KEGG   PATHWAY: ecob00230
Entry
ecob00230                   Pathway                                
Name
Purine metabolism - Escherichia coli B C3029
Class
Metabolism; Nucleotide metabolism
Pathway map
ecob00230  Purine metabolism
ecob00230

Module
ecob_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ecob00230]
ecob_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ecob00230]
ecob_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ecob00230]
ecob_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ecob00230]
ecob_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ecob00230]
ecob_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:ecob00230]
ecob_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:ecob00230]
Other DBs
GO: 0006163 0042278
Organism
Escherichia coli B C3029 [GN:ecob]
Gene
C3029_19165  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
C3029_21000  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
C3029_20915  mutase [KO:K01839] [EC:5.4.2.7]
C3029_03425  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
C3029_07055  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
C3029_10425  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
C3029_15745  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
C3029_01660  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
C3029_16575  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
C3029_13700  phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
C3029_16875  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
C3029_16570  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
C3029_06210  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
C3029_06215  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
C3029_16450  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
C3029_10125  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
C3029_01665  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
C3029_05955  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
C3029_06010  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
C3029_17685  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
C3029_06980  UMP phosphatase [KO:K02566] [EC:3.1.3.5]
C3029_21010  GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
C3029_05995  inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
C3029_03420  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
C3029_05530  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
C3029_17090  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
C3029_04375  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
C3029_16620  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
C3029_16670  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
C3029_03365  yjjX; inositol monophosphatase [KO:K01529] [EC:3.6.1.73]
C3029_18715  non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
C3029_04970  xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
C3029_18260  xanthine dehydrogenase [KO:K00087] [EC:1.17.1.4]
C3029_18265  xanthine dehydrogenase [KO:K13479] [EC:1.17.1.4]
C3029_18270  xanthine dehydrogenase [KO:K13480]
C3029_05020  xanthine dehydrogenase [KO:K11177] [EC:1.17.1.4]
C3029_05025  xanthine dehydrogenase [KO:K11178] [EC:1.17.1.4]
C3029_05030  aldehyde oxidoreductase [KO:K13483]
C3029_16615  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
C3029_04270  guanosine monophosphate reductase [KO:K00364] [EC:1.7.1.7]
C3029_18625  guanine deaminase [KO:K01487] [EC:3.5.4.3]
C3029_22370  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
C3029_15355  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
C3029_17335  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
C3029_15360  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
C3029_17340  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
C3029_02890  anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
C3029_04575  dgt; dGTPase [KO:K01129] [EC:3.1.5.1]
C3029_15635  5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
C3029_22380  (p)ppGpp synthetase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
C3029_16585  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
C3029_00390  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
C3029_17855  relA; (p)ppGpp synthetase [KO:K00951] [EC:2.7.6.5]
C3029_00535  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
C3029_02575  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
C3029_12465  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
C3029_14105  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
C3029_17915  LOG family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
C3029_22565  adenosine deaminase [KO:K01486] [EC:3.5.4.2]
C3029_02785  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
C3029_05980  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
C3029_17840  mazG; nucleoside triphosphate hydrolase [KO:K04765] [EC:3.6.1.9]
C3029_19155  diguanylate phosphodiesterase [KO:K03651] [EC:3.1.4.53]
C3029_04000  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
C3029_17715  adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
C3029_17720  cysN; sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
C3029_17725  sulfate adenylyltransferase [KO:K00957] [EC:2.7.7.4]
C3029_14045  5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
C3029_06160  cyclic amidohydrolase [KO:K01466] [EC:3.5.2.5]
C3029_06180  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
C3029_06175  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
C3029_06130  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
C3029_06185  ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
C3029_18300  carbamate kinase [KO:K00926] [EC:2.7.2.2]
C3029_00690  carbamate kinase [KO:K00926] [EC:2.7.2.2]
C3029_05215  carbamate kinase [KO:K00926] [EC:2.7.2.2]
C3029_06205  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ecob00030  Pentose phosphate pathway
ecob00220  Arginine biosynthesis
ecob00250  Alanine, aspartate and glutamate metabolism
ecob00260  Glycine, serine and threonine metabolism
ecob00340  Histidine metabolism
ecob00630  Glyoxylate and dicarboxylate metabolism
ecob00730  Thiamine metabolism
ecob00740  Riboflavin metabolism
ecob00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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