] [EC:2.4.2.9]
JW2502  ndk; multifunctional nucleoside diphosphate kinase, apyrimidinic endonuclease, and 3'-phosphodiesterase [KO:K00940] [EC:2.7.4.6]
JW2650  nrdE; ribonucleoside-diphosphate reductase 2, alpha subunit [KO:K00525] [EC:1.17.4.1]
JW2651  nrdF; ribonucleoside-diphosphate reductase 2, beta subunit, ferritin-like [KO:K00526] [EC:1.17.4.1]
JW2714  surE; broad specificity 5'(3')-nucleotidase and polyphosphatase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
JW2751  pyrG; CTP synthetase [KO:K01937] [EC:6.3.4.2]
JW2752  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
JW2766  ygdH; conserved hypothetical protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
JW2795  thyA; thymidylate synthetase [KO:K00560] [EC:2.1.1.45]
JW2841  hyuA; D-stereospecific phenylhydantoinase [KO:K01464] [EC:3.5.2.2]
JW3217  yhdE; conserved hypothetical protein [KO:K06287] [EC:3.6.1.-]
JW3615  dut; deoxyuridinetriphosphatase [KO:K01520] [EC:3.6.1.23]
JW3617  pyrE; orotate phosphoribosyltransferase [KO:K00762] [EC:2.4.2.10]
JW3808  udp; uridine phosphorylase [KO:K00757] [EC:2.4.2.3]
JW4171  cpdB; 2':3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
JW4197  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
JW4203  pyrI; aspartate carbamoyltransferase, regulatory subunit [KO:K00610]
JW4204  pyrB; aspartate carbamoyltransferase, catalytic subunit [KO:K00609] [EC:2.1.3.2]
JW4336  yjjG; predicted hydrolase [KO:K08723] [EC:3.1.3.-]
JW4345  deoA; thymidine phosphorylase [KO:K00758] [EC:2.4.2.4]
JW5138  ycdH; predicted oxidoreductase, flavin:NADH component [KO:K09024] [EC:1.5.1.-]
JW5139  ycdL; hypothetical protein [KO:K09020] [EC:3.5.1.110]
JW5514  ygjP; predicted metal dependent hydrolase [KO:K07043] [EC:3.6.1.-]
Compound
C00015  UDP
C00039  DNA
C00046  RNA
C00055  CMP
C00063  CTP
C00064  L-Glutamine
C00075  UTP
C00086  Urea
C00099  beta-Alanine
C00105  UMP
C00106  Uracil
C00112  CDP
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00169  Carbamoyl phosphate
C00178  Thymine
C00214  Thymidine
C00222  3-Oxopropanoate
C00239  dCMP
C00295  Orotate
C00299  Uridine
C00337  (S)-Dihydroorotate
C00363  dTDP
C00364  dTMP
C00365  dUMP
C00380  Cytosine
C00383  Malonate
C00429  5,6-Dihydrouracil
C00438  N-Carbamoyl-L-aspartate
C00458  dCTP
C00459  dTTP
C00460  dUTP
C00475  Cytidine
C00526  Deoxyuridine
C00672  2-Deoxy-D-ribose 1-phosphate
C00705  dCDP
C00813  Barbiturate
C00881  Deoxycytidine
C00941  3',5'-Cyclic CMP
C01013  3-Hydroxypropanoate
C01103  Orotidine 5'-phosphate
C01168  Pseudouridine 5'-phosphate
C01205  (R)-3-Amino-2-methylpropanoate
C01346  dUDP
C01368  3'-UMP
C01563  Carbamate
C02067  Pseudouridine
C02170  Methylmalonate
C02354  2',3'-Cyclic CMP
C02355  2',3'-Cyclic UMP
C02376  5-Methylcytosine
C02642  3-Ureidopropionate
C03997  5-Hydroxymethyldeoxycytidylate
C05281  5-Methylbarbiturate
C05822  3'-CMP
C06198  P1,P4-Bis(5'-uridyl) tetraphosphate
C11038  2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate
C11039  2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate
C15607  3-Oxo-3-ureidopropanoate
C20231  (Z)-3-Ureidoacrylate peracid
C20249  (Z)-3-Peroxyaminoacrylate
C20253  Aminoacrylate
C20254  Ureidoacrylate
C20846  3-Oxo-3-ureidoisobutyrate
C21028  (R)-5,6-Dihydrothymine
C21029  (R)-3-Ureidoisobutyrate
C22509  3',5'-Cyclic UMP
Related
pathway
ecj00030  Pentose phosphate pathway
ecj00220  Arginine biosynthesis
ecj00250  Alanine, aspartate and glutamate metabolism
ecj00280  Valine, leucine and isoleucine degradation
ecj00410  beta-Alanine metabolism
KO pathway
ko00240   

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