KEGG   PATHWAY: ehu00230
Entry
ehu00230                    Pathway                                
Name
Purine metabolism - Enterobacter huaxiensis
Class
Metabolism; Nucleotide metabolism
Pathway map
ehu00230  Purine metabolism
ehu00230

Module
ehu_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ehu00230]
ehu_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ehu00230]
ehu_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ehu00230]
ehu_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ehu00230]
ehu_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ehu00230]
Other DBs
GO: 0006163 0042278
Organism
Enterobacter huaxiensis [GN:ehu]
Gene
D5067_0003445  ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
D5067_0001720  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
D5067_0019760  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
D5067_0016400  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
D5067_0009990  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
D5067_0007130  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
D5067_0022010  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
D5067_0006445  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
D5067_0009360  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
D5067_0006145  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
D5067_0006450  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
D5067_0017430  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
D5067_0017425  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
D5067_0006530  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
D5067_0013965  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
D5067_0022005  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
D5067_0017565  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
D5067_0017515  bifunctional UDP-sugar hydrolase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
D5067_0004870  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
D5067_0016470  nagD; ribonucleotide monophosphatase NagD [KO:K02566] [EC:3.1.3.5]
D5067_0001710  GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
D5067_0017530  inosine/guanosine kinase [KO:K00892] [EC:2.7.1.73]
D5067_0019755  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
D5067_0018020  ppnP; pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
D5067_0005955  pgeF; polyphenol oxidase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D5067_0019050  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
D5067_0006385  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
D5067_0006315  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
D5067_0019700  yjjX; non-canonical purine NTP phosphatase [KO:K01529] [EC:3.6.1.73]
D5067_0003900  XTP/dITP diphosphatase [KO:K01519] [EC:3.6.1.66]
D5067_0018365  xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
D5067_0006390  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
D5067_0019170  GMP reductase [KO:K00364] [EC:1.7.1.7]
D5067_0014830  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
D5067_0000565  guanylate kinase [KO:K00942] [EC:2.7.4.8]
D5067_0005365  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
D5067_0007435  nrdA; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
D5067_0005360  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
D5067_0007430  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
D5067_0020585  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
D5067_0018860  dGTPase [KO:K01129] [EC:3.1.5.1]
D5067_0007260  5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
D5067_0005570  HD family hydrolase [KO:K06952] [EC:3.1.3.89]
D5067_0000555  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
D5067_0000780  gppA; guanosine-5'-triphosphate,3'-diphosphate diphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
D5067_0006435  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
D5067_0004775  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
D5067_0000895  cyaA; class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
D5067_0021000  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
D5067_0013035  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
D5067_0008615  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
D5067_0004710  LOG family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
D5067_0007895  adenine deaminase [KO:K01486] [EC:3.5.4.2]
D5067_0020780  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
D5067_0017540  adenylate kinase [KO:K00939] [EC:2.7.4.3]
D5067_0004780  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
D5067_0003455  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
D5067_0019435  apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [KO:K01525] [EC:3.6.1.41]
D5067_0004840  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
D5067_0004835  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
D5067_0004830  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
D5067_0014845  hpxO; FAD-dependent urate hydroxylase HpxO [KO:K16839] [EC:1.14.13.113]
D5067_0014835  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
D5067_0000420  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
D5067_0014840  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
D5067_0014815  hpxA; allantoin racemase [KO:K16841] [EC:5.1.99.3]
D5067_0014810  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
D5067_0014755  hpxK; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
D5067_0014760  alanine--glyoxylate aminotransferase family protein [KO:K00839] [EC:2.6.1.112]
D5067_0003315  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
D5067_0003320  urease subunit beta [KO:K01429] [EC:3.5.1.5]
D5067_0003325  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
D5067_0014800  AtzE family amidohydrolase [KO:K22601] [EC:2.1.3.5]
D5067_0014790  hpxW; oxamate amidohydrolase [KO:K22602] [EC:3.5.1.126]
D5067_0020485  carbamate kinase [KO:K00926] [EC:2.7.2.2]
D5067_0005445  carbamate kinase family protein [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ehu00030  Pentose phosphate pathway
ehu00220  Arginine biosynthesis
ehu00250  Alanine, aspartate and glutamate metabolism
ehu00260  Glycine, serine and threonine metabolism
ehu00340  Histidine metabolism
ehu00630  Glyoxylate and dicarboxylate metabolism
ehu00730  Thiamine metabolism
ehu00740  Riboflavin metabolism
ehu00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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